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Researchers zero in on estrogen's role in breast-cancer cell growth
Why do estrogen-dependent breast-cancer cells grow and spread rapidly? Researchers at the University of Illinois at Urbana-Champaign say it may be because estrogen virtually eliminates levels of a vitally important regulatory protein.   view more (2005-09-12)

Drug developed at UC Davis may prevent breast cancer, treat post-menopausal vaginal atrophy
A tamoxifen-like drug developed by UC Davis and Finnish researchers, now in clinical testing as a treatment for vaginal atrophy, may also help to prevent breast cancer, two preliminary studies suggest.   view more (2005-11-03)

Primrose oil component cuts levels of cancer-causing gene Her-2/neu
Gamma-linolenic acid (GLA), a substance in evening primrose oil and several other plant oils used in herbal medicine, inhibits action of Her-2/neu, a cancer gene that is responsible for almost 30 percent of all breast cancers.   view more (2005-11-02)

Benefit of chemotherapy in breast cancer depends on estrogen-receptor status
When it comes to chemotherapy treatment for women whose breast cancer has spread to their lymph nodes, the estrogen status of their tumors matters.   view more (2006-04-12)

Breast stem cells have features similar to 'basal' tumors
The most aggressive form of breast cancer may originate from breast stem cells that have undergone genetic mishaps.   view more (2006-07-20)

Researchers say estrogen can kill breast cancer cells once fueled by the hormone
Fox Chase Cancer Center researchers say some breast cancer cells once fueled by estrogen can be killed by the same hormone.   view more (2005-12-07)

Newer chemotherapies improve outcomes for some types of breast cancer
An updated analysis of findings from three major consecutive clinical trials of breast cancer treatment conducted over the past twenty years indicates that women who have breast cancer with lymph node involvement and estrogen-receptor negative tumors have a lower rate of recurrence and risk of death with treatment with newer chemotherapies.   view more (2006-04-12)

Annual Report to the Nation Finds Cancer Death Rates Still on the Decline: Progress in Cancer Treatment Varies by Disease
The nation's leading cancer organizations report that Americans' risk of dying from cancer continues to decline and that the rate of new cancers is holding steady.   view more (2005-10-06)

Serendipity versus planning-cancer drugs of the future?
Delegates at the European Breast Cancer Conference (EBCC-5) were given two examples of promising new drugs to watch in the future-raloxifene and lapatinib.   view more (2006-03-27)

Decline in breast cancer deaths explained by use of screening and adjuvant therapies
Early detection through screening mammography and improved adjuvant treatment have contributed almost equally to the substantial decrease in breast cancer death rates over the past 10 to 15 years.   view more (2005-10-27)

Mayo Clinic study finds two genes predict outcome for breast cancer patients
The 2-gene expression profile of HOXB13 and IL17BR in a woman's breast cancer predicts risk of recurrence in node-negative patients treated with tamoxifen.   view more (2006-04-03)

New biomarker predicts effectiveness of breast cancer drugs
University of Cincinnati (UC) researchers have identified a new way to predict when anti-estrogen drug therapies are inappropriate for patients with hormone-dependent breast cancer.   view more (2006-12-08)

Potential dangers of long term tamoxifen use
Tamoxifen prolongs the life of women with breast cancer and may significantly reduce the risk of developing the disease in those with an inherited tendency. But, suggests a leading article in the Journal of Clinical Pathology, long term use may produce other serious abnormalities, including cancer.   view more (1999-02-12)

Gene variation affects tamoxifen's benefit for breast cancer
One of the most commonly prescribed drugs for breast cancer, tamoxifen, may not be as effective for women who inherit a common genetic variation, according to researchers at the University of Michigan and the Mayo Clinic.   view more (2005-12-19)

Aromatase inhibitors: A treatment of choice for advanced breast cancer patients
Aromatase inhibitors improve the survival of advanced breast cancer patients compared to standard hormone therapies like tamoxifen.   view more (2006-09-20)

Hormone drug type makes survival difference in advanced breast cancer
Aromatase inhibitors, a type of hormone therapy used to treat advanced breast cancer in postmenopausal women, result in a small but significant increase in overall survival when compared to other hormone treatments, according to a new systematic review of studies.   view more (2007-01-31)

Study suggests MPA is effective treatment for hot flashes
Mayo Clinic researchers working with other North Central Cancer Treatment Group (NCCTG) investigators have found that a single dose of depomedroxyprogesterone acetate (MPA) more effectively reduces hot flashes than does the antidepressant venlafaxine (Effexor¬Æ)   view more (2006-03-01)

Chemotherapy and tamoxifen reduce risk of second breast cancer
Among breast cancer patients, both chemotherapy and tamoxifen independently reduced the risk of developing a second cancer in the other breast, according to a study published online December 25 in the Journal of the National Cancer Institute. The risk reduction persisted for at least 10 and 5 years, respectively.   view more (2007-12-26)

Researchers Discover Method in Mice to Restore Tamoxifen Sensitivity in Resistant Breast Cancer
The widely used breast cancer drug tamoxifen (Nolvadex®), which can become less effective over time, might retain its full strength indefinitely if used along with a second drug, according to new research in mice conducted by investigators from the National Cancer Institute (NCI), part of the National Institutes of Health, and their partners.   view more (2006-12-21)

Genetic Engineering & Biotechnology News reports on growing role of molecular diagnostics
Novel platform technologies and key advances in genomics are rapidly driving the development of molecular diagnostics, reports Genetic Engineering and Biotechnology News (GEN).   view more (2008-10-06)
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