Brightsurf Science News & Current Events

September 30, 2000
MS clinical trials confirm approach, demonstrate need to carefully refine targeted peptide therapy
Two clinical trials of a targeted peptide therapy in patients with relapsing-remitting multiple sclerosis (MS) have been halted due to adverse effects.

Tailoring mitochondria to the cell's needs
Cells increase their complement of mitochondria in response to rising metabolic demands or altered physiological conditions.

Topical application of a protein heals wounds
NIDCR scientists have discovered that a multipurpose protein (secretory leukocyte protease inhibitor) found in several bodily fluids can promote the healing of abnormal skin wounds, which are a significant problem in the elderly.

Alcohol and bone fragility
In addition to liver disease, alcoholics are at risk of other ailments, including fragile bones.

Free radicals in alcoholic liver disease
The fatty degeneration of the liver characteristically seen in alcoholics has been ascribed to cellular damage mediated by free radicals.

U-M team finds evidence of brain chemistry abnormalities in bipolar disorder
People with bipolar disorder have an average of thirty percent more of an important class of signal-sending brain cells, according to new evidence being published by University of Michigan researchers.The finding solidifies the idea that the disorder has genetic roots, and may explain why it runs in families.

Researchers prevent obesity and diabetes in mice
Researchers have developed genetically-altered mice that do not become obese or develop diabetes when fed a high-fat diet.
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