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Disease-causing protein protects against nerve damage in Parkinson's disease
Researchers at UT Southwestern Medical Center have discovered that a protein associated with causing neurodegenerative conditions may, when appearing in normal amounts, actually protect against neurodegeneration.   view more (2005-11-04)

Study implicates potassium channel mutations in neurodegeneration and mental retardation
For the first time, researchers have linked mutations in a gene that regulates how potassium enters cells to a neurodegenerative disease and to another disorder that causes mental retardation and coordination problems.   view more (2006-02-27)

Study links Alzheimer's disease to abnormal cell division
A new study in mice suggests that Alzheimer's disease (AD) may be triggered when adult neurons try to divide. The finding helps researchers understand what goes wrong in the disease and may lead to new ways of treating it.   view more (2006-01-18)

A probable cause for Parkinson's?
Parkinson's, Alzheimer's, Lou Gehrig's disease and other brain disorders are among a growing list of maladies attributed to oxidative stress, the cell damage caused during metabolism when the oxygen in the body assumes ever more chemically reactive forms.   view more (2006-06-28)

Age-related memory improvement linked with consumption of apple products
New research from the University of Massachusetts Lowell suggests that consuming apple juice may protect against cell damage that contributes to age-related memory loss, even in test animals that were not prone to developing Alzheimer's disease and other dementias.   view more (2006-01-25)

New compound reduces stroke damage
A group of German scientists has synthesized a new compound that dramatically decreases the damage to neurons in rats demonstrating stroke symptoms.   view more (2006-05-16)

Reduced insulin in the brain triggers Alzheimer's degeneration
By depleting insulin and its related proteins in the brain, researchers at Rhode Island Hospital and Brown Medical School have replicated the progression of Alzheimer's disease - including plaque deposits, neurofibrillary tangles, impaired cognitive functioning, cell loss and overall brain... view more (2006-03-23)

Receptor critical in neurodegeneration reduces Alzheimer's plaque
Increasing the level of a protein that plays a key role in traumatic spinal cord injuries and multiple sclerosis reduces the concentration of disease-causing plaque in Alzheimer's disease.   view more (2006-02-03)

Scientists discover possible link between oxidative stress and non-hereditary degenerative disease
The irreversible neurological degeneration associated with Parkinson's and Alzheimer's diseases may be the consequence of oxidative stress-the imbalance of antioxidants and pro-oxidants in cells.   view more (2006-04-28)

Study ties 'new' cell-death mechanism to developmental and degenerative brain disorders
An international research team has provided the first conclusive evidence that neurodevelopmental disorders such as mental retardation and neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and ataxias can be caused, at least in part, by specific gene defects that... view more (2006-02-28)

Insulin receptor stops progression of Alzheimer's disease
Stimulation of a receptor in the brain that controls insulin responses has been shown to halt or diminish the neurodegeneration of Alzheimer's disease, providing evidence that the disease can be treated in its early stages.   view more (2006-09-22)

Untangling a pathology of Alzheimer's
Researchers have uncovered what appears to be a natural protective mechanism against a central cause of neuronal death in Alzheimer's and similar neurodegenerative diseases.   view more (2006-09-07)

New mechanism found for neurodegenerative effects of amphetamines in mice
University of Toronto researchers have discovered a new mechanism for the neurodegenerative effects of amphetamines.   view more (2006-04-06)

Transcription factor protein's role in cell death, neurodegeneration and schizophrenia
Researchers at the University of Pennsylvania School of Medicine discovered that a protein called Elk-1 interacts with mitochondria, the energy storehouse of a cell, suggesting that this protein -— typically active in the nucleus — could play a role in cell death and... view more (2006-06-08)

WHAT FUTURE FOR CANNABIS?
The potential therapeutic effects of cannabis are outlined in a review in the May issue of THE LANCET NEUROLOGY. The review is published in anticipation of results from randomised trials expected later this year investigating possible benefits of the drug for people with multiple sclerosis. The... view more (2003-04-16)

3-D forms link antibiotic resistance and brain disease
The story of what makes certain types of bacteria resistant to a specific antibiotic has a sub-plot that gives insight into the cause of a rare form of brain degeneration among children, according to investigators at St. Jude Children's Research Hospital.   view more (2006-08-21)

Scientists link another gene to degenerative blindness
Researchers have labored for decades to understand blindness-inducing neurodegenerative diseases such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP).   view more (2006-01-19)

Cell death in sparrow brains may provide clues in age-related human diseases
A remarkable change takes place in the brains of tiny songbirds every year, and some day the mechanism controlling that change may help researchers develop treatments for age-related degenerative diseases of the brain such as Parkinson's and dementia.   view more (2007-09-18)

Rare disease's gene may illuminate major disorders
Oregon Health & Science University researchers have identified the gene behind a group of rare, progressive childhood disorders caused by an abnormal buildup of iron in the brain.   view more (2006-06-19)

Research suggests cause of neurodegeneration in Huntington's disease
The severe neurodegeneration associated with Huntington's disease may result from molecular mutations that block the transport of nutrients within cells.   view more (2006-05-31)

Mechanism for neurodenegerative diseases linked to transport proteins
Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, ALS and Kennedy disease. Understanding how this cell transport is blocked in these diseases may offer targets for future therapy.   view more (2006-06-09)

Scientists close in on genes responsible for Parkinson's disease
Scientists have identified 570 genes that act abnormally during the development of Parkinson's Disease, a finding which could help doctors predict the likelihood of it developing, and provide targets for new treatments.   view more (2005-12-20)

Finding a cellular Neverland: How stem cells stay childlike
espite their celebrated "immortality," the capacity of embryonic stem (ES) cells for endless division has its limits. After a very extended childhood spent dividing in a culture dish, even stem cells tend to grow up and assume adult roles as workaday nerve, muscle, or blood cells, never... view more (2006-06-27)

Top-rung research environments singled out
A panel of acknowledged international experts has identified Sweden's foremost environments for basic research. The Swedish Research Council will be able to finance ten of the 27 research environments of excellence that have been winnowed from 261 applications. These research teams are from all... view more (2005-02-17)

Discoveries should aid research into cause of ALS
Two teams of researchers at Northwestern University have found a novel pathological hallmark of the neurodegenerative disease amyotrophic lateral sclerosis (ALS) at the molecular level.   view more (2006-04-26)
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