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Identified mechanism in the malaria parasite to help it adapt to infected individuals
Plasmodium falciparum is responsible for the most severe forms of human malaria. Invasion of host red blood cells is an essential step of the complex life cycle of this parasite. view more (2007-08-03)
Genes involved in cell growth and cell division identified
A recent study shows that hundreds of genes contribute to cell growth and cell division. For the first time these genes, many of which are potential contributors to cancer, have been mapped in a single systematic study. view more (2006-02-23)
Food additive inhibits longevity enzyme in yeast, increases cell toxicity, new study finds
A common additive found in food and cosmetics has been found to inhibit the activity of sirtuins, enzymes associated with lifespan control in yeast and other organisms, according to a new study led by researchers at the University of California, Berkeley. view more (2005-12-16)
Gene therapy 'turns off' mutation linked to Parkinson's disease
A group of Northwestern University researchers is developing a novel gene therapy aimed at selectively turning off one of the genes involved in the development of Parkinson's disease. view more (2006-01-19)
Mice cloned from skin cells
Healthy and viable mice that survive until adulthood have, for the first time, been cloned from adult stem cells. Scientists from Rockefeller University, including Howard Hughes Medical Institute investigator Elaine Fuchs, used cells called keratinocyte stem cells, which represent a new model system for cloning. view more (2007-02-13)
New gene silencing therapy for cervical cancer
Researchers at The University of Queensland's (UQ) Centre for Immunology and Cancer Research (CICR), based at the Princess Alexandra Hospital, have pioneered a new approach for the treatment of cervical cancer. view more (2005-11-17)
Human embryonic stem cells display a unique pattern of chemical modification to DNA
Scientists from the Burnham Institute for Medical Research (BIMR) and Illumina Inc., in collaboration with stem cell researchers around the world, have found that the DNA of human embryonic stem cells is chemically modified in a characteristic, predictable pattern. view more (2006-08-07)
UC Riverside Researchers Discover Model Organism For Studying Viruses that Affect Humans
Researchers at the University of California, Riverside have discovered that a simple worm, called C. elegans, makes an excellent experimental host for studying some of the most virulent viruses that infect humans. view more (2005-08-18)
Bread mold may hold secret to eliminating disease-causing genes
When most people discover mold on their bread, they immediately throw it out. Others see a world of possibilities in the tiny fungus. A University of Missouri scientist, along with a collaborative research team, has examined a new mechanism in the reproductive cycle of a certain species of mold. view more (2008-05-09)
Montreal researchers probe the genetic basis of memory
A group of Montreal researchers has discovered that GCN2, a protein in cells that inhibits the conversion of new information into long-term memory, may be a master regulator of the switch from short-term to long-term memory. view more (2005-08-31)
UCR-led study identifies crucial mechanism involved in immune response against viruses
A research team led by UC Riverside scientists has shown that the common fruit fly can serve as an excellent model for studying the immunity animals are born with for fighting viral infections. view more (2006-03-24)
Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial
A molecular "off" switch packaged in a tiny sphere penetrates deeply into ovarian cancer tumor cells, stifling a troublesome protein and drastically reducing the size of tumors. view more (2006-08-15)
Silencing the cause of mad cow disease
BSE (more commonly known as mad cow disease) and CJD, which is a related disease in humans that can occur spontaneously, be inherited, or be acquired (in some cases probably from cows with BSE), are fatal neurodegenerative diseases. view more (2006-12-04)
Novel molecular 'signature' marks DNA of embryonic stem cells
A team of scientists announced today a critical step on the path of realizing the promise of embryonic stem (ES) cells for medicine. view more (2006-04-21)
Model identifies genes that induce normal skin cells to become abnormal
Northwestern University researchers have developed a novel, three-dimensional model that allows scientists to observe how interacting with the microenvironment of metastatic melanoma cells induces normal skin cells to become similar to aggressive cancer cells that migrate and spread throughout the body. view more (2005-11-15)
Researchers at Vanderbilt-Ingram Cancer Center uncover clue to explain invasive brain tumors
Researchers at the Vanderbilt-Ingram Cancer Center have uncovered a clue to explain the invasive nature of an aggressive kind of brain tumor called glioblastoma multiforme, or gliomas. view more (2006-01-12)
Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models
In mice, that had been genetically engineered to develop Alzheimer's disease, scientists were able to reverse the rodents' memory loss by reducing the amount of an enzyme that is crucial for the development of Alzheimer's disease. view more (2005-09-22)
Non-coding RNAs help silence the mammalian transcription
Dr. Shirley Tilghman and colleagues (Princeton University) lend new insight into the mechanism of genomic imprinting, demonstrating a necessary role for a non-coding RNA transcript in the silencing of an imprinted gene cluster in mice. view more (2006-05-15)
Making memories that last a lifetime
Neurobiologists have discovered a mechanism by which the constantly changing brain retains memories—from that dog bite to that first kiss. They have found that the brain co-opts the same machinery by which cells stably alter their genes to specialize during embryonic development. view more (2007-03-15)
Researchers find protein that silences genes
A team of researchers, including biologists at Washington University in St. Louis, has discovered the key role one protein plays in a major turn-off - in this case, the turning off of thousands of nearly identical genes in a hybrid plant. view more (2006-05-08)
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