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Beyond genes: Lipid helps cell wall protein fold into proper shape
A protein that provides a vital passage through a bacterium's outer cell wall will misfold and malfunction if that wall is built of the 'wrong' material, scientists at The University of Texas Medical School at Houston report in a finding that has long-term implications for understanding diseases caused by misfolded proteins such as cystic... view more... (2005-07-18)

Researchers find effective, cheap treatment for cystic fibrosis lung disease
Working half a world away from each other, two teams of medical scientists have identified what they believe is a simple, effective and inexpensive treatment to reduce lung problems associated with cystic fibrosis, the leading fatal genetic illness among whites.   view more (2006-01-19)

Scientists determine structure of enzyme that disrupts bacterial virulence
A team of biomedical researchers from Brandeis University and the University of Texas at Austin has determined the first 3-dimensional structure of an enzyme that may be pivotal in preventing certain bacterial infections in plants, animals and humans.   view more (2005-08-31)

Gene therapy accelerates healing of damaged skeletal muscle
University of Pittsburgh School of Medicine researchers have successfully used gene therapy to accelerate muscle regeneration in experimental animals with muscle damage, suggesting this technique may be a novel and effective approach for improving skeletal muscle healing, particularly for serious sports-related injuries.   view more (2006-06-05)

Bone marrow cells can become functional gut lining cells
Researchers report the discovery that cells used in bone marrow transplantation can develop into new cells lining the gut, according to a study by Yale School of Medicine in the Proceedings of the National Academy of Sciences.   view more (2006-03-03)

IL-21 receptor plays an essential role in the Th2 immune response
During the immune response cells known as Th2 cells express a variety of cytokines (e.g. interleukin-4, -5, and -13), many of which stimulate B cells to proliferate and produce antibodies.   view more (2006-06-16)

Rice breakthrough could prevent multiple fibrotic diseases
A scientific breakthrough at Rice University could lead to the first treatment that prevents the build-up of deadly scar tissue in a broad class of diseases that account for an estimated 45 percent of U.S. deaths each year.   view more (2007-01-19)

Special issue on cystic fibrosis in The Journal of Pediatrics
Cystic fibrosis is a common, fatal genetic disease in which a gene causes the body to produce abnormally thick, sticky mucus.   view more (2005-10-04)

Breath test offers hope for early detection of lung-bacteria growth in cystic fibrosis
Breath-analysis testing may prove to be an effective, non-invasive method for detecting the damaging lung-bacteria growth seen in cystic fibrosis, which would allow for early stage treatments that can extend the health of people with this disease.   view more (2005-10-18)

Study proves genetic variations influence cystic fibrosis' severity
Subtle differences in other genes - besides the defective gene known to cause the illness cystic fibrosis - can significantly modify the inherited disease's severity, a large new multi-center national study has concluded.   view more (2005-10-06)

Advanced genomics and proteomics improve the diagnosis and treatment of a deadly lung disease
In an article in the Jan. 15 issue of the American Journal of Respiratory Critical Care Medicine, University of Pittsburgh researchers report that a serious, life-threatening form of pulmonary fibrosis, called idiopathic pulmonary fibrosis, lacks all the hallmarks of inflammation and is probably unnecessarily treated with anti-inflammatory drugs.   view more (2006-01-12)

A candidate gene for familial idiopathic pulmonary fibrosis identified
ELMOD2-gene is a prime candidate gene for familial idiopathic pulmonary fibrosis, suggests the recent study published by the researchers at the University and University Hospital of Helsinki, Finland.   view more (2006-06-29)

Mayo Clinic Cancer Center finds possible genetic link to pancreatic cancer
Mayo Clinic researchers have found the risk of developing pancreatic cancer at a young age (under 60) to be twice as high for people who carry a mutation of the gene that causes cystic fibrosis, compared to noncarriers.   view more (2005-10-21)

Test predicts risk of liver scarring after transplant, study shows
An estimated 20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis, scarring of the new organ severe enough to impair its ability to function normally within five years of transplantation.   view more (2005-10-06)

Cystic fibrosis patients may breathe easier, thanks to bioengineered antimicrobials
By better understanding how antimicrobials bind and thereby get inactivated in the mucus of air passages, researchers at the University of Illinois may have found a way to help cystic fibrosis patients fight off deadly infections.   view more (2007-09-25)

Key Found to Kill Cystic Fibrosis Superbug
Researchers from the Schulich School of Medicine & Dentistry at The University of Western Ontario , working with a group from Edinburgh, have discovered a way to kill the cystic fibrosis superbug, Burkholderia cenocepacia.   view more (2007-04-25)

MRI contrast agent linked to rare disease
New research has shown a possible association between a popular magnetic resonance imaging (MRI) contrast agent and the incidence of a rare disease called nephrogenic systemic fibrosis (NSF) in patients with kidney disease.   view more (2007-01-29)

Scientists use PET scans to monitor lung inflammation noninvasively
A noninvasive approach for assessing lung inflammation should accelerate efforts to develop drugs for inflammatory lung conditions like cystic fibrosis and pneumonia, scientists at Washington University School of Medicine in St. Louis report.   view more (2006-03-09)

Making headway against hepatitis C: SLU study shows new drug combo effective in non-responders
Saint Louis University Liver Center scientists are presenting research today on a more effective way to treat hepatitis C patients who have been unresponsive to current drug therapies.   view more (2006-10-30)

NHLBI media availability: Treatment shows long-term benefits for cystic fibrosis patients
New research suggests that inhaling hypertonic saline, a water-based concentrated salt solution, could provide long-term benefits for lung health in patients with cystic fibrosis (CF).   view more (2006-01-19)
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