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New malaria enzyme laid bare with help of computer calculations
Using only computers, a research team at Uppsala University in Sweden has managed to reveal both the structure and the function of a newly discovered enzyme from the most dangerous malaria parasite, Plasmodium falciparum. All that was needed was the amino acid sequence of the enzyme. The findings may represent a breakthrough for future... view more... (2004-12-07)

Scientists demonstrate feasibility of preventing malaria parasite from becoming sexually mature
Researchers have demonstrated the possibility of preventing the human malaria parasite, Plasmodium falciparum, which is responsible for more than a million malaria deaths a year, from becoming sexually mature.   view more (2008-06-03)

New hope for advances in treating malaria
Researchers at the University of Leeds have developed chemicals which kill the most deadly malaria-causing parasite, Plasmodium falciparum -- including those resistant to existing drugs.    view more (2009-04-22)

New cancer drug hope
Scientists helping to develop the next generation of cancer-beating drugs say they have had a major breakthrough with their latest results.   view more (2006-10-27)

Flesh-eating bacteria escape body's safety net
Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that so-called flesh-eating "Strep" bacteria use a specific enzyme to break free of the body's immune system, a finding which could potentially lead to new treatments for serious infections in human patients.   view more (2006-02-21)

Enzyme action creates protein linked to Alzheimer's disease
Researchers at UT Southwestern Medical Center have defined a key step in the production of beta-amyloid, a short protein that is thought to be responsible for the development of Alzheimer's disease.   view more (2005-08-15)

Measuring certain enzyme activity in urine shows promise for detection of bladder cancer
Measurement of an enzyme level (telomerase activity) in urine appears useful for detection of bladder cancer in men.   view more (2005-10-26)

Cell wall of pneumonia bacteria can cause brain and heart damage
Investigators at St. Jude Children's Research Hospital have discovered in mouse models how cell walls from certain pneumonia-causing bacteria can cause fatal heart damage; researchers have also shown how antibiotic therapy can contribute to this damage by increasing the number of cell wall pieces shed by dying bacteria. The team also demonstrated... view more... (2006-10-25)

Low-dose chemotherapy plus antiangiogenesis drug has activity in advanced breast cancer
Chemotherapy given in low, frequent doses - a novel strategy called "metronomic" delivery - achieved partial shrinkage of disease in some advanced breast cancer patients when given concurrently with an angiogenesis inhibitor.   view more (2005-12-09)

AIDS Drug from Sunflowers
Sunflowers can produce a substance which prevents the AIDS pathogen HIV from reproducing, at least in cell cultures.   view more (2006-01-09)

K-State professors discover enzyme responsible for creation of a beetle's hard shell
Kansas State University researchers think their discovery of the enzyme involved in the hardening of a beetle's exoskeleton or cuticle could lead not only to better pest control, but also help create similar strong, lightweight materials for use in aircraft and armor.   view more (2005-08-03)

When it comes to gene transcription, random pauses aren't quite so random, study finds
Of the thousands of proteins produced in our cells, few are as important as the enzyme RNA polymerase (RNAP), which has the unique ability to faithfully copy genetic information from DNA.   view more (2006-06-16)

Tumor cells that border normal tissue are told to leave
The thin, single-cell boundary where a tumor meets normal tissue is the most dangerous part of a cancer according to a new study by scientists at Washington University School of Medicine in St. Louis.   view more (2006-01-11)

Accelerated evolution converts RNA enzyme to DNA enzyme in vitro
This 'evolutionary conversion' provides a modern-day snapshot of how life as we understand it may have first evolved out of the earliest primordial mix of RNA-like molecules-sometimes referred to as the "pre-RNA world"-into a more complex form of RNA-based life (or the "RNA world") and eventually to cellular life based on DNA... view more... (2006-03-28)

Scientists determine structure of enzyme that disrupts bacterial virulence
A team of biomedical researchers from Brandeis University and the University of Texas at Austin has determined the first 3-dimensional structure of an enzyme that may be pivotal in preventing certain bacterial infections in plants, animals and humans.   view more (2005-08-31)

Omega-6 fats cause prostate tumors to grow twice as fast
Omega-6 fatty acids-such as those found in corn oil-caused human prostate tumors in cell culture to grow twice as quickly as tumors to which omega-6 fats had not been added, according to a study conducted at the San Francisco VA Medical Center.   view more (2006-02-01)

Common Enzyme is a Key Player in DNA Repair
A quarter century after they discovered it, researchers have identified the job of one of the most common DNA-damage response proteins.   view more (2006-01-12)

DNA size a crucial factor in genetic mutations, study finds
Researchers at Stanford University have created a larger-than-normal DNA molecule that is copied almost as efficiently as natural DNA.   view more (2005-10-27)

Coffee consumption linked to increased risk of heart attack for persons with certain gene variation
Individuals who have a genetic variation associated with slower caffeine metabolism appear to have an increased risk of non-fatal heart attack associated with higher amounts of coffee intake, according to a study in the March 8 issue of JAMA.   view more (2006-03-08)

Enzyme discovery sheds light on vitamin D
Surprising findings by Queen's researchers have shed new light on how the "sunshine vitamin" D - increasingly used to treat and prevent cancer and other diseases - is broken down by our bodies.   view more (2007-07-25)
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