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Old mystery solved, revealing origin of regulatory T cells that 'police' and protect the body More than 150 years after the discovery of Hassall's corpuscles in 1849, the function of these round blobs of cells in the human thymus gland has now been explained. The answer, in turn, ends an intense hunt for the origin of regulatory T cells that has been under way for years. view more (2005-10-13)
UCLA researchers develop T-cells from human embryonic stem cells Researchers from the UCLA AIDS Institute and the Institute for Stem Cell Biology and Medicine have demonstrated for the first time that human embryonic stem cells can be genetically manipulated and coaxed to develop into mature T-cells, raising hopes for a gene therapy to combat AIDS. view more (2006-07-05)
Mayo Clinic boosts immune system Mayo Clinic researchers have discovered a way to dramatically boost the output of immune system cells from the thymus, which may lead to improved cancer vaccines, as well as to ways to otherwise strengthen immune responses. view more (2005-09-23)
Hopkins study reveals white blood cells can both hurt and help transplanted kidneys In an example of biological irony, the same white blood cell chemistry known to damage kidneys used for transplants may also help prevent such damage, according to a federally funded study in genetically engineered mice at Johns Hopkins. view more (2006-09-21)
'Nurse cells' make life and death decisions for infection-fighting cells "Nurse cells" play an important role in deciding which developing infection-fighting cells, called T cells, live and which die, according to research funded by the National Science Foundation (NSF) and reported in the June issue of the journal Experimental Biology and Medicine. view more (2007-05-31)
Aggressive stem cells might improve transplant outcome Investigators at St. Jude Children's Research Hospital have demonstrated in mice a way that might reduce the time it takes for a bone marrow transplant to rebuild a child's immune system, and so reduce the risk of potentially fatal virus infections that can occur during this time. view more (2006-12-08)
SLU researchers show how to stop muscle weakness caused by myasthenia gravis Severe muscle weakness caused by myasthenia gravis - a highly debilitating autoimmune disorder - can be prevented or reversed by blocking a key step in the immune response that brings on the disease, researchers at the Saint Louis University School of Medicine have found. view more (2007-12-21)
Study shows rituximab effective in treating chronic graft-versus-host disease A study by Dana-Farber Cancer Institute researchers offers the strongest evidence yet of the effectiveness of a novel therapy for chronic graft-versus-host disease (GVHD), a potentially life-threatening complication of donor bone marrow and stem cell transplants. view more (2006-03-27)
Infant transplant patients resist infections that kill adult AIDS patients Investigators have discovered that some type of protective system goes into action in some cases when a baby's immune system is deficient. view more (2006-01-31)
New pathways for autoimmune treatment identified A rare genetic defect that can trigger a host of diseases from type 1 diabetes to alopecia has helped explain the imbalance of immune regulator and killer cells in autoimmune disease. view more (2006-05-30)
A molecular map for aging in mice Researchers at the National Institute of Aging and Stanford University have used gene arrays to identify genes whose activity changes with age in 16 different mouse tissues. view more (2007-11-29)
Researchers train the immune system to deliver virus that destroys cancer in lab models An international team of researchers led by Mayo Clinic have designed a technique that uses the body's own cells and a virus to destroy cancer cells that spread from primary tumors to other parts of the body through the lymphatic system. view more (2007-12-19)
UF researchers track genetic journey of HIV from birth to death University of Florida scientists have discovered how HIV evolves over the course of a person's lifetime into a more deadly form that heralds the onset of full-blown AIDS. The findings could pave the way for new therapeutic agents that target the virus earlier in the disease process, before it takes a lethal turn, researchers say. view more (2007-10-17)
Study identifies key player in the body's immune response to chronic stress Osteopontin (OPN), a protein molecule involved in many different cellular processes, plays a significant role in immune deficiency and organ atrophy following chronic physiological stress, resulting in increased susceptibility to illness. view more (2007-09-04)
Fireflies and jellyfish help illuminate quest for cause of infertility Genes taken from fireflies and jellyfish are literally shedding light on possible causes of infertility and autoimmune diseases in humans. view more (2009-03-27)
T cell immunity enhanced by timing of interleukin-7 therapy That the cell nurturing growth factor interleukin-7 can help ramp up the ability of the immune system to remember the pathogenic villains it encounters is well known. view more (2008-02-04)
New study shows that important gene controls the ability of the thymus to produce disease-fighting T-cells after an organism's birth New research, just published by researchers from the University of Georgia, provides the first evidence that a key gene may be crucial to maintaining the production of the thymus and its disease-fighting T-cells after an animal's birth. view more (2008-11-07)
Mice stressed in simulated weightlessness show organ atrophy A ground-based, experimental model used to simulate astronaut weightlessness in space has provided Rutgers scientists an opportunity to study the effects of stress on immune organs. view more (2007-09-04)
Embryonic stem cells might help reduce transplantation rejection Researchers have shown that immune-defense cells influenced by embryonic stem cell-derived cells can help prevent the rejection of hearts transplanted into mice, all without the use of immunosuppressive drugs. view more (2008-09-16)
Genetic study shows direct link between vitamin D and MS susceptibility 'gene' Researchers have found evidence that a direct interaction between vitamin D and a common genetic variant alters the risk of developing multiple sclerosis (MS). view more (2009-02-05)
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