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SLU Researchers Uncover Direct Evidence on How HIV Invades Healthy Cells
Using sophisticated detection methods, researchers at the Saint Louis University Institute for Molecular Virology (IMV) have demonstrated the molecular mechanism by which the HIV virus infects, or integrates, healthy cells. The discovery could lead to new drug treatments for HIV. view more (2005-12-22)
Metal-containing compounds show promise as HIV weapon
A molecule consisting of two "cages" of metallic atoms bound to carbon has shown great promise in preliminary tests of becoming a new weapon in the anti-HIV arsenal, researchers at UT Southwestern Medical Center report. view more (2005-11-01)
Enzyme shreds Alzheimer's protein
An enzyme found naturally in the brain snips apart the protein that forms the sludge called amyloid plaque that is one of the hallmarks of Alzheimer's disease (AD), researchers have found. view more (2006-09-21)
Leeches provide source for cardiovascular drugs
The leech has recently confirmed its biomedical interest for scientists by showing that it contains an extensive list of new potential molecules that may become useful tools in the treatment of cardiovascular diseases. view more (2005-10-26)
Cancer cell communication exposed
The discovery, by scientists at Monash University and the Sloan Kettering Cancer Centre in New York, of how communication between cancer cells is controlled has promised new treatment options for malignant tumours. view more (2005-10-31)
Flower power may bring ray of sunshine to cancer sufferers
A mini-protein found in sunflower seeds could be the key to stopping tumors spreading in prostate cancer patients, according to QUT researchers. view more (2008-05-01)
Viral 'fitness' explains different resistance patterns to aids drugs
Some HIV medications lead to the development of drug-resistant HIV when patients take as few as two percent of their medications. view more (2006-01-11)
Study details hepatitis C ability to block immune system response
Hepatitis C virus (HCV) is a worldwide public health problem. The World Health Organization estimates that 170 million people worldwide are chronically infected and that between 3-4 million are newly infected annually. view more (2006-05-19)
Standing up to paraplegia with gene therapy
Elena Rugarli and colleagues from the National Neurological Institute in Milan have used gene therapy to save sensory and skeletal muscle nerve fibers from degeneration in mice with hereditary spastic paraplegia (HSP). view more (2005-12-16)
Gene-specific Ebola therapies protect non-human primates from lethal disease
Scientists have developed a successful strategy for interfering with Ebola virus infection that protected 75 percent of nonhuman primates exposed to the lethal disease. view more (2006-01-13)
How flesh-eating bacteria attack the body's immune system
"Flesh-eating" or "Strep" bacteria are able to survive and spread in the body by degrading a key immune defense molecule, according to researchers at the University of California, San Diego, School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences. view more (2008-08-14)
'Smart' nanoprobes light up disease
Researchers from Rice University's Center for Biological and Environmental Nanotechnology (CBEN) have developed a "smart" beacon hundreds of times smaller than a human cell that is programmed to light up only when activated by specific proteases. view more (2005-08-02)
Casting a wide net to fight coronaviruses
Coronaviruses-the family of viruses that causes the common cold-gained widespread recognition when the deadly severe acute respiratory syndrome, familiarly known as SARS, killed at least 800 people in 2003. view more (2005-09-06)
Newly discovered small molecules
According to the study, these activators bind to specific sites on the neurotoxin protein, increasing protease activity and enhancing the toxin's effect. view more (2006-03-15)
The smoking gun: Elastin fragments drive emphysema
Pulmonary emphysema is caused primarily by cigarette smoking, and the underlying cellular mechanisms are thought to involve smoke-induced activation of tissue degrading enzymes known as proteases. view more (2006-02-10)
Enzyme inhibitors block replication Of SARS virus
Researchers have known since 2003 that a site on the virus is responsible for mediating proteases that allow the virus to replicate. Since then researchers have been testing protease inhibitors to lock up this site, known as SARS 3CLpro, and effectively stop the virus from infecting additional cells in the body. view more (2006-03-28)
Toxic shock: immune system's anthrax link
Human immune proteins crucial for fighting cancer, viruses and bacterial infections belong to an ancient and lethal toxin family previously only found in bacteria, Australian researchers have found. view more (2007-08-24)
Compound has potential for new class of AIDS drugs
Researchers have developed what they believe is the first new mechanism in nearly 20 years for inhibiting a common target used to treat all HIV patients, which could eventually lead to a new class of AIDS drugs. view more (2008-05-15)
Ethnic differences in response to HIV medicines
Researchers from the University of Massachusetts and the University of Pennsylvania have shown that race/ethnicity is a predictor of plasma lipids in patients with HIV-1 on HAART (highly active antiretroviral therapy). view more (2006-01-24)
Researchers probe enzyme that may lead to new SARS drugs
Researchers at the University of Illinois at Chicago and two other institutions have unraveled the structure of an important new drug target from the virus that causes SARS, severe acute respiratory syndrome. view more (2006-04-05)
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