Brightsurf Science News & Current Events

December 05, 2004
Long-term benefits for newly diagnosed patients with CML receiving first-line therapy with imatinib
CHU in Poitiers, France, today announced results of a study showing that newly diagnosed patients with a certain form of leukemia who are treated early with imatinib are more likely to achieve complete cytogenetic responses (the elimination of leukemic cells, a major goal of therapy) and have improved long-term outcomes.

Ongoing transfusions needed to avoid strokes in children with sickle cell disease
The 10 percent of children with sickle cell disease who are at risk for a stroke need ongoing blood transfusions to reduce their risk, according to a study at 25 sites in North America.

NHLBI stops sickle cell anemia transfusion study
The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) has stopped early a clinical trial studying whether children with sickle cell anemia at high risk for stroke could at some point after a minimum of 30 months safely stop receiving the periodic blood transfusions that prevent strokes.

Read your shampoo's label: Study finds common ingredient stunts developing neurons of rats
A biocide found in many shampoos and hand lotions and widely used in industrial settings inhibits the development of neuron structures that are essential for transmitting signals between cells, according to a University of Pittsburgh study presented today Cell Biology 2004.

Study shows haploidentical natural killer cells may provide hope for some patients with AML
A University of Minnesota Cancer Center study indicates natural killer cells obtained from a family member and artificially stimulated may provide renewed hope for some patients who have advanced acute myelogenous leukemia (AML), a highly fatal cancer of the bone marrow, that has become resistant to standard treatment with chemotherapy.

Chimpanzee brains are asymmetrical in key areas and their handedness reflects it
New MRI-based studies present more evidence that the brains of chimpanzees are human-like in terms of the relationships among brain asymmetry, handedness and language, according to research undertaken at the Yerkes National Primate Research Center in Atlanta.

Low platelet counts linked to decreased survival in HIV-infected women
HIV-positive women with low blood platelet counts face significantly higher risk of death compared to women with normal counts, according to a study presented today at the 46th Annual Meeting of the American Society of Hematology.

Yerkes researchers discover baisis for determining handedness in chimpanzees
Contrary to long-accepted scientific thought, researchers have found that handedness is not associated with the language area of the brain.

Novel drugs help solve Gleevec resistance
Two different novel targeted therapies can produce strong responses in patients who have become resistant to Gleevec(tm), the standard therapy for chronic myeloid leukemia (CML), researchers at The University of Texas M.

Prediction of gene function in mammals
Gene function in mammals can be quickly and reliably predicted using a high-throughput analysis of patterns of RNA expression, according to an article published today in Journal of Biology. This challenges the conventional view that tissue-specificity is the best predictor of function, and could speed up the quest to understand whole genomes, in humans and other mammals, by decades.

New drug sidesteps Gleevec resistance in human trials
An experimental drug under development by Bristol-Myers Squibb is showing early promise in reversing the signs and symptoms of patients whose chronic myeloid leukemia failed to respond to Gleevec, which is considered the standard of treatment for the disorder.
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