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Mosquito immune system examined
Mosquitoes employ the same immune factors to fight off bacterial pathogens as they do to kill malaria-causing Plasmodium parasites, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health. view more (2006-06-09)
Gene that helps mosquitoes fight off malaria parasite identified
Researchers have identified a gene in mosquitoes that helps the insects to fight off infection by the Plasmodium parasite, which causes malaria in humans. Anopheles mosquitoes transmit the malaria parasite to nearly 550 million people worldwide each year with these cases resulting in more than 2 million deaths annually. view more (2005-10-25)
Sugar identified as key to malaria parasite invasion
Researchers at the Johns Hopkins Malaria Research Institute (JHMRI) have identified a sugar in mosquitoes that allows the malaria-causing parasite, Plasmodium falciparum, to attach itself to the mosquito's gut. view more (2007-09-11)
Malaria Parasites Develop in Lymph Nodes
In the first quantitative, real-time imaging study of the travels of the malaria parasite Plasmodium through mammalian tissue, researchers at the Pasteur Institute in Paris found the parasites developing in an unexpected place: the lymph nodes. view more (2006-01-23)
Malaria : Plasmodium togetherness a strategy for breeding success
Malaria, which infects 600 million people in the world and leads annually to 2 million deaths, is the most widespread of infectious diseases. The pathological agent is a microscopic parasite of the Plasmodium genus which develops inside the host's erythrocytes. Plasmodia go through a series of asexual reproduction cycles before a transition takes... view more... (2004-02-20)
PATH Malaria Vaccine Initiative announces partnership to develop novel malaria vaccine
In a move that promises to expand the types of malaria vaccine candidates in clinical development, the PATH Malaria Vaccine Initiative (MVI) today announced a new partnership with Sanaria Inc., a Maryland company, to accelerate development of a unique malaria vaccine candidate. view more (2006-12-18)
Scientists demonstrate feasibility of preventing malaria parasite from becoming sexually mature
Researchers have demonstrated the possibility of preventing the human malaria parasite, Plasmodium falciparum, which is responsible for more than a million malaria deaths a year, from becoming sexually mature. view more (2008-06-03)
Malaria mechanism revealed
By determining the molecular structure of a protein that enables malaria parasites to invade red blood cells, researchers have uncovered valuable clues for rational antimalarial drug design and vaccine development. view more (2005-07-29)
Possible new compound for treatment of cerebral malaria
In a paper published online in PLoS Medicine researchers from Marseille describe the effects of a new compound that may be a future treatment for patients with cerebral malaria. view more (2005-08-23)
Passenger Screening Advised To Cut Risk Of Importing Drug-Resistant Malaria To Africa
Imported resistance has rendered ineffective the two affordable malaria drugs which have been the mainstay of malaria treatment in Africa for forty years, according to experts writing today in the journal Science. Scientists from the London School of Hygiene and Tropical Medicine and colleagues from institutions in the USA, South Africa and... view more... (2004-08-16)
Tracking membranes of rupturing blood cells sheds light on malaria infection
By specially tagging the outer and inner membranes of red blood cells infected with the malaria parasite and tracking the cellular changes that precede the cell bursting event that disperses parasites to other blood cells, a group of researchers has deepened our understanding of how the malaria pathogen destroys the cells in which it resides. view more (2005-09-22)
Antibody-based therapies effective at controlling malaria
Passive immunization through the development of fully human antibodies specific to Plasmodium falciparum may be effective at controlling the disease, report researchers led by Dr. Richard S. McIntosh from the University of Nottingham in a paper published this week in the open-access journal PLoS Pathogens. view more (2007-05-18)
Binghamton University researchers investigate evolving malaria resistance
Funded by a $1.5 million grant from the National Institutes of Health, scientists at Binghamton University, State University of New York, hope to understand how the malaria parasite Plasmodium falciparum evolved resistance to the once-effective medication chloroquine. view more (2007-08-30)
Could malaria return to the UK?
Millions of tourists now travel between the UK and countries where malaria is endemic. Given this, entomologists from the University of Durham are to undertake a thorough risk assessment of malaria returning to the UK. Speaking at the Royal Entomological Society’s meeting Entomology 2001: “Insects and disease”, to be held at the... view more... (2001-08-30)
Bug-Zapper: A dose of radiation may help knock out malaria
How are physicists helping an effort to eradicate malaria, the mosquito-borne disease that kills more than one million people every year" Researchers at the National Institute of Standards and Technology (NIST) used their expertise in radiation science to help a young company create weakened, harmless versions of the malaria-causing parasite. view more (2007-11-09)
Certain combination therapy found more effective for treating malaria in African children
Ugandan children who received the combination therapy of artemether-lumefantrine experienced a lower rate of treatment failure compared to other combination therapies, according to a study in the May 23/30 issue of JAMA, a theme issue on malaria. view more (2007-05-23)
Genetic map offers new tool for malaria research
An international research team announced today the completion of a genome-wide map that charts the genetic variability of the human malaria parasite Plasmodium falciparum. view more (2006-12-11)
Researchers discover how malaria parasite disperses from red blood cells
Researchers at the National Institute of Child Health and Human Development have determined the sequence in which the malaria parasite disperses from the red blood cells it infects. view more (2005-09-20)
Malaria-resistant mosquitoes battle disease with 'molecular warhead'
A team led by UT Southwestern Medical Center researchers has discovered why some mosquitoes are resistant to malaria, a finding that may one day help fight a disease that afflicts and kills millions of people. view more (2007-07-09)
'GreeneChip' — New diagnostic tool that rapidly and accurately identifies multiple pathogens
Researchers in the Greene Infectious Disease Laboratory at Columbia University Mailman School of Public Health and their colleagues in the WHO Global Laboratory Network have developed a new tool for pathogen surveillance and discovery-the GreeneChip System. view more (2006-12-06)
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