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Penn Scientists Use RNA to Reprogram One Cell Type into Another For the past decade, researchers have tried to tweak cells at the gene and nucleus level to reprogram their identity. Now, working on the idea that the signature of a cell is defined by molecules called messenger RNAs, which contain the chemical blueprint for how to make a protein, researchers at the University of Pennsylvania School of Medicine,... view more... (2009-04-17)
MicroRNA in human saliva may help diagnose oral cancer Researchers continue to add to the diagnostic alphabet of saliva by identifying the presence of at least 50 microRNAs that could aid in the detection of oral cancer, according to a report in Clinical Cancer Research, a journal of the American Association for Cancer Research. view more (2009-08-26)
Gene mutation increases drug toxicity, rejection risk in pediatric kidney transplants Screening for mutations in a gene that helps the body metabolize a kidney transplant anti-rejection drug may predict which children are at higher risk for side effects, including compromised white blood cell count or organ rejection, according to new research. view more (2009-02-18)
Locking Parasites in Host Cell Could Be New Way to Fight Malaria, Penn Study Shows Researchers at the University of Pennsylvania have discovered that parasites hijack host-cell proteins to ensure their survival and proliferation, suggesting new ways to control the diseases they cause. view more (2009-04-06)
Nanoresearchers challenge dogma in protein transportation in cells New data on signalling proteins, called G proteins, may prove important in fighting diseases such as cardiovascular, neurodegenerative disorders, and cancer. view more (2009-09-22)
Researchers gain ground in efforts to fight parasite infection New findings by researchers UT Southwestern Medical Center are accelerating efforts to eradicate worm infections that afflict a third of the world's population. view more (2009-05-27)
Pregnant women at high risk of complications from H1N1 influenza With the H1N1 flu outbreak now elevated to pandemic level, a new article in CMAJ (Canadian Medical Association Journal) reports that oseltamivir (Tamiflu®) and zanamivir (Relenza®) are relatively safe drugs for use in pregnant and breast-feeding women. view more (2009-06-16)
Genetic tests advertised directly to the consumer Genetic testing services have recently begun to be advertised directly to the patient, and the results of the consumers' response can affect public health, as well as the future adoption of pharmacogenetic/genomic testing. view more (2009-07-22)
Live recordings of cell communication A new advanced method for nano-scale imaging of vesicle-fusion - vesicles are biological nano-sized containers - could add to our understanding of diseases of the nervous system and viral infections. view more (2009-08-06)
Researchers explore new ways to prevent spinal cord damage using a vitamin B3 precursor Substances naturally produced by the human body may one day help prevent paralysis following a spinal cord injury, according to researchers at Weill Cornell Medical College. A recent $2.5 million grant from the New York State Spinal Cord Injury Research Board will fund their research investigating this possibility. view more (2009-11-06)
BUSM researchers show dieters can experience neurobiological similarities of drug addicts Researchers from Boston University School of Medicine (BUSM) have shown that intermittent access to foods rich in fat and sugar induces changes in the brain which are comparable to those observed in drug dependence. view more (2009-11-10)
Pitt, US Army team designs new strategy to find drugs to treat neglected infection Using an unconventional approach that they designed, University of Pittsburgh drug discoverers and their collaborators at Walter Reed Army Institute of Research have identified compounds that hold promise for treating leishmaniasis, a parasitic infection that many consider one of the world's most overlooked diseases. view more (2009-11-03)
Heartburn drugs deemed safe for fetuses according to Ben-Gurion University researchers H2 Blocker drugs, such as Famotidine, Cimetidine and Ranitidine, approved in the U.S. for acid reflux (heartburn), pose no significant risks for the fetus according to a large collaborative cohort study by researchers at Ben-Gurion University of the Negev. view more (2009-10-08)
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