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PINK1 protects from Parkinson's
Parkinson disease (PD) is a common neurodegenerative disease characterized by the selective loss of midbrain dopaminergic neurons. view more (2007-06-19)
Colon cancer survival linked to number of lymph nodes examined
An analysis of 17 studies from nine countries has found that the more lymph nodes that are removed and examined during surgical treatment of colon cancer, the better the outcome appears to be for patients. view more (2007-03-21)
No benefit to increasing dose intensity of chemotherapy in osteosarcoma, study finds
A dose-intensive regimen of the chemotherapy drugs cisplatin and doxorubicin offered no clinical benefit over standard doses of the chemotherapy drugs in patients with a bone cancer called osteosarcoma, according to results from a randomized trial in the January 17 issue of the Journal of the National Cancer Institute. view more (2007-01-17)
Improved treatment raises medulloblastoma survival rate
A team of investigators led by St. Jude Children's Research Hospital has announced that improvements in the treatment of the childhood brain cancer medulloblastoma have significantly increased the rate of survival of children with this disease. view more (2006-09-08)
Herceptin plus chemotherapy significantly increases disease-free survival in breast cancer
Combining the molecularly targeted therapy Herceptin with chemotherapy in women with early stage breast cancer significantly improves disease-free survival for patients with a specific genetic mutation that results in very aggressive disease. view more (2006-12-18)
Farmed fish with parasites: impact on wild fish stocks
'Fish farming is often proposed as a solution to diminishing stocks of wild fish. Sadly, many parasites are threatening the future of aquaculture' [by depleting fish stocks], write Jo Cable and Phil Harris, of Cardiff and Nottingham Universities, in the August issue of Biologist. A wide range of invertebrates can live on, or in fish before they... view more... (2003-08-01)
Analysis shows combining sorafenib with carboplatin/paclitaxel adds no benefit in lung cancer
A clinical trial evaluating the benefit of adding the drug sorafenib to the combination of carboplatin/paclitaxel chemotherapy for lung cancer patients has been stopped based on results from an interim analysis, after an independent data monitoring committee concluded that the study would not meet its primary endpoint of improved overall survival. view more (2008-04-28)
Mixed results comparing use of manual vs. automated chest compression following cardiac arrest
Two studies comparing the use of manual chest compression vs. an automated chest compression device during resuscitation for out-of-hospital cardiac arrest produce contrasting findings. view more (2006-06-14)
Three new lung tumor subtypes identified in DNA profiling study
A new study has identified three subtypes of non-small-cell lung cancer tumors, a finding that may provide valuable clinical information about patient survival in early- or late-stage disease, how likely the cancer is to spread and whether the tumor will prove resistant to chemotherapy. view more (2006-10-31)
Anaemia Treatment Could Worsen Cancer Prognosis (p1255)
Results of a European study in this week's issue of THE LANCET cast doubt over the value of treating anaemia with erythropoietin (epoetin beta) among patients who have cancer. Results of the study show that anaemic patients fare better in terms of reduced cancer progression and increased survival if their anaemia is not treated around the time of... view more... (2003-10-15)
Study: Chest compressions without mouth-to-mouth better for out-of-hospital cardiac arrest
A study published March 17, 2007 in The Lancet, one of the world's foremost medical journals, finds that the chances of surviving a cardiac arrest outside a hospital setting are almost twice as high if bystanders perform chest-compression-only resuscitation instead of traditional cardiopulmonary resuscitation (CPR) with mouth-to-mouth breathing. view more (2007-03-16)
Genetic differences influence aging rates in the wild
Long-lived, wild animals harbor genetic differences that influence how quickly they begin to show their age, according to the results of a long-term study reported online on December 13th in Current Biology, a Cell Press publication. view more (2007-12-13)
Experience affects new neuron survival in adult brain; study sheds light on learning, memory
Experience in the early development of new neurons in specific brain regions affects their survival and activity in the adult brain, new research shows. How these new neurons store information about these experiences may explain how they can affect learning and memory in adults. view more (2007-03-23)
A simple, noninvasive test measures survival time in adult pulmonary hypertension
Researchers have developed a simple, noninvasive way to measure right ventricular function in the heart to predict survival of adults who suffer from pulmonary hypertension. view more (2006-11-01)
Recent improvements in prostate cancer outcomes may be result of shift in classification
Some of the improvement in prostate cancer survival rates over the past decade may be due to a shift in the classification of prostate tumors rather than to an actual improvement in outcomes. view more (2005-09-07)
Combined Chemotherapy and Radiotherapy for Cervical Cancer Could Increase Survival (p 781)
A systematic review of randomised trials in the past two decades published in this week’s issue of THE LANCET concludes that women given concurrent chemotherapy and radiotherapy for cervical cancer could have an increased survival-rate of 12% compared with patients treated with radiotherapy alone. Cervical cancer is the second most common... view more... (2001-09-05)
Studies throw light on biomarkers which predict the subsets of patients where gefitinib has the greatest benefit
The drug gefitinib (Iressa) was approved by the U.S. Food and Drug Administration (FDA) in May 2003 under the agency's accelerated approval program for the treatment of patients with non-small cell lung cancer (NSCLC) who had failed two or more courses of chemotherapy. view more (2005-11-16)
Survival rates exceed national averages for UCSF heart, liver and lung transplant programs
One-year survival rates for patients receiving heart, liver and lung transplants at UCSF Medical Center exceed national averages at statistically significant levels, according to new data compiled by the Scientific Registry of Transplant Recipients (SRTR). view more (2008-03-03)
Heart transplants benefit only the sickest patients
Heart transplantation improves survival only in patients with the worst heart failure and therefore at the highest risk of death while on the waiting list, according to a study in this week?s BMJ. This questions the current view in the medical community that transplantation improves the chances of survival for all patients who reach an advanced... view more... (2000-09-01)
Multiple myeloma clinical trial closes early
Mayo Clinic Cancer Center announced today that a multiple myeloma clinical trial has shown a significant improvement in survival with lenalidomide plus low-dose dexamethasone therapy compared to lenalidomide plus high-dose dexamethasone. view more (2007-04-05)
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