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New malaria enzyme laid bare with help of computer calculations
Using only computers, a research team at Uppsala University in Sweden has managed to reveal both the structure and the function of a newly discovered enzyme from the most dangerous malaria parasite, Plasmodium falciparum. All that was needed was the amino acid sequence of the enzyme. The findings... view more (2004-12-07)

Progress in understanding the malarial parasite
About 2 million people die of malaria every year, of which more than a million are children in sub-Saharan Africa. Malaria is caused by a protozoan parasite belonging to the genus Plasmodium, and Plasmodium falciparum is responsible for the most severe form of malaria.   view more (2007-09-14)

Certain combination therapy found more effective for treating malaria in African children
Ugandan children who received the combination therapy of artemether-lumefantrine experienced a lower rate of treatment failure compared to other combination therapies, according to a study in the May 23/30 issue of JAMA, a theme issue on malaria.   view more (2007-05-23)

Penicillin, amoxicillin: Step aside for strep throat treatment
Doctors today presented more evidence that it's time for long-time antibiotic stalwarts like penicillin and amoxicillin to step aside when it comes to the treatment of strep throat.   view more (2005-12-19)

New cancer drug hope
Scientists helping to develop the next generation of cancer-beating drugs say they have had a major breakthrough with their latest results.   view more (2006-10-27)

Bigger is better when it comes to the G spot
DRUGS such as Viagra should work for some women- especially if they have a big G spot. This spot, famed for producing spectacular orgasms, turns out to be awash with the enzymes that these drugs act on. The term G spot, coined by Ernest Grafenberg in 1950, refers to an area a few centimetres up... view more (2002-07-03)

Research links 'ecstasy' to survival of key movement-related cells in brain
New research from the University of Cincinnati (UC) suggests that the widely abused club drug "ecstasy," or MDMA, can increase the survival of dopamine cells in the brain during fetal development.   view more (2006-10-19)

Research offers new approach to developing treatments for cocaine and amphetamine addiction
The study shows that highly addictive drugs, like cocaine and amphetamine, require a neurotransmitter called CART (Cocaine- and Amphetamine-Regulated Transcript) peptides to produce their maximal effects.   view more (2005-09-29)

AIDS Drug from Sunflowers
Sunflowers can produce a substance which prevents the AIDS pathogen HIV from reproducing, at least in cell cultures.   view more (2006-01-09)

SLU Researchers Uncover Direct Evidence on How HIV Invades Healthy Cells
Using sophisticated detection methods, researchers at the Saint Louis University Institute for Molecular Virology (IMV) have demonstrated the molecular mechanism by which the HIV virus infects, or integrates, healthy cells. The discovery could lead to new drug treatments for HIV.   view more (2005-12-22)

Drug resistance may travel same path as quorum sensing
The cellular "pumps" associated with multi-drug resistance in bacteria may also be involved in exporting signals responsible for cell-cell communication, a process known as quorum sensing.   view more (2006-02-07)

Morphine Makes Lasting - and Surprising - Change in the Brain
Morphine, as little as a single dose, blocks the brain's ability to strengthen connections at inhibitory synapses, according to new Brown University research published in Nature.   view more (2007-04-26)

New discovery may help doctors treat infertility
New research suggests that medications commonly referred to as fertility drugs may be ineffective for women who lack a gene called the estrogen receptor beta.   view more (2005-07-21)

Slipping past the blood brain barrier: Research shows potential treatment for brain cancer
A compound that kills cancer can sneak past the blood brain barrier, which protects the brain from foreign substances, to do its work in fighting a particularly invasive brain cancer.   view more (2005-08-23)

Chemotherapy after surgery extends survival for patients with advanced endometrial cancer
A new study has shown for the first time that giving two chemotherapy drugs to women with advanced endometrial cancer after surgery reduced the risk of recurrence by 29% and extended survival by 32% compared with women who received whole abdominal irradiation.   view more (2005-12-06)

Chemotherapy can be more toxic to brain cells than to cancer cells and may cause brain damage
Drugs used to treat cancer may damage normal, healthy brain cells more than the cancer cells they are meant to target.   view more (2006-11-30)

New study finds anabolic steroids may be addictive
A new study designed to test whether androgenic-anabolic steroids may be addictive found that hamsters exposed to the compounds demonstrated addictive behavior over time.   view more (2005-12-14)

Cholesterol treatment, including statins, may slow Alzheimer's disease progression
Cholesterol lowering drugs, including statins, may slow the progression of Alzheimer's disease, concludes a study in the Journal of Neurology Neurosurgery and Psychiatry.   view more (2005-11-17)

Antidepressants linked to lower child suicide rates
esearchers report an inverse relationship between antidepressant prescriptions and the rates of suicide in children and adolescents - a finding that contradicts the Food and Drug Administration's "black box" warning for selective serotonin reuptake inhibitor medications, also known as... view more (2006-11-02)

Columbia University researchers discover on-off switch for chronic pain
Chronic pain affects approximately 48 million people in the U.S. and current medications are either largely ineffective or have serious side effects.   view more (2006-07-20)

New study supports major change in diet treatment for diabetes
A low-fat vegan diet treats type 2 diabetes more effectively than a standard diabetes diet and may be more effective than single-agent therapy with oral diabetes drugs.   view more (2006-08-08)

Revolution in the fight against cancer & viruses
A recent scientific discovery could herald the introduction of fast, effective treatments for cancer and viruses.   view more (2006-05-26)

Insects and mammals share common fat-building pathway, study suggests
When it comes to gaining fat, insects and mammals may have something in common, researchers report in the Jan. 11, 2006, Cell Metabolism.   view more (2006-01-11)

Scientists pool information to boost understanding of drug action
As a result of the Human Genome Project, scientists now know the human DNA codes for about 20,000-25,000 genes, each of which could be a target for the development of new medicines. However, most scientists believe that only about 10% of these genes are likely targets for the drugs of the future.   view more (2005-12-01)

Harmless virus may hold key to more effective HIV drug discovery
A simple, harmless virus might hold the key to the more effective and efficient development of HIV and anti-viral drugs, UCI chemical biologists have found.   view more (2005-08-29)
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