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Could vitamin D, a key milk nutrient, affect how you age?
There is a new reason for the 76 million baby boomers to grab a glass of milk. Vitamin D, a key nutrient in milk, could have aging benefits linked to reduced inflammation, according to a new study published in the American Journal of Clinical Nutrition. view more (2007-11-09)
Tiny roundworm's telomeres help scientists to tease apart different types of aging
The continual and inevitable shortening of telomeres, the protective "caps" at the end of all 46 human chromosomes, has been linked to aging and physical decline. view more (2005-08-08)
New telomere discovery could help explain why cancer cells never stop dividing
A group working at the Swiss Institute for Experimental Cancer Research (ISREC) in collaboration with the University of Pavia has discovered that telomeres, the repeated DNA-protein complexes at the end of chromosomes that progressively shorten every time a cell divides, also contain RNA. view more (2007-10-05)
Oncologists could gain therapeutic advantage by targeting telomere protein
Inactivating a protein called mammalian Rad9 could make cancer cells easier to kill with ionizing radiation, according to research at Washington University School of Medicine in St. Louis. view more (2006-02-17)
A little telomerase isn't enough
Chromosome ends, or telomeres, are repetitive stretches of DNA that protect chromosomes in much the same way as plastic tips on shoelaces prevent the fabric from fraying. view more (2005-12-23)
RNAi and telomere length
A team of Russian scientists, led by Dr. Vladimir Gvozdev (Russian Academy of Sciences) reports on a novel link between RNAi and telomere maintenance in the Drosophila germline. view more (2006-02-01)
Evidence of rapid evolution is found at the tips of chromosomes
In terms of their telomeres, mice are more complicated than humans. That's the finding from a recent Rockefeller University study, which shows that mice have two proteins working together to do the job of a single protein in human cells. view more (2006-08-02)
Osteoarthritis may be sign of faster 'biological ageing'
Osteoarthritis, the degenerative inflammatory bone disease, may be a sign of faster "biological ageing," suggests research published ahead of print in the Annals of the Rheumatic Diseases. view more (2006-10-02)
Normal chromosome ends elicit a limited DNA damage response
Researchers at the Salk Institute for Biological Studies discovered that cells co-opted the machinery that usually repairs broken strands of DNA to protect the integrity of chromosomes. view more (2005-11-28)
Scientists Uncover Rules for Gene Amplification
Gene amplification plays an important role in causing cancers via activation of oncogenes. view more (2006-06-30)
UCSF study shows suppression of telomerase enzyme can inhibit spread of melanoma
UCSF researchers have found that the spread of melanoma can be inhibited by suppressing telomerase, the enzyme active in cancer cell growth. view more (2006-07-11)
FISH-ing for links between cancer and aging
Wielding a palette of chromosome paints, scientists at the Salk Institute for Biological Studies have taken a step closer to understanding the relationship between aging and cancer by visualizing chromosomes of cells from patients with a heritable premature aging disease known as Werner Syndrome. view more (2007-02-06)
Shortening chromosomes cause for earlier cancer onset in families with rare syndrome
In families with a high incidence of Li-Fraumeni syndrome, the ends of individuals' chromosomes act somewhat like a lit fuse, according to researchers at The Hospital for Sick Children in Toronto. view more (2007-02-16)
Mayo Clinic study points to a possible biomarker for colon cancer in people 50 and under
An abnormality of chromosomes long associated with diseases of aging has, for the first time, been linked to colon cancer in people 50 years old and younger, an age group usually considered young for this disease. view more (2007-10-29)
Researchers use chemical from medicinal plants to fight HIV
Like other kinds of cells, immune cells lose the ability to divide as they age because a part of their chromosomes known as a telomere becomes progressively shorter with cell division. As a result, the cell changes in many ways, and its disease fighting ability is compromised. view more (2008-11-10)
Gene mutations linked to hereditary lung disease
Scientists at Johns Hopkins have identified the genetic culprits that trigger a hereditary form of a fatal lung disease. The findings, published in the March 29, 2007 issue of the New England Journal of Medicine, may provide new directions in diagnosis and treatment for families that inherit genes for the disease, as well as for those that develop... view more... (2007-03-29)
Hotspots found for chromosome gene swapping
Crossovers and double-strand DNA breaks do not occur randomly on yeast chromosomes during meiosis, but are greatly influenced by the proximity of the chromosome's telomere, according to research in the laboratory of Whitehead Fellow Andreas Hochwagen. view more (2007-11-30)
When cells go bad
When a cell's chromosomes lose their ends, the cell usually kills itself to stem the genetic damage. But University of Utah biologists discovered how those cells can evade suicide and start down the path to cancer. view more (2008-10-01)
Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
New research from scientists at UT Southwestern Medical Center and the Dallas Veterans Affairs Medical Center underscores the importance of preventing recurring acid reflux while also uncovering tantalizing clues on how typical acid reflux can turn potentially cancerous. view more (2007-08-10)
New genetic biomarkers could predict coronary heart disease
New genetic markers may be able to predict whether a person is likely to have coronary heart disease (CAD) in the future. Research carried out by Dr. M. Balasubramanyam and Dr.V.Mohan at the Madras Diabetes Research Foundation (India) shows that people who are pre-diabetic or who have Type 2 diabetes have much shorter telomeres1 and, since these... view more... (2007-04-02)
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