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In the war against diseases, nerve cells need their armor
In a new study, researchers at the Montreal Neurological Institute (MNI), McGill University, and the Université de Montréal have discovered an essential mechanism for the maintenance of the normal structure of myelin, the protective covering that insulates and supports nerve cells (neurons). view more (2008-11-13)
New Tools Developed for Studying Neurodegenerative Brain Disorders
Penn State researchers have created an elegantly simple model of an axon-the extension of a neuron that communicates with other neurons-and have used this model to reproduce a change in the axon's shape that is characteristic of neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. view more (2006-03-22)
Proteins anchor memories in our brain
A University of Utah study suggests that memories are held in our brains because certain proteins serve as anchors, holding other proteins in place to strengthen synapses, which are connections between nerve cells. view more (2006-11-22)
Lipids play important role in nervous system development
Blocking a signaling lipid can keep nerves from developing the arm-like extensions they need to wire the body and may even cause neurons to die, researchers have found. view more (2005-10-25)
Gradient guides nerve growth down spinal cord
The same family of chemical signals that attracts developing sensory nerves up the spinal cord toward the brain serves to repel motor nerves, sending them in the opposite direction, down the cord and away from the brain. view more (2005-08-15)
Nanomedicine opens the way for nerve cell regeneration
The ability to regenerate nerve cells in the body could reduce the effects of trauma and disease in a dramatic way. In two presentations at the NSTI Nanotech 2007 Conference, researchers describe the use of nanotechnology to enhance the regeneration of nerve cells. view more (2007-05-21)
Cancer-causing protein may heal damaged spinal cord and brain cells
Cancer researchers at Columbia University Medical Center have found that a protein known for driving the growth of cancer also plays a surprising role in restoring the ability of neurons to regenerate, making it an important target for addressing spinal cord damage or neurological diseases like Alzheimer's. view more (2006-06-29)
New roles for growth factors: Enticing nerve cells to muscles
During embryonic development, nerve cells hesitantly extend tentacle-like protrusions called axons that sniff their way through a labyrinth of attractive and repulsive chemical cues that guide them to their target. view more (2006-06-16)
USC researchers closer to cure for multiple sclerosis and other myelin-related diseases
A breakthrough finding on the mechanism of myelin formation by Jonah Chan, assistant professor of cell and neurobiology at the Keck School of Medicine of the University of Southern California, could have a major impact on the treatment of diseases such as multiple sclerosis and demyelination as a result of spinal cord injuries. view more (2006-11-03)
Neurons grown from embryonic stem cells restore function in paralyzed rats
For the first time, researchers have enticed transplants of embryonic stem cell-derived motor neurons in the spinal cord to connect with muscles and partially restore function in paralyzed animals. view more (2006-06-21)
Protein protects against nerve degeneration
A protein called NMNAT protects against nerve cell degeneration in fruit flies and mice, said Baylor College of Medicine researchers in a report in the Public Library of Science Biology that appears online today. view more (2006-12-01)
Major breakthrough in the mechanism of myelin formation
The group of Dr. Michel Cayouette, researcher at Institut de recherches cliniques de Montréal (IRCM), and Dr. Jonah Chan, collaborator at the University of Southern California, will publish in the next issue of the prestigious scientific journal Science, the results of their study that could have a major impact on the treatment of diseases... view more... (2006-11-03)
Cause of nerve fiber damage in multiple sclerosis identified
Researchers have identified how the body's own immune system contributes to the nerve fiber damage caused by multiple sclerosis, a finding that can potentially aid earlier diagnosis and improved treatment for this chronic disease. view more (2006-10-17)
COPAXONE® may repair nerve damage in Multiple Sclerosis patients
Clinical research data published in the December issue of Multiple Sclerosis provided evidence that COPAXONE® (glatiramer acetate injection) may offer protection from axonal injury and induced neuronal metabolic recovery in patients with relapsing remitting multiple sclerosis (RRMS). view more (2005-11-15)
Mechanism for neurodenegerative diseases linked to transport proteins
Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, ALS and Kennedy disease. Understanding how this cell transport is blocked in these diseases may offer targets for future therapy. view more (2006-06-09)
Schizophrenia and bipolar disorder could have similar genetic causes (pp 758, 798)
Issue 6 September 2003 Embargoed 0001 h (London time) 5 September 2003. Authors of a study in this week's issue of THE LANCET provide strong evidence that schizophrenia and bipolar disorder have a similar genetic cause arising from reduced expression of genes responsible for myelin development of the central nervous system. Schizophrenia and... view more... (2003-09-03)
Most important actors in the growth process of neurons identified
Defects in the growth process of our neurons often underlie brain or nerve diseases, such as Alzheimer's disease or multiple sclerosis. view more (2006-10-12)
Identification of a key gene required for brain neural circuit formation
An international team of scientists, lead by Dr. Frederic Charron at the IRCM, and Drs Ami Okada, Sue McConnell, and Marc Tessier-Lavigne in the USA, have made a discovery which could help treat spinal cord injuries and neurodegenerative diseases. view more (2006-11-02)
Protein key to neuro-regeneration
Researchers at the Peninsula Medical School in the South West of England, University College London, the San Raffaele Scientific Institute in Milan and Cancer Research UK, have for the first time identified a protein that is key to the regeneration of damage in the peripheral nervous system and which could with further research lead to... view more... (2008-05-21)
Growth factor stimulates rapid extension of key motor neurons in brain
A growth factor known to be important for the survival of many types of cells stimulates rapid extension of corticospinal motor neurons - critical brain cells that connect the cerebral cortex with the spinal cord and that die in motor neuron diseases like amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease). view more (2006-11-06)
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