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Study sheds light on signaling mechanism in stem cells, cancer
UCSF scientists have illuminated a key step in a signaling pathway that helps orchestrate embryonic development.   view more (2005-10-26)

The hormone of darkness: melatonin could hurt memory formation at night
What do you do when a naturally occurring hormone in your body turns against you? What do you do when that same hormone - melatonin - is a popular supplement you take to help you sleep? A University of Houston professor and his team of researchers may have some answers.   view more (2007-11-16)

Chronic Alcohol Exposure Can Affect Brain Protein Expression
Researchers at the University at Buffalo studying the effects of alcohol on the brain, using zebrafish as a model, have identified several novel central nervous system proteins that are affected by chronic alcohol exposure.   view more (2006-08-30)

Junk DNA may not be so junky after all
Researchers at the McKusick-Nathans Institute of Genetic Medicine at Johns Hopkins have invented a cost-effective and highly efficient way of analyzing what many have termed "junk" DNA and identified regions critical for controlling gene function.   view more (2006-03-24)

How does a zebrafish grow a new tail?
If a zebrafish loses a chunk of its tail fin, it'll grow back within a week. Like lizards, newts, and frogs, a zebrafish can replace surprisingly complex body parts. A tail fin, for example, has many different types of cells and is a very intricate structure. It is the fish version of an arm or leg.   view more (2006-12-27)

Key to zebrafish heart regeneration uncovered
When a portion of a zebrafish's heart is removed, the dynamic interplay between a mass of stem cells that forms in the wound and the protective cell layer that covers the wound spurs the regeneration of functional new heart tissue.   view more (2006-11-03)

Lipids play important role in nervous system development
Blocking a signaling lipid can keep nerves from developing the arm-like extensions they need to wire the body and may even cause neurons to die, researchers have found.   view more (2005-10-25)

Oregon researchers show how resident bacteria shape gut development
University of Oregon researchers have shown that bacteria residing in the intestine shape gut development by means of several distinct signaling mechanisms.   view more (2006-06-22)

Study shows how the zebrafish gets his stripe
Scientists have discovered how the zebrafish (Danio rerio) develops one of its four stripes of pigment cells.   view more (2007-09-26)

A new way to treat colon cancer?
Researchers at University of Utah's Huntsman Cancer Institute have discovered a new target for possible future colon cancer treatments - a molecule that is implicated in 85 percent of colon cancer cases.   view more (2006-10-10)

Jefferson researchers find nanoparticle shows promise in reducing radiation side effects
Using transparent zebrafish embryos, researchers at Jefferson Medical College have shown that a microscopic nanoparticle can help fend off damage to normal tissue from radiation.   view more (2005-11-15)

Jefferson Scientists Uncover Lethal Gene Mutation Key to Blocking Cholesterol Processing
When Jefferson Medical College researcher Shiu-Ying Ho, Ph.D., and her colleagues first created a mutation that limited the absorption of lipids and cholesterol into the bloodstream in zebrafish, the possibilities seemed endless.   view more (2006-04-20)

Study fishes out new role for prostaglandins
Prostaglandins - the fat-derived compounds linked to pain, inflammation, reproduction and cancer - can add another biological function to their extensive catalog.   view more (2006-01-03)

Malignant melanoma cells secrete protein required for embryo formation
A Northwestern University research group has discovered that aggressive melanoma cells secrete Nodal, a protein that is critical to proper embryo formation.   view more (2006-07-31)

Mutant gene causes severe kidney disease in infants
Scientists at the University of Michigan Medical School have discovered a previously unknown cause for a severe, early-onset form of kidney disease and renal failure in children: recessive mutations in a gene called phospholipase C epsilon or PLCE1.   view more (2006-11-06)

In early embryos, cilia get the message across
Having your heart in the right place usually means having it located on the left side of your body. But just how a perfectly symmetrical embryo settles on what's right and what's left has fascinated developmental biologists for a long time.   view more (2006-10-23)

A fisheye view of the deadliest breast cancer
Inflammatory breast cancer (IBC) is the deadliest form of the disease, with fewer than half of those diagnosed today having a five-year prognosis for survival.   view more (2006-12-13)

Reversing cancer cells to normal cells
In earlier work, Northwestern University scientist Mary J.C. Hendrix and colleagues discovered that aggressive melanoma cells (but not normal skin cells nor less aggressive melanoma cells) contain specific proteins similar to those found in embryonic stem cells.   view more (2007-04-30)

Starting over: Wnt reactivates dormant limb regeneration program
Chop off a salamander's leg and a brand new one will sprout in no time. But most animals have lost the ability to replace missing limbs. Now, a research team at the Salk Institute for Biological Studies has been able to regenerate a wing in a chick embryo - a species not known to be able to regrow limbs-suggesting that the potential for such... view more... (2006-11-20)

Fish get insomnia, eyes wide open, say Stanford sleep researchers
Scientists at the Stanford University School of Medicine have hooked a fish that suffers from insomnia in their quest to understand the genetics behind sleep disorders.   view more (2007-10-16)
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