Brightsurf Science News & Current Events

December 31, 2000
Aspirin use may increase pancreatic cancer risk
The many health benefits of regular aspirin use have been well-documented, and include the prevention of certain cancers, heart attacks and strokes, as well as dementia, Alzheimer's disease and cataracts.

Other highlights in the November 5 issue of JNCI
Other highlights of the November 5 issue of JNCI include two studies indicating that factory workers who are routinely exposed to formaldehyde may have an increased risk of certain cancers.

Other highlights in the October 15 issue of JNCI
Other highlights of the October 15 issue of JNCI include a study examining risk factors for malignant melanoma, a study on racial differences in the treatment of early-stage breast cancer, a study finding a lack of evidence that SV40 is a prevalent human pathogen, and a study showing no increase in the incidence of childhood leukemia in Nordic countries over the last 20 years.

IGF-binding protein-5 as a growth factor in its own right
Miyakoshi et al. tested the effect of insulin growth factor-I (IGF-I) on IGF-binding proteins (IGFBPs) in bone formation, and they conclude that IGFBP-5 is itself a growth factor.

Converging pathways regulate energy metabolism
Harris et al. argue that two distinct leptin-dependent signaling pathways activate the TRH promoter in the paraventricular nucleus of the hypothalamus (PVH).

NIH scientists highlight role of macrophages in HIV infection
NIAID scientists report that macrophages, specialized immune system cells, contain and continue to produce large amounts of an HIV-like virus in monkeys even after the virus depletes CD4+ T cells, the primary HIV target in infected individuals.

Estrogen has antitumor activity in hormone therapy-resistant breast tumors
A pair of studies in the November 5 issue of the Journal of the National Cancer Institute suggest that low levels of estrogen--the same hormone that promotes breast cancer in its early stages--can shrink breast tumors that have developed resistance to the drugs tamoxifen and raloxifene.

In a new observational analysis, Risedronate significantly reduced nonvertebral fracture risk
In a new observational analysis presented at the 25th Annual Meeting of the American Society for Bone and Mineral Research (ASBMR), osteoporosis patients taking risedronate (Actonel®) had a 59 percent (p=0.04) lower risk of nonvertebral fracture than patients receiving alendronate (Fosamax®) and a 75 percent (p<0.01) lower risk than patients receiving nasal calcitonin, at one year of treatment.

Smugglers face neutron test
To crack down on people trying to smuggle nuclear material, US scientists have made a new improved detection system which can even penetrate lead cargo containers.

Early treatment of blinding eye disease in infants can prevent severe vision loss
An important clinical trial, sponsored by the National Eye Institute (NEI), a part of the National Institutes of Health (NIH), has provided doctors with improved prognostic indicators and treatment options for retinopathy of prematurity (ROP), a blinding disease that affects premature, low birthweight infants.

Inactivated flu vaccine linked to fewer medical visits than intranasal vaccine
A study among US military personnel finds that those who received a flu shot with the trivalent inactivated vaccine had fewer subsequent health care visits related to pneumonia and influenza than those who received an intranasal live attenuated influenza vaccine, according to a study appearing in the March 4 issue of JAMA, and being released early online with two other reports on drug-resistant influenza.

Growing Cancer Threat Among Native Americans Receiving Scant Attention, UB Studies Show
While cancer is a leading cause of death among Native Americans, providers of health care to these populations give cancer a low priority and commit few funds to its prevention, two University at Buffalo studies have shown.

Creation of molecular nano motor: Fraser Stoddart/UCLA
Chemists at Italy's University of Bologna, UCLA and the California NanoSystems Institute have created a molecular nano motor that does not consume fuels, and is powered only by sunlight.

Pharmaceutical 'smart bomb' targets cancer cells
Rutgers pharmaceutical chemist Longqin Hu and his colleagues have developed a new series of compounds for drugs that have the potential to attack cancer like a high-tech

Three genetic steps convert normal mammary cells into breast cancer cells
Cells originating from normal human breast tissue have been converted into breast cancer cells by a defined protocol of genetic changes.

Some Americans, fed up with conflicting diet and nutrition messages, respond with less healthful eating habits
As incremental advances in scientific knowledge cause shifts and reversals in diet and health messasges, what are confused, frustrated consumers to do?

New generation of bone building drugs for men
Researchers at the Hebrew University of Jerusalem are developing bone-building preparations to counter osteoporosis in men.

Tower collapse theory changed
A controversial theory about the collapse of the World Trade Center towers will soon be tested.

Enigma or just noise?
For centuries, artists, historians and tourists have been fascinated by Mona Lisa's enigmatic smile.

New imaging research reveals dysfunction in the brain's 'hub' in the earliest stages of schizophrenia
A new brain imaging study from the Institute of Psychiatry shows for the first time that the thalamus, the brain's main sensory filter or 'hub', is smaller than normal from the earliest stages of schizophrenia.

Chemokines and angiostasis
Romagnani et al. report that human microvascular endothelial cells from a variety of normal tissues express the chemokine receptor CXCR3, several of whose ligands are strongly angiostatic.
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