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Tiny roundworm's telomeres help scientists to tease apart different types of aging The continual and inevitable shortening of telomeres, the protective "caps" at the end of all 46 human chromosomes, has been linked to aging and physical decline. view more (2005-08-08)
New telomere discovery could help explain why cancer cells never stop dividing A group working at the Swiss Institute for Experimental Cancer Research (ISREC) in collaboration with the University of Pavia has discovered that telomeres, the repeated DNA-protein complexes at the end of chromosomes that progressively shorten every time a cell divides, also contain RNA. view more (2007-10-05)
Oncologists could gain therapeutic advantage by targeting telomere protein Inactivating a protein called mammalian Rad9 could make cancer cells easier to kill with ionizing radiation, according to research at Washington University School of Medicine in St. Louis. view more (2006-02-17)
Human clones could be ticking time bombs, warns ethics expert Lausanne, Switzerland: Cloning of adults or children for reproductive reasons should be ruled out completely until researchers have discovered ways of counter-acting the health risks associated with the procedure, an expert on the ethics of cloning said today (Wednesday 4 July). Dr Guido de Wert, a senior research fellow in Biomedical Ethics from... view more... (2001-07-04)
DNA repair teams' motto: 'To protect and serve' When you dial 911 you expect rescuers to pull up at your front door, unload and get busy-not park the truck down the street and eat donuts. view more (2006-11-17)
New clues to how sex evolves Sex is a boon to evolution; it allows genetic material from parents to recombine, giving rise to a unique new genome. But how did sex itself evolve\\\ view more (2006-12-05)
A little telomerase isn't enough Chromosome ends, or telomeres, are repetitive stretches of DNA that protect chromosomes in much the same way as plastic tips on shoelaces prevent the fabric from fraying. view more (2005-12-23)
Blame Our Evolutionary Risk of Cancer on Our Body Mass A key enzyme that cuts short our cellular lifespan in an effort to thwart cancer has now been linked to body mass. view more (2006-12-06)
RNAi and telomere length A team of Russian scientists, led by Dr. Vladimir Gvozdev (Russian Academy of Sciences) reports on a novel link between RNAi and telomere maintenance in the Drosophila germline. view more (2006-02-01)
New target for cancer therapy identified A new target for cancer therapy has been identified by Monash University scientists investigating the cell signalling pathways that turn on a gene involved in cancer development. view more (2006-09-22)
Evidence of rapid evolution is found at the tips of chromosomes In terms of their telomeres, mice are more complicated than humans. That's the finding from a recent Rockefeller University study, which shows that mice have two proteins working together to do the job of a single protein in human cells. view more (2006-08-02)
Osteoarthritis may be sign of faster 'biological ageing' Osteoarthritis, the degenerative inflammatory bone disease, may be a sign of faster "biological ageing," suggests research published ahead of print in the Annals of the Rheumatic Diseases. view more (2006-10-02)
Normal chromosome ends elicit a limited DNA damage response Researchers at the Salk Institute for Biological Studies discovered that cells co-opted the machinery that usually repairs broken strands of DNA to protect the integrity of chromosomes. view more (2005-11-28)
Wear and tear of stress: the psychoneurobiology of aging Age may be more related to reactions to stress and the absence of disease rather than to a person's chronological age, say leading researchers in the fields of neurobiology and psychoneuroendocrinology. view more (2006-08-14)
UCSF study shows suppression of telomerase enzyme can inhibit spread of melanoma UCSF researchers have found that the spread of melanoma can be inhibited by suppressing telomerase, the enzyme active in cancer cell growth. view more (2006-07-11)
Short chromosomes put cancer cells in forced rest A Johns Hopkins team has stopped in its tracks a form of blood cancer in mice by engineering and inactivating an enzyme, telomerase, thereby shortening the ends of chromosomes, called telomeres. view more (2007-04-26)
FISH-ing for links between cancer and aging Wielding a palette of chromosome paints, scientists at the Salk Institute for Biological Studies have taken a step closer to understanding the relationship between aging and cancer by visualizing chromosomes of cells from patients with a heritable premature aging disease known as Werner Syndrome. view more (2007-02-06)
Shortening chromosomes cause for earlier cancer onset in families with rare syndrome In families with a high incidence of Li-Fraumeni syndrome, the ends of individuals' chromosomes act somewhat like a lit fuse, according to researchers at The Hospital for Sick Children in Toronto. view more (2007-02-16)
Mayo Clinic study points to a possible biomarker for colon cancer in people 50 and under An abnormality of chromosomes long associated with diseases of aging has, for the first time, been linked to colon cancer in people 50 years old and younger, an age group usually considered young for this disease. view more (2007-10-29)
Researchers use chemical from medicinal plants to fight HIV Like other kinds of cells, immune cells lose the ability to divide as they age because a part of their chromosomes known as a telomere becomes progressively shorter with cell division. As a result, the cell changes in many ways, and its disease fighting ability is compromised. view more (2008-11-10)
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