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Study finds protein is required for human chromosome production
Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified an elusive protein that performs a necessary step in the production of human chromosomes. view more (2005-10-13)
Basic work on E. coli identifies two new keys to regulation of bacterial gene expression
The cellular process of transcription, in which the enzyme RNA polymerase constructs chains of RNA from information contained in DNA, depends upon previously underappreciated sections of both the DNA promoter region and RNA polymerase, according to work done with the bacterium E. coli. view more (2006-06-19)
Scientists unlock more secrets of HIV and SARS
UK scientists have cracked one of the key biological processes used by viruses such as HIV and SARS when they replicate. view more (2006-05-11)
Zooming in on the protein-conducting channel
Researchers have gained the most detailed view yet of the heart of the translocon, a channel through which newly constructed proteins are inserted into the cell membrane. view more (2005-11-17)
New and sharper X-rays of cell's ribosome could lead to better antibiotics
A new, sharper picture of the nano-machine that translates our genetic program into proteins promises to help researchers explain how some types of antibiotics work and could lead to the design of better ones. view more (2005-11-04)
Life's origins were easier than was thought
In the primordial soup that produced life on earth, there were organic molecules that combined to produce the first nucleic acid chains, which were the first elements able to self-replicate. view more (2005-09-16)
Researchers solve mystery of how nuclear pores duplicate before cell division
Researchers have long wondered how nuclear pores - the all-important channels that control the flow of information in and out of a cell's nucleus - double in number to prepare for the split to come when a cell divides. view more (2006-04-21)
Translational derepression & oncogene expression in breast cancer cells
Drs. Anuradha Mehta, Christopher Trotta and Stuart Peltz (PTC Therapeutics) have uncovered a novel mechanism whereby the translation efficiency of oncogenes is increased in cancer cells. view more (2006-03-31)
Fox Chase study sheds light on cancer susceptibility and disease involving bone-marrow failure
Defective protein production can occur in cells even when the genes controlling those proteins are normal. view more (2006-05-12)
Biologists probe the machinery of cellular protein factories
Proteins of all sizes and shapes do most of the work in living cells, and the DNA sequences in genes spell out the instructions for making those proteins. view more (2006-09-14)
Study shows more genes are controlled by biological clocks
The tick-tock of your biological clock may have just gotten a little louder. Researchers at the University of Georgia report that the number of genes under control of in living things than suspected only a few years ago. view more (2008-08-29)
Textbook explanation of mRNA translation may need rethinking
Our understanding of how messenger RNAs are translated into proteins is challenged by new research published today in the Open Access journal Journal of Biology. view more (2005-06-27)
RiboTargets joins Partnership for Structural Biology at the European Synchrotron Radiation Facility
RiboTargets, the structure-based drug discovery company that develops novel cancer and anti-bacterial therapeutics, announced today that it has joined the new Partnership for Structural Biology (PSB) established at the European Synchrotron Radiation Facility (ESRF). Associate membership of the PSB will provide guaranteed access to beamlines at... view more... (2003-01-24)
UCLA researchers outline the structure of the largest non-virus particle ever crystallized
Researchers at UCLA, the California NanoSystems Institute, the David Geffen School of Medicine, and the Howard Hughes Medical Institute have modeled the structure of the largest cellular structure ever crystallized, suggesting ways to engineer the particles for drug delivery. view more (2007-11-27)
Researchers discover how antibiotic inhibits bacterial growth
Researchers at the University of Illinois at Chicago, in collaboration with research teams from Pharmacia & Upjohn and Pfizer, have discovered precisely how the antibiotic linezolid inhibits bacterial growth. view more (2007-05-11)
To sleep, perchance to dream: New insight into melatonin production
In the April 1 issue of G&D, a Korean research team led by Dr. Kyong-Tai Kim (Pohang University) describes how melatonin production is coordinated with the body's natural sleep/wake cycles. view more (2007-04-02)
UIC scientists discover how some bacteria survive antibiotics
Researchers at the University of Illinois at Chicago have discovered how some bacteria can survive antibiotic treatment by turning on resistance mechanisms when exposed to the drugs. The findings, published in the April 24 issue of the journal Molecular Cell, could lead to more effective antibiotics to treat a variety of infections. view more (2008-05-01)
Researchers outline structure of largest nonvirus particle ever crystallized
Researchers at UCLA's California NanoSystems Institute, the David Geffen School of Medicine at UCLA and the Howard Hughes Medical Institute have modeled the structure of the largest cellular particle ever crystallized, suggesting ways to engineer the particles for drug delivery. view more (2007-11-27)
First demonstration of muscle restoration in an animal model of Duchenne muscular dystrophy
Using a new type of drug that targets a specific genetic defect, researchers at the University of Pennsylvania School of Medicine, along with colleagues at PTC Therapeutics Inc. and the University of Massachusetts Medical School, have for the first time demonstrated restoration of muscle function in a mouse model of Duchenne's muscular dystrophy... view more... (2007-04-23)
New insights into how the oncogenic protein c-Myc regulates cell growth
New findings by Swedish and German scientists on the regulation of cellular growth are published in the March issue of Nature Cell Biology. view more (2005-02-20)
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