Brightsurf Science News & Current Events

May 17, 2004
Scents will not rouse us from slumber, says new Brown University study
Smells do not wake people, according to Brown University researchers who studied responses to the scents peppermint and pyridine - a common byproduct of fire.

Cutting-edge science offers improved care for liver diseases
The liver is the largest organ in the human body, and proper functioning is critical for health and well being.

Inhibition of cathepsin proteases inhibits tumor formation in transgenic mice
A new research study provides evidence that inhibition of cathepsin cysteine proteases may be a viable strategy for treatment of human cancers.

Investigational drug may provide new option for preventing transplant organ rejection
A unique investigational treatment called LEA29Y may represent a novel, less toxic way to preserve transplanted kidney function and improve patient outcomes, according to new data to be presented at the American Transplant Congress.

Imaging study shows brain maturing
The brain's center of reasoning and problem solving is among the last to mature, a new study graphically reveals.

Financially burdened patients more likely to die after coronary revascularization
Heart patients who had angioplasty or bypass surgery and felt burdened by medical costs were more than twice as likely to die within a year of their procedure as patients who didn't have trouble paying for healthcare.

One step further toward treatment for degenerative diseases
Scientists at McGill have discovered a key step that will provide new targets for treatments of degenerative diseases such as Alzheimer's, Cystic Fibrosis and Diabetes.

Matching method helps doctors successfully transplant higher-risk kidneys
By carefully matching the estimated function of kidneys from deceased donors with the needs of potential recipients, surgeons can successfully transplant kidneys that would otherwise be discarded.

GI health affected by consumption of coffee and carbonated drinks
According to new research presented today at Digestive Disease Week (DDW), drinking caffeinated beverages may benefit some people who are at high-risk for liver disease.

Oxygen therapy may improve vision worsened by diabetes
Oxygen delivered through the nose may improve poor vision caused by diabetic macular edema, fluid buildup in the part of the eye responsible for central vision, according to a pilot study by scientists at Johns Hopkins and the National Eye Institute.

Study: Low-carb diet more effective than low-fat diet
People who followed a low-carbohydrate, high-protein diet lost more weight than people on a low-fat, low-cholesterol, low-calorie diet during a six-month comparison study at Duke University Medical Center.

New insights on sirtuins, involved in gene expression and aging
A family of enzymes called sirtuins is known to play critical roles in a variety of vital life processes, including metabolism, aging, and gene expression.

Speech recognition experts at OGI School of Science & Engineering receive nearly $700,000 in grants
Three new grants received by researchers in the Center for Spoken Language Understanding (
Toll-free road from sepsis
Immune system failure to limit the spread of a bacterial infection results in sepsis: a loss of control on the normal inflammatory response, with a 70% mortality rate.

Scientists track protein linked to movement disorder
A team led by researchers at Washington University School of Medicine in St.

New global trials help to make FOSRENOL(R) the most extensively studied modern phosphate binder
In the wake of its first regulatory approval in Sweden, Shire's new non-calcium, non-aluminium phosphate binder FOSRENOLĀ® (lanthanum carbonate) is set to undergo further assessment in twin phase IIIb studies in the US and Europe / Canada (with over 450 patients in each).

CellCept(R) registry data demonstrated superior long-term organ transplant outcomes
Data presented today at a top U.S. transplant meeting demonstrated better patient and graft (organ) survival in liver and kidney transplant patients taking CellCeptĀ® (mycophenolate mofetil) compared to those receiving treatment regimens not including CellCept.

Kidney cancer surgery safer at high-volume hospitals
In the first study to look nationwide at the relationship between surgical volume and mortality for nephrectomy for cancer, researchers at the University of Michigan Health System found patients faced a 32 percent lower risk of dying at high-volume hospitals compared to hospitals that performed fewer nephrectomies.

Cedars-Sinai Medical tipsheet for May 2004
The May medical tipsheet from Cedars-Sinai Medical Center includes tips about women's health screenings, CVS and prenatal diagnosis, stem cell/brain tumor research, high-tech hip replacement, novel approaches addressing the nursing shortage, seasonal allergies, the bioartificial liver and more.

Clinical trial shows drug may offer a new option to prevent rejection of transplanted kidneys
Results of a preliminary study suggest that a treatment called LEA29Y works as well as the standard therapy, cyclosporine, to prevent acute kidney transplant rejection, with less potential for long-term harm to the organ and the patient, and better functioning of the transplanted kidney.

Florida frontier expedition
With new state funding, scientists from Harbor Branch Oceanographic and Florida Atlantic University will be exploring never before seen sections of the seafloor off Florida.

Diabetics at significantly higher risk for Alzheimer's disease
Diabetes mellitus is linked to a 65 percent increased risk of developing Alzheimer's disease (AD) and affects some aspects of cognitive function differently than others, according to a new study conducted by Alzheimer's disease researchers from Rush University Medical Center.

ADAM: Good enzyme for Alzheimer disease
Alzheimer Disease (AD) is a neurological disorder characterized by amyloid beta-peptides (AB peptides) forming plaques in the brain.

Government psoriasis research funding down over last decade while NIH budget up 148%
Over the last decade, as NIH funding increased by 148%, psoriasis research funding at NIH's National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) actually decreased by 13%.

National Academies news: The Engineer of 2020
To enhance the nation's economic productivity and improve the quality of life worldwide, engineering education in the United States must anticipate and adapt to the dramatic changes of engineering practice expected in the coming decades, says a new report from the National Academies' National Academy of Engineering.

Diabetes linked to increased risk of Alzheimer's in long-term study
Diabetes mellitus was linked to a 65 percent increased risk of developing Alzheimer's disease (AD), appearing to affect some aspects of cognitive function differently than others in a new study supported by the National Institute on Aging (NIA) at the National Institutes of Health.

Chatty washer cleans up access to high-tech appliances
A smooth-talking washing machine may not be savvy enough to keep a user from mixing whites and darks, but it can open doors that the digital revolution has closed to the blind.

Body fat and its role in breast cancer
Among factors that influence breast cancer risk, body fat has been shown to play a role, but studies on fat distribution are uncertain.

Chemical company earnings jump in 2004 first quarter
Chemical company earnings soared and production and prices increased in the first quarter of 2004, compared to the same time last year, reports Chemical & Engineering News in its in the May 17 issue.

On the edge: Are we at risk of an ESRD pandemic?
Data presented at this year's ERA-EDTA1 congress in Lisbon supports predictions by renal experts that rates of kidney disease in Europe are set to soar, largely as a result of the growing worldwide incidence of diabetes.

Anti-clotting treatment underused at many hospitals
Academic hospitals are more likely than community or Veteran's Administration (VA) hospitals to follow national guidelines for treating patients at risk for blood clots with aspirin or warfarin.

Land Regeneration Network celebrates first year success
The first year's successes enjoyed by a unique all-Wales Land Regeneration Network, led by Cardiff University, have been welcomed by Welsh Assembly Ministers.

Diabetes drug improves metabolic changes associated with HIV combination therapy
Use of an oral antidiabetes medication produced significant improvement in a group of patients with HIV lipodsytrophy, a syndrome involving the redistribution of fat and other metabolic changes in those receiving combination drug therapy for HIV infection.

NPS Pharma and VIMAC Ventures locate at MaRS, a major new research and enterprise center in Toronto
Salt Lake City-based NPS Pharmaceuticals and Boston-based VIMAC Ventures announced today that they plan to locate key business and research facilities to the new MaRS (Medical and Related Sciences) Discovery District biosciences research and commercialization hub in downtown Toronto.

Regional review boards improve liver transplant allocation
A new study shows that regional review boards fairly and accurately distinguish between high and low risk patients.

Studies indicate healthy eating may affect cancer development, improve digestive system
Making simple dietetic changes, such as incorporating green tea and fruits, may have a large impact on gastrointestinal health, according to new research presented today at Digestive Disease Week in New Orleans.

Hamster hamburger anyone?
Transmissible spongiform encephalopathies (TSEs) are fatal neurological disorders caused by accumulation of a misfolded form of the prion protein (PrPSc) in the central nervous system.

Advances emerging in hepatitis management
Hepatitis, a potentially serious disease caused by a virus that attacks the liver, is a major problem worldwide.

Stuart Lipton honored with Jung Prize for Medicine
Stuart A. Lipton, M.D., Ph.D., Professor and Director of the Del E.

Protein marker predicts possible heart damage after chemotherapy
High levels of troponin I (TNI) protein in the blood helps identify possible heart damage after cancer treatment.

Two studies weigh in on low-carb diets
Two randomized trials reported in the May 18, 2004, issue of Annals of Internal Medicine compared low-carbohydrate diets with low-fat diets.

Mouse study yields clue to why liver is less prone to rejection, say Pitt researchers
Researchers from the University of Pittsburgh believe they have identified a mechanism that helps explain why the liver enjoys privileged immunological status over other organs, making it the least vulnerable to rejection when transplanted.

Annals of Internal Medicine, tip sheet, May 18, 2004
In the May 18 edition of the Annals of Internal Medicine, titles include two studies find positives in low-carb diets, task force does not recommend for or against screening for suicide risk, and four views of restricting medical residents' work hours.

When 'reaper' gene comes, cell death follows
In what may be the cellular equivalent of watching the Grim Reaper in action, University of Utah School of Medicine researchers have shown that two

New insight into how tumors resist radiation
Scientists have uncovered new evidence about a critical cellular pathway that makes tumor blood vessels resistant to radiation therapy.
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