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Penn researchers discover key to how SARS virus infects cells
Researchers from the University of Pennsylvania School of Medicine have found that inhibitors of an enzyme called cathepsin L prevent the SARS (severe acute respiratory syndrome) virus from entering target cells. SARS is caused by an emergent coronavirus. view more (2005-08-02)
New Study Shows SARS Can Infect Brain Tissue
Severe acute respiratory syndrome (SARS), by its very name, indicates a disease of the respiratory tract. view more (2005-09-15)
Researchers find 'secret weapon' used by SARS virus
In 2003, the highly contagious and often-deadly mystery disease now called SARS emerged explosively out of Southern China. It eventually killed an estimated 916 people in Asia, Europe, and North and South America-nearly one in ten of those it infected. view more (2006-08-08)
Casting a wide net to fight coronaviruses
Coronaviruses-the family of viruses that causes the common cold-gained widespread recognition when the deadly severe acute respiratory syndrome, familiarly known as SARS, killed at least 800 people in 2003. view more (2005-09-06)
Emerging Infectious Diseases Of Wildlife - Microbiology Today: November 2003 issue
Wildlife is an important source of diseases that are a risk to the health of man and his domesticated stock. This was very clearly demonstrated earlier this year when the masked palm civet was implicated as a possible wild animal source for the SARS (Severe Acute Respiratory Syndrome) coronavirus. In the November 2003 issue of Microbiology Today... view more... (2003-10-28)
Enzyme inhibitors block replication Of SARS virus
Researchers have known since 2003 that a site on the virus is responsible for mediating proteases that allow the virus to replicate. Since then researchers have been testing protease inhibitors to lock up this site, known as SARS 3CLpro, and effectively stop the virus from infecting additional cells in the body. view more (2006-03-28)
New study finds no link between Kawasaki disease and newly discovered coronavirus
A newly described virus is not a cause of Kawasaki disease, according to an article by a group of researchers in Denver, Colorado. view more (2006-11-21)
In-shell vaccine for chick disease
Infectious bronchitis virus (IBV) causes losses of £23.6M a year to the UK poultry industry but scientists are now developing a new way to vaccinate chicks against the disease - one that can be delivered while they are still in their egg. view more (2007-01-05)
Researchers probe enzyme that may lead to new SARS drugs
Researchers at the University of Illinois at Chicago and two other institutions have unraveled the structure of an important new drug target from the virus that causes SARS, severe acute respiratory syndrome. view more (2006-04-05)
SARS - the first comprehensive description of the damage caused by the virus
Research News in the Journal of Pathology Doctors working near to the first outbreak of severe acute respiratory syndrome (SARS) Guangdong, China, have just published the first histopathological description of the effects of this viral infection in the Journal of Pathology. Basing their findings on autopsies of three people who died of SARS, Dr... view more... (2003-06-30)
Discovery may help defang viruses
Researchers may be able to tinker with a single amino acid of an enzyme that helps viruses multiply to render them harmless, according to molecular biologists who say the discovery could pave the way for a fast and cheap method of making vaccines. view more (2007-08-29)
New Clorox disinfectant is EPA registered to kill both known types of MRSA
While MRSA has been an issue in healthcare settings for years, CA-MRSA outbreaks in the community have been on the rise, with the greatest risk in community settings such as fitness clubs, in sports teams, at schools and daycare centers. view more (2008-05-06)
Details of the life cycle of SARS coronavirus
A team of scientists studying Severe Acute Respiratory Syndrome (SARS) has, for the first time, described how the SARS virus manufactures several of the materials required for making copies of itself. "It is essential, when you are looking for ways to stop a disease, that you know exactly how viruses make copies of themselves and... view more... (2003-07-08)
Study Implicates Human Coronavirus As Main Cause Of SARS
Early online publication: Tuesday 8 April 2003 FOR IMMEDIATE RELEASE Research from Hong Kong fast-tracked for publication on THE LANCET's website--www.thelancet.com--provides evidence that a new virus belonging to the family Coronaviridae is likely to be the main cause of Severe Acute Respiratory Syndrome (SARS). Malik Peiris from the University... view more... (2003-04-08)
SARS without pneumonia could be common in outbreak areas (p 841)
Results of research from Hong Kong in this week's issue of THE LANCET suggests that severe acute respiratory syndrome (SARS) without pneumonia could be common among populations affected by SARS outbreaks. SARS has now affected 30 countries in five continents, with more than 8400 cases and more than 910 deaths. A novel virus, the... view more... (2004-03-10)
Animal studies show promise for development of human SARS immunisation (pp 2102, 2122, 2139)
An article and research letter in this week's issue of THE LANCET provide evidence for the effectiveness of experimental SARS immunisation in animal studies. Although further research is required, these preliminary results show the potential for the development of human SARS immunisation. Alexander Bukreyev from the US National Institutes of... view more... (2004-06-23)
SARS antiviral drug discovered: traditional antimalarial drug works against SARS coronavirus infection
Virologists from the Katholieke Universiteit Leuven (K.U.Leuven) in Belgium report that chloroquine, a widely used antimalarial drug, exhibits antiviral activity against the SARS coronavirus. Chloroquine is an inexpensive and safe drug available worldwide. SARS (Severe Acute Respiratory Syndrome) is a respiratory illness which was first... view more... (2004-09-03)
A Different Antiviral For Treating SARS (p 2045)
A preliminary study published as a fast-track research letter in this week's issue of THE LANCET suggests that the antiviral agent glycyrrhizin could be more effective than other antivirals in the treatment of severe acute respiratory syndrome (SARS). Ribavirin is the most commonly used antiviral for treating SARS infection, used in combination... view more... (2003-06-11)
Animal model shows early promise for SARS vaccine (p 1895)
Embargoed 0001 h (London time) 5 December 2003. US authors of a research letter in this week's issue of THE LANCET highlight preliminary findings which could mark an important step in the development of a human vaccine for severe acute respiratory syndrome (SARS). A genetically engineered vaccine was found to be effective in triggering an immune... view more... (2003-12-03)
Novel Coronavirus Confirmed As Causative Agent Of SARS
Leading scientists worldwide investigating the cause of Severe Acute Respiratory Syndrome (SARS) confirm that a novel coronavirus is the primary cause of the disease. The study is published on THE LANCET's website (www.thelancet.com) at 0001 H Tuesday 22 July UK time. SARS was first reported in China in November 2002, with over 8300 cases and 812... view more... (2003-07-18)
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