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Elevated testosterone kills nerve cells
A Yale School of Medicine study shows for the first time that a high level of testosterone, such as that caused by the use of steroids to increase muscle mass or for replacement therapy, can lead to a catastrophic loss of brain cells.   view more (2006-09-27)

Nanotubes used for first time to send signals to nerve cells
Texas scientists have added one more trick to the amazing repertoire of carbon nanotubes - the ability to carry electrical signals to nerve cells.   view more (2006-05-09)

Stem cells as cancer therapy
It is widely hoped that neural stem cells will eventually be useful for replacing nerves damaged by degenerative diseases like Alzheimer disease and multiple sclerosis. But there may also be another use for such stem cells-delivering anti-cancer drugs to cancer cells.   view more (2006-12-26)

Cancer researchers describe gene that halts spread of aggressive childhood cancer
A team of cancer researchers has shown that a gene commonly lost during neuroblastoma tumor formation, one of the most aggressive cancers in babies and children, is in fact a "metastasis suppressor" gene.   view more (2006-01-05)

Researchers find stem-cell therapy effective in targeting metastatic cancer
Patients with advanced cancer that has spread to many different sites often do not have many treatment options, since they would be unable to tolerate the doses of treatment they would need to kill the tumors.   view more (2006-12-21)

Loss of caspase-8 makes neuroblastoma more aggressive
The caspase-8 gene plays a critical role in suppressing metastasis (spread) of neuroblastoma, and the expression of this gene is frequently absent in cancer cells that are aggressively metastasizing.   view more (2006-01-06)

Children's National researchers develop novel anti-tumor vaccine
A novel anti-tumor vaccine for neuroblastoma and melanoma developed by scientists and clinicians at Children's National Medical Center in collaboration with investigators from the University of Iowa is showing significant impact on tumor growth in mice.   view more (2008-10-03)

Antibody therapy promising for pediatric neuroblastoma
A new strategy that turns small populations of immune system cells into armies that track down and kill neuroblastoma throughout the body could save the lives of many children each year.   view more (2005-12-21)

St. Jude defines eye cancer gene's role in retinal development
A genetic discovery led by scientists at St. Jude Children's Research Hospital helps answer a long-standing mystery about the eyes of vertebrates, and may translate into a deeper understanding of how genes coordinate the complex process of eye formation and how a rare pediatric eye cancer progresses.   view more (2008-01-17)

Researchers use poliovirus to destroy neuroblastoma tumors in mice
The cause of one notorious childhood disease, poliovirus, could be used to treat the ongoing threat of another childhood disease, neuroblastoma.   view more (2007-03-16)

Breaking the medical image communication barrier
Using a new grid computing system, radiologists, physicians and pediatric oncologists at 40 hospitals all over North America are now quickly and securely exchanging high-resolution medical images.   view more (2006-11-27)

3 proteins may play important role in nerve-cell repair
Some mature brain cells can grow new extensions when the amount of three particular proteins on their surface increases, a new study shows.   view more (2007-04-12)

St. Jude shows gene test not needed if cancer drug given in low doses
Investigators at St. Jude Children's Research Hospital have shown that when the cancer drug irinotecan is given in low doses for multiple days, it eliminates the need to delay treatment to perform costly genetic testing that determines if the patient is at risk for serious treatment side effects, such as neutropenia.   view more (2007-06-20)

Tumor-targeting viral therapy slows neuroblastoma, malignant peripheral nerve sheath tumors
Researchers in a multi-institutional study led by Cincinnati Children's Hospital Medical Center slowed the growth of two particularly stubborn solid tumor cancers - neuroblastoma and peripheral nerve sheath tumors -without harming healthy tissues by inserting instructions to inhibit tissue growth into an engineered virus.   view more (2008-02-15)

Plant pathogen yields substance to fight neuroblastoma
Drug treatment of neuroblastoma, a tumor of the nervous system in children, poses major problems. Therefore, scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have been searching for substances that are suitable as a basis for developing better drugs. Now they have found a candidate: HC-toxin, which is... view more... (2008-01-18)

What change does prokineticin 2/Bv8 have in human hepatocellular carcinoma?
Liver hepatocarcinoma is a highly vascularized cancer, and more and more research is focused on the molecules controlling angiogenesis.   view more (2008-03-18)

New insight into the genetics of brain tumor formation
In a G&D paper published online ahead of its April 1 print publication date, Dr. William Kaelin (Dana Farber Cancer Institute) and colleagues identify a potential new neuronal tumor suppressor.   view more (2008-03-18)

EUROCARE-3 publishes new childhood cancer survival figures
The Nordic countries of Sweden, Norway, Finland and Iceland, represent a gold standard for the treatment of children's cancer. They have survival rates to which all European countries that devote similar resources and have comparable health systems can aspire, according to research published today (18 December 2003) in Annals of Oncology[1]. The... view more... (2003-12-16)

Neuroblastoma expert reviews progress and challenges in fighting difficult pediatric cancer
Childhood cancers are fortunately rare, but among them, neuroblastoma is a special case, accounting for 7 percent of all childhood cancers, but 15 percent of childhood cancer deaths.   view more (2007-06-25)

Scientists close in on method to fight deadly childhood cancer
A multicenter team of researchers, including scientists from the University of Florida, has discovered a way to potentially block the growth of neuroblastoma, a type of cancer responsible for 15 percent of all cancer deaths in children.   view more (2008-10-16)
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