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Slowing the racing heart
Researchers at the University of Illinois at Chicago explain in the May 11 issue of Circulation Research how an enzyme acts on the heart's pacemaker to slow the rapid beating of the heart's "fight-or-flight" reaction to adrenaline.   view more (2007-05-14)

A new link between stem cells and tumors
Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Institute of Biomedical Research of the Parc Cient√≠fic de Barcelona (IRB-PCB) have now added key evidence to claims that some types of cancer originate with defects in stem cells.   view more (2005-09-06)

Researchers find stem-cell therapy effective in targeting metastatic cancer
Patients with advanced cancer that has spread to many different sites often do not have many treatment options, since they would be unable to tolerate the doses of treatment they would need to kill the tumors.   view more (2006-12-21)

Origen publishes in Nature a robust and versatile method for creating transgenic chickens
Origen Therapeutics announced today that it has succeeded in developing a robust and versatile technology for genetically modifying chickens that, for the first time, puts avian transgenics on a par with transgenic mice.   view more (2006-06-08)

SLU scientists have identified the first gene regulating programmed cell death in plant embryos
A research team at the Swedish University of Agricultural Sciences, SLU, has succeeded in isolating a novel gene that regulates cell death in plant embryos. This is a world first. The team consists of scientists from the Department of Plant Biology and Forest Genetics, headed by Peter Bozhkov and... view more (2004-06-01)

Cells from amniotic fluid used to tissue-engineer a new trachea
Researchers at Children's Hospital Boston report using tissue engineering to reconstruct defective tracheas (windpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then implanting these living grafts into the lambs while still in the womb.   view more (2005-10-10)

Study establishes safety of spinal cord stem cell transplantation
Transplanting human embryonic stem cells does not cause harm and can be used as a therapeutic strategy for the treatment of acute spinal cord injury.   view more (2006-07-20)

Natural protein stops deadly human brain cancer in mice
Scientists from Johns Hopkins and from the University of Milan have effectively proven that they can inhibit lethal human brain cancers in mice using a protein that selectively induces positive changes in the activity of cells that behave like cancer stem cells.   view more (2006-12-08)

Researchers Discover New Factor in Nerve Regeneration
Researchers in Oxford University's Department of Human Anatomy have identified a factor involved in the regeneration of neurons in the central nervous system. The discovery and use of this factor could provide the basis for a reparative treatment for both brain and spinal cord injuries. Unlike... view more (2003-04-07)

Common bacteria pirate natural mechanism to get inside cells
Bacteria and viruses utilize a natural mechanism to get inside cells and grow, researchers say.   view more (2006-01-26)

How embryonic stem cells maintain their identity
Two studies in the April 21, 2006 Cell report new details of the "genetic program" that affords embryonic stem cells the flexibility to give rise to any cell type in the body.   view more (2006-04-21)

FSU biologists uncover mechanisms that shape cells for better or worse
In a landmark study, biologists at Florida State University have uncovered a specific genetic and molecular mechanism that causes cell polarity - the asymmetric shape or composition critical to a cell's proper functioning.   view more (2006-08-17)

Exploring the molecular origin of blood clot flexibility
How do blood clots maintain that precise balance of stiffness for wound healing and flexibility to go with the flow? Researchers at the University of Pennsylvania School of Medicine and the School of Arts and Sciences have shown that a well-known protein structure acts as a molecular spring,... view more (2007-01-15)

A new jump start for aging blood vessels
Recent studies show promise for significantly reducing vascular aging by inactivating TNFa, which has been linked to blood vessel dysfunction and cell death. The related report by Csiszar et al., "Vasculoprotective effects of anti-TNFa treatment in aging," appears in the January issue of... view more (2006-12-28)

Free radical cell death switch identified
Humans and other organisms depend on oxygen to produce the energy required for cells to carry out their normal functions. A cell's engine, the mitochondria, converts oxygen into energy. But this process also leaves a kind of exhaust product known as free radicals.   view more (2006-06-02)

Researchers discover key to human embryonic stem-cell potential
What exactly makes a stem cell a stem cell? The question may seem simplistic, but while we know a great deal of what stem cells can do, we don't yet understand the molecular processes that afford them such unique attributes.   view more (2005-09-09)

Researchers use embryonic model to reprogram malignant melanoma
Scientists at Northwestern University and the Stowers Institute for Medical Research have reprogrammed malignant melanoma cells to become normal melanocytes, or pigment cells, a development that may hold promise in treating of one of the deadliest forms of cancer.   view more (2006-02-28)

U of MN research shows how infection-fighting cells interact
Researchers at the University of Minnesota have identified key insights into how different types of infection-fighting T-cells survive and co-exist within the body's immune system.   view more (2006-03-06)

Researchers make 'embryonic-like' stem cells from umbilical cord blood
A breakthrough in human stem cell research, producing embryonic-like cells from umbilical cord blood may substantially speed up the development of treatments for life-threatening illnesses, injuries and disabilities.   view more (2005-08-18)

Run amok enzyme causes same problems in both humans and fruit flies
An enzyme found at elevated levels in several human cancers has been linked to abnormal tumor growth in fruit flies, a discovery that provides a new model for understanding the link between stem cell biology and cancer, according to researchers at the University of Oregon.   view more (2006-12-19)

Brittlestar provides new model for stem cell research
The brittlestar, Amphiura filiformis, is a close relative of the starfish and can regenerate lost arms in a matter of weeks.   view more (2006-04-10)

New telomere discovery could help explain why cancer cells never stop dividing
A group working at the Swiss Institute for Experimental Cancer Research (ISREC) in collaboration with the University of Pavia has discovered that telomeres, the repeated DNA-protein complexes at the end of chromosomes that progressively shorten every time a cell divides, also contain RNA.   view more (2007-10-05)

Novel connection found between biological clock and cancer
Dartmouth Medical School geneticists have discovered that DNA damage resets the cellular circadian clock, suggesting links among circadian timing, the cycle of cell division, and the propensity for cancer.   view more (2006-06-30)

Stanford study of sea squirt provides clue to human immune system
Until now, no one had demonstrated any concrete similarity between the vertebrate and invertebrate immune systems. The ramifications of the finding may shed light not only on the evolution of our immune system, but also on how we might better control some aspects of it, such as our natural killer... view more (2005-11-28)

Minimal cocktail for growing human embryonic stem cells established
Researchers at Yale have established the minimal nutritional requirements for growing and maintaining human embryonic stem cells, a recipe that is critical for clinical application and for developmental studies.   view more (2006-03-28)

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