Brightsurf Science News & Current Events

February 02, 1999
Immunex's TRAIL Molecule Shows Potential As Anti-Tumor Agent
A preclinical study published in the journal Nature Medicine today demonstrated that TRAIL (TNF-related apoptosis-inducing ligand) supresses tumor growth, and in some instances caused complete remission of tumors, by a direct and specific mechanism.

Growth Factors Improve Muscle Healing In Animals
Several growth factors speed the healing of muscle injuries in animal models, paving the way for these compounds to be used one day in people with similar injuries, according to a University of Pittsburgh presentation at the Orthopaedic Research Society meeting in Anaheim, Calif.

Scientists Use Bioengineering To Buy Time For Ailing Hearts
Researchers at Toronto's Hospital for Sick Children have successfully used bioengineering to prevent the closing of a key passage between the two large vessels leading out of the heart.

Growth Factor Contributes To Angiogenesis
A University of Michigan team has found that a natural substance known as vascular endothelial growth factor (VEGF) contributes to angiogenesis not only by stimulating blood vessel growth, but also by prolonging the survival of blood vessel cells.

Growing Younger By Keeping Up Regular Physical Activity
Walking, weightlifting, flexibility training and other exercises can help seniors avoid disabilities and even reverse the aging process itself.

Gene Knockout Prolongs Ovarian Lifespan In Mice
A research team based at the Massachusetts General Hospital has found that inactivation of a single gene in female mice can sustain ovarian function into advanced age.

University Of Pittsburgh Develops Sensitive, Accurate Probe To Measure Cartilage Damage
Investigators at the University of Pittsburgh have developed a probe that can accurately measure the extent of damage to articular cartilage, according to a report being presented on Feb.

Wood-Based Composites Center Established At Virginia Tech
Recognizing that composites are the future of the wood products industry, Virginia Tech researchers in the College of Forestry and Wildlife Resources have established with industry partners a Wood-Based Composites (WBC) Center.

How Nerve Cells Get In Touch - A Molecular Model Of Synapse Formation And Retrograde Signalling In The Brain
Researchers at the Max Planck Institute for Experimental Medicine, Göttingen/Germany, and at the University of Texas Southwestern Medical Center, Dallas/Texas, characterized a novel family of cell surface proteins that may regulate the generation of functional networks between nerve cells in the brain by inducing synapse formation (Proc.

At-Home Or In-Class, Wellness Lessons Aid Chronically Ill
A home-based wellness program that combines videotaped instruction in relaxation, exercise, and nutrition is just as effective in helping older adults cope with chronic illnesses as providing the program in a classroom setting.

Small G-Proteins Make A Big Difference -- Nerve Cell Signalling Is Regulated By Arf-GTPases And Their Activators
Researchers at the Max Planck Institutes for Biophysical Chemistry and for Experimental Medicine in Göttingen/Germany discovered a new regulatory process through which nerve cells modulate the release of neurotransmitter in the brain (Proc.

Researchers Determine Three Dimensional Structure Of Melatonin Producing Enzyme
Researchers from two NIH institutes have determined the three-dimensional structure of an enzyme that produces melatonin--a key hormone that regulates the body's internal clock.
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