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MicroRNA tweaks protein that controls early heart development Researchers at UT Southwestern Medical Center have discovered how a small molecule of RNA called microRNA - a chemical cousin of DNA - helps fine tune the production of a key protein involved in the early development of heart muscle. view more (2005-06-13)
microRNA-mediated metabolism In the February 15th issue of G&D, Drs. Aurelio Teleman and Stephen Cohen (EMBL) assign one of the first biological functions to an animal microRNA: the microRNA miR-278 regulates energy homeostasis in Drosophila. view more (2006-02-15)
Stanford scientist to discuss new approach to treating hepatitis C virus Last year Peter Sarnow, PhD, professor of microbiology and immunology at the Stanford University School of Medicine, identified a previously unknown mechanism that the hepatitis C virus uses to replicate, yielding a promising new approach to combating the disease-causing virus. view more (2006-04-06)
MicroRNAs play a big part in gene regulation-and evolution egulating when and where certain proteins are made is crucial to the normal functioning of living things. To make proteins, information from DNA is transcribed into RNA molecules and then translated into the amino acids building blocks of proteins. view more (2005-06-24)
Tiny RNA molecules fine-tune the brain's synapses Non-coding regions of the genome - those that don't code for proteins - are now known to include important elements that regulate gene activity. view more (2006-01-19)
MicroRNA may have fail-safe role in limb development A tiny strand of molecules plays a role in how our arms and legs develop and grow-a finding that sheds light on perplexing bits of material once dismissed as genetic "junk," say scientists at the University of Florida and Harvard University. view more (2005-12-02)
Study establishes new class of cancer-causing genes Over the past few years, scientists have discovered that a new class of genetic regulators called "microRNAs" influences normal human growth and development. Now, researchers have found that microRNAs also play an important role in human cancer. view more (2005-06-08)
Biologists develop genome-wide map of miRNA-mRNA interactions Researchers at New York University's Center for Comparative Functional Genomics and the University of California, Berkeley have used computational analyses to predict a genome-wide map of microRNA (miRNA) targets in the animal model organism, Caenorhabditis elegans (C. elegans). view more (2006-03-09)
MicroRNA processing and cancer In an upcoming G&D paper, Dr. Scott Hammond (UNC-Chapel Hill) and colleagues describe a key regulatory step during microRNA biogenesis, which may underlie alterations of microRNA expression in cancer. view more (2006-08-01)
Renegade RNA — Clues to cancer and normal growth Researchers at Johns Hopkins have discovered that a tiny piece of genetic code apparently goes where no bit of it has gone before, and it gets there under its own internal code. view more (2007-01-05)
Xie Lab demonstrates the role of microRNA pathway Ting Xie, Ph.D., Associate Investigator, and Zhigang Jin, Ph.D., Postdoctoral Research Associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary. view more (2007-02-16)
Flip-Flopped Chromosome Reveals a First Clue to Tourette Syndrome Researchers have identified the first gene mutation associated with Tourette syndrome-opening a new avenue for understanding the complex disorder that causes muscle and vocal tics. view more (2005-10-14)
UF scientists identify cancer virus' genetic targets University of Florida researchers have identified specific human genes targeted by a virus believed to cause Kaposi's sarcoma, a rare form of cancer associated with AIDS and with organ transplants that causes patches of red or purple tissue to grow under people's skin. view more (2007-05-11)
New biomarkers for lupus found A Wake Forest University School of Medicine team believes it has found biomarkers for lupus that also may play a role in causing the disease. view more (2006-11-13)
MicroRNAs have shaped the evolution of the majority of mammalian genes RNA continues to shed its reputation as DNA's faithful sidekick. Now, researchers in the lab of Whitehead Institute Member David Bartel have found that a class of small RNAs called microRNAs influence the evolution of genes far more widely than previous research had indicated. view more (2005-11-30)
MicroRNA gene that regulates lifespan found by Yale scientists Genes that control the timing of organ formation during development also control timing of aging and death, and provide evidence of a biological timing mechanism for aging, Yale researchers report in the journal Science. view more (2005-12-23)
MicroRNA helps prevent tumors A microRNA directly regulates a gene implicated in human cancers, researchers from Whitehead Institute and Massachusetts Institute of Technology report in the February 22nd online issue of Science. view more (2007-02-23)
Tiny molecule controls stress-induced heart disease A tiny snippet of RNA, a chemical cousin of DNA, controls damage to the heart under several types of stress, researchers at UT Southwestern Medical Center have found. view more (2007-03-23)
How body size is regulated: International study discovers ten new genes related to human growth Scientists are beginning to unravel the question why people distinctly vary in size. view more (2008-05-12)
Pair of microRNA molecules controls major oncogene in most common leukemia Researchers at Ohio State University have discovered that two microRNA (miRNA) molecules help control the oncogene responsible for a dangerous form of B-cell chronic lymphocytic leukemia (B-CLL), the most common human leukemia in the world. view more (2006-12-18)
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