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'Guardian of the genome' protein found to underlie skin tanning
A protein known as the "master watchman of the genome" for its ability to guard against cancer-causing DNA damage has been found to provide an entirely different level of cancer protection: By prompting the skin to tan in response to ultraviolet light from the sun, it deters the development of melanoma skin cancer, the fastest-increasing... view more... (2007-03-09)

Recurrent melanoma may be more common than previously thought
Approximately 8 percent of patients with melanoma skin cancer may develop an additional melanoma within two years of their initial diagnosis, and those with atypical moles appear to be at higher risk.   view more (2006-04-18)

Skin cancer rare - but more deadly - in people with darker skin
New research from the University of Cincinnati (UC) shows that dark-skinned people-commonly thought to be "immune" to most skin cancers-are more likely than whites to die from skin cancer and its related complications.   view more (2006-07-28)

Melanoma risk only partially associated vith exposure to UVB from sunlight
Researchers at The University of Texas M. D. Anderson Cancer Center have found that the risk of developing melanoma, the most deadly form of skin cancer, is only partially associated with exposure to ultraviolet B (UVB) radiation, the rays in sunlight that increase in summer and cause sunburn.   view more (2005-12-21)

New source of multipotent adult stem cells discovered in human hair follicles
Researchers at the University of Pennsylvania School of Medicine have isolated a new source of adult stem cells that appear to have the potential to differentiate into several cell types.   view more (2006-07-13)

Researchers discover why melanoma is so malignant
About 60,000 Americans will be diagnosed with melanoma this year, says the American Cancer Society, and 10,000 of those cases will be fatal.   view more (2005-09-06)

Researchers use embryonic model to reprogram malignant melanoma
Scientists at Northwestern University and the Stowers Institute for Medical Research have reprogrammed malignant melanoma cells to become normal melanocytes, or pigment cells, a development that may hold promise in treating of one of the deadliest forms of cancer.   view more (2006-02-28)

Why don't all moles progress to melanoma?
Everyone has moles. Most of the time, they are nothing but a cosmetic nuisance. But sometimes pigment-producing cells in moles called melanocytes start dividing abnormally to form a deadly form of skin cancer called melanoma.   view more (2006-10-03)

New insight into skin-tanning process suggests novel way of preventing skin cancer
Findings from a study led by researchers at Dana-Farber Cancer Institute and Children's Hospital Boston have rewritten science's understanding of the process of skin tanning - an insight that has enabled them to develop a promising way of protecting fair-skinned people from skin cancer caused by exposure to sunlight.   view more (2006-09-21)

Tanning Devices - Fast Track to Skin Cancer?
An all over tan is fashionable and large numbers of people, especially young women, achieve this by using sunbeds. Professor Antony Young, of King's College London, has reviewed the evidence that links sunbed use to malignant melanoma; a skin cancer that is fatal if not detected and treated early. Malignant melanoma is a cancer of the skin's cells... view more... (2004-01-15)

Scientists identify novel gene driving the growth and survival of melanoma cells
A team of researchers led by scientists at Dana-Farber Cancer Institute have discovered a genetic abnormality in the cells of some advanced melanoma patients that worsens their chances of survival, but also might be a target of future drug attack against the dangerous skin cancer.   view more (2005-07-07)

NYU researchers demonstrate activity of mebendazole in metastatic melanoma
Researchers at the NYU Cancer Institute and the Ronald O. Perelman Department of Dermatology have identified mebendazole, a drug used globally to treat parasitic infections, as a novel investigational agent for the treatment of chemotherapy-resistant malignant melanoma.   view more (2008-08-07)

New Technology To Help Early Skin Cancer Diagnosis
Computer scientists in the UK have invented a new technology to help doctors diagnose skin cancer while it is still in its early stages, greatly improving the chances of successful treatment. The work has been carried out by a team led by Dr Ela Claridge in the University of Birmingham's School of Computer Science. The Engineering and Physical... view more... (2000-04-11)

UBC researchers discover gene mutation that causes eye cancer
A University of British Columbia geneticist has discovered a gene mutation that can cause the most common eye cancer - uveal melanoma.   view more (2008-12-11)

Research Suggests New Options in Treating Skin Pigment Problems
Melanocytes are not the only cells responsible for differences in skin coloration. New research from the University of Cincinnati (UC) has shown that some of the most basic cells on the skin's surface influence pigment production and help regulate skin coloration.   view more (2007-08-23)

Function of key protein in Alzheimer's discovered
Scientists at the University of Bonn, working in collaboration with Italian researchers, have discovered the biological function of a protein normally associated with the onset of the Alzheimer's disease. Their results were published at the end of September in the US periodical "FASEB Journal", and the full-length report is already... view more... (2003-08-21)

Scientists create mouse model of melanoma that generates hope for the use of targeted therapies
Researchers have developed a new mouse model that allows them to replicate normal pigment cells at the earliest stages of conversion to malignant skin cancer in humans.   view more (2009-03-13)

New findings on the formation of body pigment
The skin's pigment cells can be formed from completely different cells than has hitherto been thought, a new study from the Swedish medical university Karolinska Institutet shows. The results, which are published in the journal Cell, also mean the discovery of a new kind of stem cell.   view more (2009-10-19)

Zebrafish provide a model for cancerous melanoma in humans
In a new study published in Disease Models & Mechanisms, scientists use the zebrafish to gain insight into the influence of known cancer genes on the development and progression of melanoma, an aggressive form of human skin cancer with limited treatment options.   view more (2009-05-26)

Novel epigenetic markers of melanoma may herald new treatments for patients
Melanoma is the most serious form of skin cancer, diagnosed in more than 50,000 new patients in the United States annually. While the rate of incidences continues to rise, survival rate has not improved and the race is on to find the genetic and cellular changes driving melanoma and to devise new means of detection and treatment.   view more (2009-06-30)
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