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Safer Method for Large-Scale Malaria Screening Developed
Researchers at the Johns Hopkins Bloomberg School of Public Health's Malaria Research Institute have developed a new test for detecting the malaria parasite in human urine and saliva. view more (2006-11-21)
Molecule crucial for processing non-coding RNA identified
The discovery in 1977 that the coding regions of a gene could appear in separate segments along the DNA won the 1993 Nobel Prize in Physiology or Medicine for Richard J. Roberts and Phillip A. Sharp. view more (2005-10-21)
Novel mechanism for DNA replication discovered
Since the discovery of the structure of DNA by James Watson and Francis Crick in 1953, the paradigm for DNA replication has stated that the DNA itself codes for the appropriate pairings for replication. view more (2005-09-30)
Common Enzyme is a Key Player in DNA Repair
A quarter century after they discovered it, researchers have identified the job of one of the most common DNA-damage response proteins. view more (2006-01-12)
DNA size a crucial factor in genetic mutations, study finds
Researchers at Stanford University have created a larger-than-normal DNA molecule that is copied almost as efficiently as natural DNA. view more (2005-10-27)
Genome circularization and RNA virus replication
As featured on the cover of the August 15th issue of G&D, an Argentinian research team, led by Dr. Andrea Gamarnik, report on their recent discovery of a novel mechanism of dengue virus replication. view more (2006-08-01)
Study first to show potential of light-activated gene therapy for knee injuries
An early study has demonstrated for the first time that laser light can target gene therapy right up to the edge of damaged cartilage, while leaving nearby healthy tissue untouched. view more (2006-04-25)
Basic work on E. coli identifies two new keys to regulation of bacterial gene expression
The cellular process of transcription, in which the enzyme RNA polymerase constructs chains of RNA from information contained in DNA, depends upon previously underappreciated sections of both the DNA promoter region and RNA polymerase, according to work done with the bacterium E. coli. view more (2006-06-19)
Little known DNA repair enzyme may be a tumor suppressor gene
The DNA in our cells is constantly being bombarded by environmental, chemical and cellular insults. Fortunately, our cells contain many enzymes devoted strictly to detecting and repairing any damage caused by these insults. view more (2006-01-04)
Core needle biopsy gives an accurate picture of gene expression in whole tumor
The gene expression profile detected in the core needle biopsy of a breast tumour is representative of gene expression in the whole tumour. view more (2006-08-21)
University of Iowa scientists explore function of 'junk DNA'
University of Iowa scientists have made a discovery that broadens understanding of a rapidly developing area of biology known as functional genomics and sheds more light on the mysterious, so-called "junk DNA" that makes up the majority of the human genome. view more (2006-11-14)
How purple corn and RNA break genetic laws
A newly cloned gene in corn will help explain how unusual interactions between a parent's genes can have lasting effects in future generations. The finding has implications for breeding better crop plants and unraveling complex genetic diseases. view more (2006-07-20)
Weizmann Institute scientists discover a molecular security mechanism for keeping mutations in check
Everyone knows mutations - genetic mistakes in DNA, the material of heredity - are bad: The more mutations in the cell's DNA, the higher the risk of cancer developing. view more (2006-05-05)
Towards a unified model of transcription termination
Dr. David Bentley (University of Colorado School of Medicine) and colleagues have developed a new, unified model for transcription termination by RNA Poymerase II. view more (2006-04-07)
Bird flu leaves the nest -- adapting to a new host
Current research suggests that viral polymerase may provide a new therapeutic target for host-adapted avian influenza. view more (2009-08-27)
Novel experiment documents evolution of genome in near-real time
A team led by bioengineering researchers at UC San Diego report in the November issue of Nature Genetics rapid evolutionary changes in a bacterial genome, observed in near-real time over a few days. view more (2006-11-06)
RNA enzyme structure offers a glimpse into the origins of life
Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or "ribozyme," that carries out a fundamental reaction required to make new RNA molecules. view more (2007-03-16)
Schizophrenia and bipolar disorder could have similar genetic causes (pp 758, 798)
Issue 6 September 2003 Embargoed 0001 h (London time) 5 September 2003. Authors of a study in this week's issue of THE LANCET provide strong evidence that schizophrenia and bipolar disorder have a similar genetic cause arising from reduced expression of genes responsible for myelin development of the central nervous system. Schizophrenia and... view more... (2003-09-03)
From a lowly yeast, researchers divine a clue to human disease
Working with a common form of brewer's yeast, University of Wisconsin-Madison researchers have uncovered novel functions of a key protein that allow it to act as a master regulatory switch - a control that determines gene activity and that, when malfunctioning in humans, may contribute to serious neurological disorders. view more (2006-12-08)
Advances in HBV DNA assays are key to determine best long-term treatment strategies for Hepatitis B
For the 350 million people chronically infected with HBV, the two therapeutic approaches currently available are immunomodulatory agents and antiviral chemotherapy. The first therapeutic agent was interferon-alpha (IFN-alpha), whose dual mode of action includes both antiviral and immunomodulatory effects. Unfortunately, extended IFN-alpha... view more... (2005-01-10)
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