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Stem cell therapy successfully treats heart attack in animals
Final results of a study conducted at Johns Hopkins show that stem cell therapy can be used effectively to treat heart attacks, or myocardial infarction, in pigs. view more (2005-07-26)
Fatty acids and caveolin-1 are essential in liver regeneration
Liver regulates lipid, carbohydrate and protein metabolism. It also segregates a number of proteins and enzymes, and eliminates toxic substances from the organism. Liver regeneration is a mostly unknown process at a molecular level, although it is essential for the good functioning of the liver, and indispensable in order to carry out some... view more... (2006-09-19)
How embryonic stem cells maintain their identity
Two studies in the April 21, 2006 Cell report new details of the "genetic program" that affords embryonic stem cells the flexibility to give rise to any cell type in the body. view more (2006-04-21)
Stanford study of sea squirt provides clue to human immune system
Until now, no one had demonstrated any concrete similarity between the vertebrate and invertebrate immune systems. The ramifications of the finding may shed light not only on the evolution of our immune system, but also on how we might better control some aspects of it, such as our natural killer cells. view more (2005-11-28)
Brittlestar provides new model for stem cell research
The brittlestar, Amphiura filiformis, is a close relative of the starfish and can regenerate lost arms in a matter of weeks. view more (2006-04-10)
Studies find general mechanism of cellular aging
Three separate studies confirm a gene that suppresses tumor cell growth also plays a key role in aging. view more (2006-09-07)
Stowers scientists clarify role of tumor suppressor gene
Jiwang Zhang, Ph.D., formerly a Senior Research Associate at the Stowers Institute for Medical Research, and Linheng Li, Ph.D., Associate Investigator, are credited as the first and last authors, respectively, on a paper highlighting several previously unknown functions of phosphatase and tensin homolog (PTEN), an important tumor suppressor gene. view more (2006-04-24)
Xie Lab demonstrates the role of microRNA pathway
Ting Xie, Ph.D., Associate Investigator, and Zhigang Jin, Ph.D., Postdoctoral Research Associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary. view more (2007-02-16)
New target for cancer therapy identified
A new target for cancer therapy has been identified by Monash University scientists investigating the cell signalling pathways that turn on a gene involved in cancer development. view more (2006-09-22)
New study identifies key gene in development of connections between brain and spinal cord
A new study, presented at the American College of Neuropsychopharmacology's (ACNP) Annual Meeting, has identified a specific gene that is necessary for the development of connections between the brain and the spinal cord. view more (2005-12-14)
Malignant melanoma cells secrete protein required for embryo formation
A Northwestern University research group has discovered that aggressive melanoma cells secrete Nodal, a protein that is critical to proper embryo formation. view more (2006-07-31)
Cells from amniotic fluid used to tissue-engineer a new trachea
Researchers at Children's Hospital Boston report using tissue engineering to reconstruct defective tracheas (windpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then implanting these living grafts into the lambs while still in the womb. view more (2005-10-10)
Combination therapy with a monocloncal antibody and a vaccine leads to tumor rejection
Effector T cells (Teff cells) are involved in activating and directing other immune cells, while regulatory T cells (Tregs) act to curb the over-aggressive responses of the T cell population. view more (2006-06-16)
Scientists find stem cell switch
Scientists have discovered how plant stem cells in roots detect soil structure and whether it is favourable for growth. view more (2007-07-27)
Neural stem cell gene plays crucial role in eye development
Scientists at the University of North Carolina at Chapel Hill have demonstrated that normal development of the eye requires the right amount of a neural stem cell gene be expressed at the right time and place. view more (2006-05-16)
First gene associated with myeloproliferative diseases
Myelodysplastic / myeloproliferative diseases (MDS/MPD) are blood stem cell disorders characterized by ineffective formation and development of blood cells in the bone marrow, resulting in abnormal development of bone marrow precursor cells and a reduction in the number of blood cells. view more (2005-08-26)
Expression of 'Blimp1' gene leads to the discovery of cells responsible for skin's sebaceous gland
Mice may not get zits, but they do have oily skin. This week, new research on mice from Rockefeller University shows how the cells responsible for oil production develop, and uncovers clues about how stem cells renew and differentiate. view more (2006-08-11)
OHSU study says stem cell 'fusion' occurs in tumors
An Oregon Health & Science University study is adding credence to an increasingly popular theory that fusion is what bonds stem cells with bone marrow cells to regenerate organ tissue. view more (2006-05-10)
With few factors, adult cells take on character of embryonic stem cells
With the introduction of just four factors, researchers have successfully induced differentiated cells taken from mouse embryos or adult mice to behave like embryonic stem cells. The researchers reported their findings in an immediate early publication of the journal Cell. view more (2006-08-11)
UCLA researchers identify how antibody blocks prostate cancer growth in animal models
Researchers at UCLA's Jonsson Cancer Center have uncovered the mechanism by which an antibody blocks the growth of prostate cancer in animal models, a discovery that could pave the way for development of a new molecularly targeted therapy. view more (2005-10-18)
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