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REVLIMID improves overall survival and delays disease progression in multiple myeloma patients
Celgene Corporation (NASDAQ: CELG) announced updated clinical data from two Phase III pivotal studies evaluating REVLIMID (lenalidomide) plus dexamethasone in previously treated multiple myeloma patients.   view more (2005-12-13)

Thalidomide treatment proves better than conventional chemotherapy for multiple myeloma
When people hear "thalidomide," many think "birth defects," however, evidence has come to light that this once-banned drug can be used as a potent anti-cancer treatment. In a new study, researchers from the University of Bologna, Italy, demonstrate that Thal-Dex (thalidomide used in combination with dexamethasone) is more... view more... (2005-06-21)

Rapid restoration of immunity in immune-suppressed cancer patients using T-cell vaccines
Patients with multiple myeloma suffer from a malignant proliferation of plasma cells in their bone marrow.   view more (2005-10-21)

Cell-regulating gene may predict survival outcomes for breast cancer patients
A study led by researchers at Mount Sinai School of Medicine has shown that a cell-regulating gene overexpressed in about 30 to 50 percent of all breast cancers is associated with a better chance of survival and increased sensitivity to a cancer-fighting drug.   view more (2006-09-06)

Building stronger bones, 1 stem cell at a time
Mesenchymal stem cells (MSCs) are bone marrow-derived cells that are capable of giving rise to various cell types through a process known as differentiation.   view more (2008-01-25)

Mayo Clinic Cancer Center — individualizing treatment for multiple myeloma patients
Researchers at Mayo Clinic Cancer Center, in cooperation with industry partners, have, for the first time, identified tumor specific alterations in the cellular pathway by which the multiple myeloma drug bortezomib (Velcade) works, and they have identified nine new genetic mutations in cancer cells that should increase a patient's chance of... view more... (2006-12-11)

Firefighters face increased risk for certain cancers
University of Cincinnati (UC) environmental health researchers have determined that firefighters are significantly more likely to develop four different types of cancer than workers in other fields.   view more (2006-11-10)

Promising advance in breast cancer research
Two new drugs, when combined, killed up to 75 percent of breast cancer tumor cells in mice and suppressed the regrowth of tumors, according to researchers at the Virginia Commonwealth University Massey Cancer Center.   view more (2005-11-15)

Keeping cancer at bay: Long-term therapy in the fight against multiple myeloma
There is no known cure for multiple myeloma, so its diagnosis means high-dose chemotherapy followed by repeated treatments with each relapse of the cancer - a watch and wait approach.   view more (2006-11-06)

Mayo Clinic research shows promise for myeloma patients
Mayo Clinic Cancer Center investigators report that combination therapy with lenalidomide (RevlimidTM) and dexamethasone (combination is called Rev/Dex) looks like a breakthrough treatment for multiple myeloma.   view more (2005-09-02)

Oral Drug Sets a New Survival Standard for Bone Marrow Cancer
Findings from two large, international clinical trials show "unprecedented" survival for patients with multiple myeloma, a blood cancer that occurs in the blood-making cells of bone marrow.   view more (2007-11-26)

Scientists discover new genetic subtypes of common blood cancer
Scientists at Dana-Farber Cancer Institute and collaborators have identified four distinct genetic subtypes of multiple myeloma, a deadly blood cancer, that have different prognoses and might be treated most effectively with drugs specifically targeted to those subtypes.   view more (2006-04-11)

An advanced genetic diagnostic method for multiple myeloma
A researcher at the University of Navarra, Borja Sáez Ochoa, has proposed a new genetic diagnostic method for multiple myeloma (MM), a type of bone marrow cancer, which permits the detection of this disease in earlier stages.   view more (2006-09-12)

Drug combination slows progression of treatment resistant bone marrow cancer
Combining a newly formulated drug with one that is already a standard treatment slows the progression of multiple myeloma, an advanced cancer of the bone marrow cells.   view more (2006-12-13)

Daisies lead scientists down path to new leukemia drug
A new, easily ingested form of a compound that has already shown it can attack the roots of leukemia in laboratory studies is moving into human clinical trials, according to a new article by University of Rochester investigators in the journal, Blood.   view more (2007-10-03)

New hope for patients with chronic lymphocytic leukemia
Patients treated with lenalidomide for relapsed chronic lymphocytic leukemia (CLL) or disease that no longer responds to chemotherapy have experienced a major response to therapy, according to a phase II study conducted by Asher Chanan-Khan, MD, Department of Medicine, Roswell Park Cancer Institute (RPCI). The results are published in the December... view more... (2006-12-05)

Stem cells make bone marrow cancer resistant to treatment
Scientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that cancer stem cells for multiple myeloma share many properties with normal stem cells and have multiple ways of resisting chemotherapy and other treatments.   view more (2008-01-14)

Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer
Mayo Clinic Cancer Center has opened a new clinical study using a vaccine strain of the measles virus to attack recurrent glioblastoma multiforme, a largely untreatable brain tumor. This is the second of several pending molecular medicine studies in patients using measles to kill cancer.   view more (2006-10-31)

Mayo Clinic researchers enhance safety and effectiveness of therapeutic virus that fights cancer
Mayo Clinic researchers working with colleagues in Germany have devised a much-needed multilevel safety feature for viruses used to treat cancer.   view more (2006-08-01)

Genome changes tracked during multiple myeloma initiation, progression and treatment
Scientists have made significant progress toward elucidating key genetic events associated with the development and progression of multiple myeloma (MM), an incurable malignancy that is the second most common cancer of the blood.   view more (2006-04-11)
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