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Progress in understanding the malarial parasite
About 2 million people die of malaria every year, of which more than a million are children in sub-Saharan Africa. Malaria is caused by a protozoan parasite belonging to the genus Plasmodium, and Plasmodium falciparum is responsible for the most severe form of malaria. view more (2007-09-14)
Mosquitoes vs. Malaria: How we can win the fight
EMBL scientists have identified four mosquito proteins that affect the ability of the malaria parasite (Plasmodium) to survive and develop in the malaria-carrier mosquito (Anopheles). This breakthrough, featured in recent issues of Cell (March 5, 2004) and Science (March 26, 2004), could be used to block the transmission of malaria from mosquitoes... view more... (2004-03-22)
Identified mechanism in the malaria parasite to help it adapt to infected individuals
Plasmodium falciparum is responsible for the most severe forms of human malaria. Invasion of host red blood cells is an essential step of the complex life cycle of this parasite. view more (2007-08-03)
Beyond genes: Lipid helps cell wall protein fold into proper shape
A protein that provides a vital passage through a bacterium's outer cell wall will misfold and malfunction if that wall is built of the 'wrong' material, scientists at The University of Texas Medical School at Houston report in a finding that has long-term implications for understanding diseases caused by misfolded proteins such as cystic... view more... (2005-07-18)
Malaria, potato famine pathogen share surprising trait
Two wildly different pathogens — one that infects vegetables, the other infecting humans—essentially use the same protein code to get their disease-causing proteins into the cells of their respective hosts. view more (2006-05-30)
Yale researchers make cell biology quantitative
Yale researchers have reported a method to count the absolute number of individual protein molecules inside a living cell, and to measure accurately where they are located, two basic hurdles for studying biology quantitatively. view more (2005-10-20)
Limpets reveal possible fate of cold-blooded Antarctic animals
A limpet no bigger than a coin could reveal the possible fate of cold-blooded Antarctic marine animals according to new research published this week in The Journal of Experimental Biology. view more (2007-07-24)
Physics and biology team up to tackle protein folding debate
A team of researchers from EPFL, (Ecole Polytechnique Fédérale de Lausanne), the University of Lausanne, Northwestern University and Tel Aviv University bring biology and statistical physics together to answer the question of how molecular chaperones fold, unfold and pull proteins around in the cell. view more (2006-04-04)
Hydrogen bonds shown to play 'conserved' role in protein folding
By changing individual atoms in key places in proteins, Duke University chemists have found new evidence for the importance of comparatively weak "hydrogen bonds" in enabling stringlike proteins to fold into the maximally stable shape they need to assume their roles as biological workhorses. view more (2006-02-13)
Bleeding gums linked to heart disease
Bad teeth, bleeding gums and poor dental hygiene can end up causing heart disease, scientists heard today (Thursday 11 September 2008) at the Society for General Microbiology's Autumn meeting being held this week at Trinity College, Dublin. view more (2008-09-11)
Comparing Chimp, Human DNA
Most of the big differences between human and chimpanzee DNA lie in regions that do not code for genes, according to a new study. view more (2006-10-16)
Scientists make first step towards 'holy grail' of crystallography
Scientists from Imperial College London and the University of Surrey have developed a new technique for crystallising proteins, a discovery which could help speed up the development of new medicines and treatments. view more (2006-01-09)
Bacteria have their own immune system protecting against outside DNA
Bacteria like Salmonella have a complicated immune system that helps them recognize and isolate foreign DNA trying to invade their cell membrane. view more (2006-06-09)
Study finds protein is required for human chromosome production
Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified an elusive protein that performs a necessary step in the production of human chromosomes. view more (2005-10-13)
Sugar helps control cell division
Johns Hopkins scientists have discovered that a deceptively simple sugar is in fact a critical regulator of cells' natural life cycle. view more (2005-09-22)
Researchers discover mechanism that may enable stem cell-based treatment for eye disorders
In discovering a protein that helps organize the development of the retina, UC Irvine researchers have found a new molecular mechanism that may allow for stem cell-based therapies to treat eye disorders such as retinal degeneration. view more (2005-06-24)
Oxygen deprived brains repaired and saved
Scientists from Melbourne's Howard Florey Institute have found special proteins that protect the brain after it has been damaged by a lack of oxygen, which occurs in conditions such as stroke, perinatal asphyxia, near-drowning and traumatic brain injury. view more (2006-08-25)
Free-energy theory borne out in large-scale protein folding
In unprecedented new research, scientists at Rice University have combined theory and experiment for the first time to both predict theoretically and verify experimentally the protein-folding dynamics of a large, complex protein. view more (2005-10-04)
Scientists model 900 cell receptors, drug targets
In an important step toward accelerating drug discovery, researchers have created computer models of more than 900 cell receptors from a class of proteins known to be important drug targets. view more (2006-02-17)
Chronic Alcohol Exposure Can Affect Brain Protein Expression
Researchers at the University at Buffalo studying the effects of alcohol on the brain, using zebrafish as a model, have identified several novel central nervous system proteins that are affected by chronic alcohol exposure. view more (2006-08-30)
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