Most Viewed Methylation Current Events | Methylation News
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Human embryonic stem cells display a unique pattern of chemical modification to DNA
Scientists from the Burnham Institute for Medical Research (BIMR) and Illumina Inc., in collaboration with stem cell researchers around the world, have found that the DNA of human embryonic stem cells is chemically modified in a characteristic, predictable pattern. view more (2006-08-07)
Embryonic stem cells accrue genetic changes
An international team of researchers has discovered that human embryonic stem cell lines accumulate changes in their genetic material over time. view more (2005-09-06)
Making memories that last a lifetime
Neurobiologists have discovered a mechanism by which the constantly changing brain retains memories—from that dog bite to that first kiss. They have found that the brain co-opts the same machinery by which cells stably alter their genes to specialize during embryonic development. view more (2007-03-15)
Researchers find protein that silences genes
A team of researchers, including biologists at Washington University in St. Louis, has discovered the key role one protein plays in a major turn-off - in this case, the turning off of thousands of nearly identical genes in a hybrid plant. view more (2006-05-08)
Researchers find better prostate cancer indicators
Researchers at Mayo Clinic have narrowed the search for effective prostate cancer biomarkers (genetic variations that point to a specific disease or condition), identifying changes in the expression of genes of the whole genome closely correlated to prostate cancer development and progression. view more (2006-03-28)
Enzyme complex thought to promote cancer development can also help prevent it
In a case of basic science detective work, researchers at The University of Texas M. D. Anderson Cancer Center have solved the puzzle of the "inconsistent biomarker" and, in the process, may have discovered an agent that can suppress cancer development. view more (2005-10-14)
Change in gene may be underlying molecular defect in some colorectal cancers, study suggests
Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer. view more (2005-09-21)
Early estrogen exposure leads to later prostate cancer risk
A study in the June 1 issue of Cancer Research presents the first evidence that exposure to low doses of environmental estrogens during development of the prostate gland in the male fetus may result in a predisposition to prostate cancer later in life. view more (2006-06-01)
Researchers uncover new mechanism of tumor suppressor
Researchers from the University of Colorado-Denver and Health Sciences Center and Stanford University have discovered a molecular mechanism that explains how cells respond to DNA damage and other acute stresses, and if disrupted can cause cancer. view more (2006-05-22)
Genes offer researchers a 'crystal ball' to help them prevent, diagnose and treat cancer
The science of cancer prevention has advanced to the point where researchers now say they can detect "cancer genes" in the breath of smokers, and can test the presence of two proteins in men they say will predict development of prostate cancer a decade in advance. view more (2006-11-13)
Novel enzyme offers new look at male hormone regulation
For the second time in less than a year, University of North Carolina at Chapel Hill scientists have purified a novel protein and have shown it can alter gene activity by reversing a molecular modification previously thought permanent. view more (2006-05-08)
Cancer cells suppress large regions of DNA by a reversible process that can be tackled
Cancer researchers at Sydney's Garvan Institute, in collaboration with Spanish scientists, have formulated a new concept for how cancer cells can escape normal growth controls, which may have far-reaching implications for the new generation of cancer therapies. view more (2006-04-24)
USC study in Nature Genetics supports a stem cell origin of cancer
Researchers at the University of Southern California (USC) recently made significant strides toward settling a decades-old debate centering on the role played by stem cells in cancer development. view more (2007-01-10)
Regulating the Nuclear Architecture of the Cell
An organelle called the nucleolus resides deep within the cell nucleus and performs one of the cell's most critical functions: it manufactures ribosomes, the molecular machines that convert the genetic information carried by messenger RNA into proteins that do the work of life. view more (2006-12-11)
In a technical tour de force, Salk scientists take a global view of the epigenome
A collaboration between researchers at the Salk Institute for Biological Studies and the University of California at Los Angeles captured the genome-wide DNA methylation pattern of the plant Arabidopsis thaliana-the "laboratory rat" of the plant world-in one big sweep. view more (2006-09-01)
Depression model leaves mice with molecular scar
In addition to triggering a depression-like social withdrawal syndrome, repeated defeat by dominant animals leaves a mouse with an enduring "molecular scar" in its brain that could help to explain why depression is so difficult to cure. view more (2006-03-01)
Novel regulatory mechanism identified for key tumor suppressor p53
Collaborating scientists from The Wistar Institute in Philadelphia and The Vienna Biocenter in Austria have identified a novel mechanism involved in normal repression of the p53 protein, perhaps the single most important molecule for the control of cancer in humans. view more (2006-11-16)
Child abuse may 'mark' genes in the brains of suicide victims
A team of McGill University scientists has discovered important differences between the brains of suicide victims and so-called normal brains. Although the genetic sequence was identical in the suicide and non-suicide brains, there were differences in their epigenetic marking - a chemical coating influenced by environmental factors. view more (2008-05-07)
Cells in mucus from lungs of high-risk patients can predict tumor development
n a group of high-risk patients, a test that examined DNA from cells expelled in sputum for evidence of "silenced" genes correctly identified the majority of patients who were later diagnosed with lung cancer. view more (2006-03-15)
Profiling of cancer genes may lead to better and earlier detection
A research team at UT Southwestern Medical Center has for the first time identified several genes whose expression is lost in four of the most common solid human cancers - lung, breast, prostate and colon cancer. view more (2006-12-27)
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