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DNA that controls the malaria parasite's disguise mechanism
Professor Alan Cowman, Dr Brendan Crabb and their research teams at WEHI have identified how the most lethal malaria parasite, Plasmodium falciparum, is able to disguise itself from the human immune system.   view more (2006-01-04)

Beyond genes: Lipid helps cell wall protein fold into proper shape
A protein that provides a vital passage through a bacterium's outer cell wall will misfold and malfunction if that wall is built of the 'wrong' material, scientists at The University of Texas Medical School at Houston report in a finding that has long-term implications for understanding diseases... view more (2005-07-18)

Small molecule offers big hope against cancer
DCA is an odourless, colourless, inexpensive, relatively non-toxic, small molecule. And researchers at the University of Alberta believe it may soon be used as an effective treatment for many forms of cancer.   view more (2007-01-17)

Scientists discover how gold eases pain of arthritis
Scientists at Duke University Medical Center may have solved the mystery surrounding the healing properties of gold - a discovery they say may renew interest in gold salts as a treatment for rheumatoid arthritis and other inflammatory diseases.   view more (2007-10-23)

Tetanus toxin found to have therapeutic properties
A team of researchers from the Department of Biochemistry and Molecular Biology and the Institute of Neuroscience at the Universitat Autònoma de Barcelona has discovered that tetanus toxin, which causes tetanus, could be extremely useful as a therapy against psychological disorders... view more (2005-06-15)

Cell's fight against cancer revealed
If anything in cancer biology can be likened to a cage match, this is it: the battle inside the cell walls between LTag, "The Most Amazing Molecule in the Universe," and p53, "The Guardian of the Genome."   view more (2006-09-01)

Genetically engineered blood protein can be used to split water into oxygen and hydrogen
Scientists have combined two molecules that occur naturally in blood to engineer a molecular complex that uses solar energy to split water into hydrogen and oxygen.   view more (2006-12-01)

Cell wall of pneumonia bacteria can cause brain and heart damage
Investigators at St. Jude Children's Research Hospital have discovered in mouse models how cell walls from certain pneumonia-causing bacteria can cause fatal heart damage; researchers have also shown how antibiotic therapy can contribute to this damage by increasing the number of cell wall pieces... view more (2006-10-25)

Scientists one step closer to cancer vaccine
Scientists at Karolinska Institutet in Sweden have helped to identify a molecule that can be used as a vaccination agent against growing cancer tumours.   view more (2006-03-22)

Physics and biology team up to tackle protein folding debate
A team of researchers from EPFL, (Ecole Polytechnique Fédérale de Lausanne), the University of Lausanne, Northwestern University and Tel Aviv University bring biology and statistical physics together to answer the question of how molecular chaperones fold, unfold and pull proteins... view more (2006-04-04)

Killing brain tumors from within: A 'Trojan horse' approach
A new method for targeting malignant brain tumors through inducing the cancerous cells to "commit suicide" has been developed by a team of researchers headed by a Hebrew University of Jerusalem professor of biochemistry.   view more (2006-10-25)

Hydrogen bonds shown to play 'conserved' role in protein folding
By changing individual atoms in key places in proteins, Duke University chemists have found new evidence for the importance of comparatively weak "hydrogen bonds" in enabling stringlike proteins to fold into the maximally stable shape they need to assume their roles as biological... view more (2006-02-13)

Researchers find molecule that inhibits regrowth of spinal nerve cells
A molecule that helps the body's motor nerve cells grow along proper paths during embryonic development also plays a major role in inhibiting spinal-cord neurons from regenerating after injury, researchers at UT Southwestern Medical Center have found.   view more (2005-07-12)

Waking a sleeping virus
A detailed structural picture of a molecule that plays a key role in activating the Epstein Barr Virus in human cells has now been obtained by researchers at the European Molecular Biology Laboratory (EMBL) and the Institut de Virologie Moléculaire et Structurale (IVMS), associated with... view more (2006-02-17)

Small molecule interactions were central to the origin of life
In an important new paper forthcoming in the June issue of The Quarterly Review of Biology, Robert Shapiro (New York University) argues against the widely held theory that the origin of life began with the spontaneous appearance of a large, replicating molecule such as RNA.   view more (2006-05-17)

Seismologists detect a sunken slab of ocean floor deep in the Earth
Halfway to the center of the Earth, at the boundary between the core and the mantle, lies a massive folded slab of rock that once formed the ocean floor and sank beneath North America some 50 million years ago.   view more (2006-05-18)

Study finds protein is required for human chromosome production
Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified an elusive protein that performs a necessary step in the production of human chromosomes.   view more (2005-10-13)

Scientists capture the speediest ever motion in a molecule
The fastest ever observations of protons moving within a molecule open a new window on fundamental processes in chemistry and biology, researchers report today in the journal Science.   view more (2006-03-03)

Metal-containing compounds show promise as HIV weapon
A molecule consisting of two "cages" of metallic atoms bound to carbon has shown great promise in preliminary tests of becoming a new weapon in the anti-HIV arsenal, researchers at UT Southwestern Medical Center report.   view more (2005-11-01)

Accelerated evolution converts RNA enzyme to DNA enzyme in vitro
This 'evolutionary conversion' provides a modern-day snapshot of how life as we understand it may have first evolved out of the earliest primordial mix of RNA-like molecules-sometimes referred to as the "pre-RNA world"-into a more complex form of RNA-based life (or the "RNA... view more (2006-03-28)

Key heart and Alzheimer's disease protein imaged for first time in native state
Researchers for the first time have created a three-dimensional image of apolipoprotein E, a protein long associated with cardiovascular disease and more recently with Alzheimer's disease, as it appears when it is bound to fat-like substances known as lipids.   view more (2006-01-16)

Specific treatments for each type of sarcoma
The new molecular techniques allow designing specific treatments for a great number of sarcomas, according to Dr. Enrique de Alava, expert of the department of Pathologic Anatomy of the University Clinic of the University of Navarre. The molecular knowledge has become a very useful tool to study... view more (2002-11-29)

In chemical genetics, a new strategy could speed drug discovery
Researchers at Fox Chase Cancer Center have developed a new technique to speed discovery of drug targets in chemical genetics. As highlighted on the April cover of Chemistry & Biology, Fox Chase researcher Jeffrey R. Peterson, Ph.D., and his colleagues describe a new way to swiftly find the... view more (2006-04-24)

DNA size a crucial factor in genetic mutations, study finds
Researchers at Stanford University have created a larger-than-normal DNA molecule that is copied almost as efficiently as natural DNA.   view more (2005-10-27)

Free-energy theory borne out in large-scale protein folding
In unprecedented new research, scientists at Rice University have combined theory and experiment for the first time to both predict theoretically and verify experimentally the protein-folding dynamics of a large, complex protein.   view more (2005-10-04)
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