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Bones hold the key to blood renewal
Though we think of them as solid and permanent, our bones are actually constantly being rebuilt throughout our lives. A team of scientists at the Weizmann Institute of Science has now revealed how cells that work at remodeling the bones play a direct part in the ongoing renewal of another system — the blood. view more (2006-06-20)
Researchers aim to cut future need for liver transplants
University of Edinburgh scientists have identified primitive liver cells —possibly dormant from the earliest developmental stage of a human being — which have the potential to mature into different cells types and help repair a failing liver. view more (2006-07-07)
DNA repair in mammal embryos is a matter of timing
Investigators at St. Jude Children's Research Hospital have discovered that the cells of the developing nervous system of the mammalian embryo have an exquisite sense of timing when it comes to fixing broken chromosomes: the cells use one type of repair mechanism during the first half of development and another during the second half. view more (2006-06-20)
Clinical study results using Aldagen's product to isolate cord blood stem cells presented at ASH
Aldagen, Inc. today announced the presentation of data from a clinical trial using its ALDESORT® product to isolate stem cells from cord blood. The trial is being conducted by Joanne Kurtzberg, MD, the Duke University physician who pioneered the use of umbilical cord blood as a treatment for fatal childhood cancers and genetic diseases in... view more... (2006-12-12)
Stem cells make bone marrow cancer resistant to treatment
Scientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that cancer stem cells for multiple myeloma share many properties with normal stem cells and have multiple ways of resisting chemotherapy and other treatments. view more (2008-01-14)
Stem Cell Activity Deciphered in the Aging Brain
Neurobiologists have discovered why the aging brain produces progressively fewer new nerve cells in its learning and memory center. The scientists said the finding, made in rodents, refutes current ideas on how long crucial "progenitor" stem cells persist in the aging brain. view more (2006-12-19)
Evolutionary conservation of a mechanism of longevity from worms to mammals
Though the study of aging in the nematode model organism C. elegans has provided much insight into this complex process, it is not yet clear whether genes involved in aging in the worm have a similar role in mammals. view more (2005-10-05)
Making a face: A new and earlier marker of neural crest development
The fate of cells that go on to form the face, skull and nerve centers of the head and neck in vertebrates is determined much earlier in development than previously thought, and is independent of interaction with other forming tissues. view more (2006-07-12)
Research shows promise for using stem cell transplantation to treat patients with severe lupus
About half of patients with severe lupus that was refractory to standard treatment and who underwent autologous stem cell transplantation to improve their immune system have substantial improvement in disease activity after several years. view more (2006-02-01)
UCSB researchers discover that the cell's endosomes use a surprising transportation system
Cells have developed a surprising transportation system for their endosomes, according to research published today in Physical Review Letters, "Dynamics and Spatial Organization of Endosomes in Mammalian Cells." view more (2005-10-06)
Stem cell breakthrough offers diabetes hope
Scientists have discovered a new technique for turning embryonic stem cells into insulin-producing pancreatic tissue in what could prove a significant breakthrough in the quest to find new treatments for diabetes. view more (2008-04-03)
With few factors, adult cells take on character of embryonic stem cells
With the introduction of just four factors, researchers have successfully induced differentiated cells taken from mouse embryos or adult mice to behave like embryonic stem cells. view more (2006-08-25)
Findings advance use of adult stem cells for replacement bone
In a significant advance for regenerative medicine, researchers at Rice University have discovered a new way to culture adult stem cells from bone marrow such that the cells themselves produce a growth matrix that is rich in important biochemical growth factors. view more (2006-02-14)
Study identifies molecule essential for proper localization of blood stem cells
Scientists at the Massachusetts General Hospital (MGH) Center for Regenerative Medicine and the Harvard Stem Cell Institute (HCSI) have defined a molecule that dictates how blood stem cells travel to the bone marrow and establish blood and immune cell production. view more (2006-01-16)
Sunnybrook researchers identify which sets of molecules are required to induce T cells
Researchers at Sunnybrook Health Sciences Centre have made a critical discovery in T cell development bringing immunologists one step closer to enabling the creation of tailored T cell therapy that could one day be used to treat patients with AIDS or other immune system deficiencies. view more (2006-07-26)
Signaling for cartilage
Skeletal progenitor cells differentiate into cartilage cells when one master gene actually suppresses the action of another, said Baylor College of Medicine researchers in a report that appears online in the journal Proceedings of the National Academy of Sciences. view more (2006-11-28)
Researchers discover important tool in understanding differentiation in human embryonic stem cells
Researchers at the University of Minnesota's Stem Cell Institute have described how an existing genetic tool can be used to study how human embryonic stem cells differentiate. The research appears in the November 2007 issue of Experimental Biology and Medicine. view more (2007-10-25)
Technique to arrest urinary incontinence
The University Hospital of Navarra is to carry out clinical trials for urinary incontinence using the intraurethral injection of myoblasts (adult stem cells obtained by means of a biopsy of the patient). view more (2006-10-04)
Cellular antacids give vaccines a boost
Scientists in Italy have found that a drug that blocks acid buildup inside cells revs up the immune response to vaccines. view more (2005-09-12)
New cell type identified in cancer development
Scientists have discovered a new type of cell that appears to play a role in the development of cancer - a highly volatile, precancerous stem cell that can either remain benign or become malignant, depending upon environmental cues. view more (2007-03-14)
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