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Progress in understanding the malarial parasite
About 2 million people die of malaria every year, of which more than a million are children in sub-Saharan Africa. Malaria is caused by a protozoan parasite belonging to the genus Plasmodium, and Plasmodium falciparum is responsible for the most severe form of malaria. view more (2007-09-14)
Finding a cure for cancer: the holy grail of science
To find a cure for cancer, the modern-day plague of our society - is synonymous to finding the holy grail of science. view more (2006-11-22)
Novel molecular 'signature' marks DNA of embryonic stem cells
A team of scientists announced today a critical step on the path of realizing the promise of embryonic stem (ES) cells for medicine. view more (2006-04-21)
EU research suggests that PCBs damage sperm - but finds no dramatic effect on male fertility
Research by an EU-supported international team of scientists has shown that polychlorinated biphenyls (PCBs)[1]-synthetic organic chemicals found widely in the environment and absorbed in the diet - may damage sperm. view more (2005-10-13)
Promising cell protein may play role in infection and dry eye
Plasminogen Activator Inhibitor Type 2 (PAI-2), a protein found in various cell types including the skin, has been discovered in the tissue covering the eye and may have future clinical implications in various pathologies of the ocular surface such as eye infection or dry eye. view more (2006-05-17)
UT Southwestern researchers find alterations in brain's circuitry caused by cocaine
Cocaine causes specific alterations in the brain's circuitry at a genetic level, including short-term changes that result in a high from the cocaine, as well as long-term changes seen in addiction. view more (2005-10-24)
How embryonic stem cells maintain their identity
Two studies in the April 21, 2006 Cell report new details of the "genetic program" that affords embryonic stem cells the flexibility to give rise to any cell type in the body. view more (2006-04-21)
Molecular partners required for appropriate neuronal gene repression
In their efforts to understand the complex biology of life, scientists often seek to isolate individual elements of the puzzle for study, to break the problem down to a more manageable size. Single genes and molecules are closely analyzed to better understand their specific interactions with other single entities within larger systems. view more (2005-08-04)
Researchers uncover new mechanism of tumor suppressor
Researchers from the University of Colorado-Denver and Health Sciences Center and Stanford University have discovered a molecular mechanism that explains how cells respond to DNA damage and other acute stresses, and if disrupted can cause cancer. view more (2006-05-22)
Targeting the dosage compensation complex
Three independent research papers in the April 1 issue of G&D detail the chromosome-wide binding of the Drosophila dosage compensation complex (DCC) to the single male X chromosome, shedding new light on the mechanism of DCC targeting. view more (2006-03-17)
Delving deeper into the machinery of cocaine addiction
Researchers are now understanding in greater detail the molecular machinery underlying the short-term brain changes that produce the high of cocaine, as well as the longer-term changes behind addiction. Their findings offer hope for targeted drugs that can short-circuit that addiction machinery. view more (2005-10-20)
Gene-regulating enzyme is also a target for anti-depressive drugs
In 2005, professor Ramin Shiekhattar, Ph.D., at The Wistar Institute and his colleagues reported details about an enzyme involved in appropriately repressing sets of neuronal genes in non-neuronal cells. view more (2006-06-26)
Mapping dynamic Polycomb group proteins during Drosophila development
The developmental passage from a ball of cells to a fruit-fly is a very complicated process involving both temporal and spatial regulation of genes and pathways. view more (2006-04-20)
Rong Li Lab demonstrates the process of mammalian egg maturation
he Rong Li lab team has answered an important question about how mammalian eggs undergo maturation through an intricate process of asymmetric cell division. The team discovered a novel pathway by which chromatin exerts command on the cell membrane to produce a specialized machinery used for cell division. view more (2007-02-06)
Regulating the Nuclear Architecture of the Cell
An organelle called the nucleolus resides deep within the cell nucleus and performs one of the cell's most critical functions: it manufactures ribosomes, the molecular machines that convert the genetic information carried by messenger RNA into proteins that do the work of life. view more (2006-12-11)
Cancer is a stem cell issue
There is an urgent reason to study stem cells: stem cells are at the heart of some, if not all, cancers. view more (2007-02-20)
How body size is regulated: International study discovers ten new genes related to human growth
Scientists are beginning to unravel the question why people distinctly vary in size. view more (2008-05-12)
The meiotic histone code
Dr. Terry Orr-Weaver and colleagues (MIT & Nagasaki University School of Medicine) present the first genetic analysis of the recently identified nucleosomal histone kinase, NHK-1. view more (2005-10-17)
Single molecular 'mark' seen as pivotal for genome compaction in spores and sperm
In higher order animals, genetic information is passed from parents to offspring via sperm or eggs, also known as gametes. In some single-celled organisms, such as yeast, the genes can be passed to the next generation in spores. view more (2006-09-18)
Study shows that genetic quality of sperm deteriorates as men age
New research indicates that the genetic quality of sperm worsens as men get older, increasing a man's risk of being infertile, fathering unsuccessful pregnancies and passing along dwarfism and possibly other genetic diseases to his children. view more (2006-06-06)
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