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10 Million Euro Technology Project Makes Europe a leader in Biocrystallography
A project to create a common platform throughout Europe for researchers working in the field of 'biological crystallography' is underway thanks to a grant of 10 million euros from the EU's 6th Framework Programme (FP6). view more (2005-02-08)
BBSRC welcome first female head of biotechnology research council
BBSRC welcome today's announcement from Lord Sainsbury that Professor Julia Goodfellow from Birkbeck College, University of London, will become one of the first women to head one of the government's seven scientific Research Councils. As Chief Executive of the Biotechnology and Biological Sciences Research Council, Professor Goodfellow will take... view more... (2001-08-15)
A clearer view of crystal growing
As technology progresses toward ever finer microelectronic structures, the wavelength of the ultraviolet radiation used to depict them has to be shortened. The emerging generation of photolithographic processes works at 157 nanometers - a wavelength at which glass and even quartz glass are not transparent enough. The preferred material here is... view more... (2002-09-20)
Mammoth project reveals frozen secrets
Which way does a mammoth skeleton point in Siberia? No, it’s not a Christmas cracker joke. To find the answer you have to look in a rather surprising place – the Institute of Physics’ new online archive. In an article published in the first edition of Proceedings of the Physical Society in 1874, John Rae writes about the... view more... (2003-01-08)
Improved technique determines structure in membrane proteins
Understanding the form and function of certain proteins in the human body is becoming faster and easier, thanks to the work of researchers at the University of Illinois. view more (2008-08-18)
Researchers solve first structure of a key to intact DNA inheritance
Researchers have solved the structure of a DNA-protein complex that is crucial in the spread of antibiotic resistance among bacteria. Knowing this structure also provides fundamental insight into how cells successfully divide into two new cells with intact DNA. view more (2007-12-21)
Double binding sites on tumor target may provide future combination therapy
Researchers from the University of Pennsylvania School of Medicine and colleagues at Merck Serono Research in Germany have found that two drugs bind to receptor sites on some tumors in different places at the same time, suggesting the possibility of a new combination therapy for certain types of cancer. view more (2008-04-09)
CCLRC to play pivotal role in e-science
CCLRC (Council for the Central Laboratory of the Research Councils) welcomes the government's announcement today that offers extra funding for e-science. The extra £5 million over three years awarded to CCLRC will enable it to drive the development of e-science as a key technology for the next generation of major scientific facilities at the... view more... (2000-11-22)
Findings reveal how dengue virus matures, becomes infectious
Biologists at Purdue University have determined why dengue virus particles undergo structural changes as they mature in host cells and how the changes are critical for enabling the virus to infect new host cells. view more (2008-03-28)
Scientists learn structure of enzyme in unusual virus
Biologists have determined the three-dimensional structure of an unusual viral enzyme that is required in the assembly of new viruses. view more (2007-09-18)
Media Invitation: 20 years of excellence - Catch-up on the latest news from ISIS and tour the facility
ISIS celebrates 20 years of excellence view more (2004-12-06)
Structure of enzyme against chemical warfare agents determined
The enzyme DFPase from the squid Loligo vulgaris, is able to rapidly and efficiently detoxify chemical warfare agents such as Sarin, which was used in the Tokyo subway attacks in 1995. view more (2009-01-29)
Dartmouth researchers find new protein function
A group of Dartmouth researchers has found a new function for one of the proteins involved with chromosome segregation during cell division. view more (2009-01-09)
Properties of Unusual Virus Revealed in Researchers
A team of researchers from Penn State University and the University of Chicago has uncovered clues that may explain how and why a particular virus, called N4, injects an unusual substance -- an RNA polymerase protein -- into an E. coli bacterial cell. The results, which are published in the current issue of the journal Molecular Cell, contribute... view more... (2008-12-09)
Iowa State University researchers discover structure of key Ebola protein
Research led by Iowa State University scientists has them a step closer to finding a way to counter the Ebola virus. view more (2009-01-13)
Groundbreaking study on complex movements of enzymes
A groundbreaking study has revealed in great detail how enzymes in the cell cooperate to make fat. These enzymes are integrated into a single molecular complex known as fatty acid synthase. This complex is regarded as a potential target for developing new anti-obesity and anti-cancer drugs. view more (2009-02-12)
Antibody key to treating variant CJD, scientists find
Scientists at the University of Liverpool have determined the atomic structure of the 'binding' between a brain protein and an antibody that could be key to treating patients with diseases such as variant CJD. view more (2009-03-04)
UCLA researchers clarify function of glucose transport molecule
Researchers at the David Geffen School of Medicine at UCLA have solved the structure of a class of proteins known as sodium glucose co-transporters (SGLTs), which pump glucose into cells. view more (2008-07-07)
Structural polymorphism of 441-residue Tau at single residue resolution
Worldwide almost 30 million suffer from Alzheimer's disease, an irreversible, neurodegenerative condition that is eventually fatal. view more (2009-02-17)
Scripps scientists find structure of a protein that makes cancer cells resistant to chemotherapy
A research team at the Scripps Research Institute has obtained the first glimpse of a protein that keeps certain substances, including many drugs, out of cells. The protein, called P-glycoprotein or P-gp for short, is one of the main reasons cancer cells are resistant to chemotherapy drugs. Understanding its structure may help scientists design... view more... (2009-03-27)
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