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Cell wall of pneumonia bacteria can cause brain and heart damage
Investigators at St. Jude Children's Research Hospital have discovered in mouse models how cell walls from certain pneumonia-causing bacteria can cause fatal heart damage; researchers have also shown how antibiotic therapy can contribute to this damage by increasing the number of cell wall pieces shed by dying bacteria. The team also demonstrated... view more... (2006-10-25)
Rescuing injured hearts by enhancing regeneration
Using a two-drug approach, researchers at Children's Hospital Boston have demonstrated that it may be possible to rescue heart function after a heart attack and protect the heart from scarring. view more (2006-10-10)
Researchers safely regenerate failing mouse hearts with programmed embryonic stem cells
Mayo Clinic researchers have safely transplanted cardiac preprogrammed embryonic stem cells into diseased hearts of mice successfully regenerating infarcted heart muscle without precipitating the growth of a cancerous tumor — which, so far, has impeded successful translation into practice of embryonic stem cell research. view more (2007-02-28)
Using stem cells to help heart attack victims
New research at The University of Nottingham is paving the way for techniques that use stem cells to repair the damage caused by heart attacks. view more (2007-07-30)
Top 10 research advances include studies on genetics and stem cell research, stents
Several new studies on genetics and stem cell research, along with studies that continue to debate the use of stents to clear coronary artery blockages are among the top research advances in heart disease and stroke for 2007, said Daniel W. Jones, M.D., president of the American Heart Association. view more (2007-12-21)
UCLA stem cell researchers create heart and blood cells from reprogrammed skin cells
Stem cell researchers at UCLA were able to grow functioning cardiac cells using mouse skin cells that had been reprogrammed into cells with the same unlimited properties as embryonic stem cells. view more (2008-04-30)
Human derived stem cells can repair rat hearts damaged by heart attack
When human heart muscle cells derived from embryonic stem cells are implanted into a rat after a heart attack, they can help rebuild the animal's heart muscle and improve function of the organ, scientists report in the September issue of Nature Biotechnology. view more (2007-08-27)
Can heart tissue be regenerated?
When human hearts are injured, as during a heart attack, healthy tissue normally can't regrow. Researchers now demonstrate in rats that a sponge-like patch, soaked in a compound called periostin and placed over the injury, can not only get heart cells to begin dividing and making copies of themselves again, but also improves heart function. view more (2007-07-18)
System to analyze beating heart stem cells could lead to heart attack treatments
New research at the University of Nottingham, funded by the Biotechnology and Biological Sciences Research Council (BBSRC), is paving the way for techniques that use stem cells to repair the damage caused by heart attacks. view more (2007-07-30)
Aetiology of congenital heart disease explained
Researchers at Karolinska Institutet have identified the mechanisms behind the serious, congenital heart condition that can sometimes develop in children of women with a rheumatic disease. view more (2005-02-07)
Geron Demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction
Geron Corporation (Nasdaq: GERN) today reported its scientists and collaborators have demonstrated that human embryonic stem cell (hESC)-derived cardiomyocytes improve heart function when transplanted after myocardial infarction. view more (2007-08-27)
ESC Congress 2003: Human Embryonic Stem Cell Derived Cardiomyocytes: A Novel Source for Cell Therapy
IMPORTANT: This press release accompanies both a presentation and an ESC press conference given at the ESC Congress 2003. Written by the investigator himself/herself, this press release does not necessarily reflect the opinion of the European Society of Cardiology Adult heart cells have limited regenerative capacity and therefore any significant... view more... (2003-09-01)
Genes identified that protect against heart damage from chemotherapy
A series of genes that protect cells from the powerful, common chemotherapeutic agent doxorubicin has been identified by researchers working to understand how the drug also can destroy the heart. view more (2007-12-04)
Stem-cell transfer could improve cardiac functioning after heart attack (pp 121, 141)
Results of a randomised trial in this week's issue of THE LANCET suggest that the transfer of adult stem cells derived from bone marrow could improve cardiac functioning after heart attack. Evidence is emerging that adult stem cells from bone marrow have therapeutic potential for restoring cardiac cells among people who have had heart attack.... view more... (2004-07-07)
Stem cells not the only way to fix a broken heart
Researchers appear to have a new way to fix a broken heart. They have devised a method to coax heart muscle cells into reentering the cell cycle, allowing the differentiated adult cells to divide and regenerate healthy heart tissue after a heart attack. view more (2009-07-24)
Skeletal Muscle Repairs the Heart; Gray Wolves Maintain the Food Chain in Winter: Press Release from PLoS Biology
Heart Repair Gets New Muscle Some organs in the human body deal with injury better than others. A flesh wound or muscle tear might hurt, but, assuming you are otherwise healthy, both will heal. The prognosis for a heart attack, on the other hand, is not so clear-cut. view more (2005-03-08)
New source of heart stem cells discovered
Researchers at Children's Hospital Boston are continuing to document the heart's earliest origins. Now, they have pinpointed a new, previously unrecognized group of stem cells that give rise to cardiomyocytes, or heart muscle cells. view more (2008-06-23)
Injection reverses heart-attack damage
Injured heart tissue normally can't regrow, but researchers at Children's Hospital Boston have now laid the groundwork for regenerating heart tissue after a heart attack, in patients with heart failure, or in children with congenital heart defects. view more (2009-07-24)
Cardiac cell transplant studies show promise in cardiac tissue repair
Two studies published in the current issue of CELL TRANSPLANTATION (17:6) examine the efficacy of transplanting bone marrow cells (BMCs) for the repair of heart tissue. view more (2008-09-04)
Researchers at UH Explore use of Fat Cells as Heart Attack Therapy
For those of us trained to read nutrition labels, conventional wisdom tells us that fat isn't good for the heart. But a team of University of Houston researchers has set out to use fat cells to beef up heart muscles damaged by heart attack - and they're using an out-of-this-world device to do it. view more (2008-10-28)
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