Brightsurf Science News & Current Events

April 18, 2005
Observational study suggests use of statins lowers risk of advanced prostate cancer
Use of such cholesterol-lowering drugs as statins may reduce the risk of advanced prostate cancer, according to research that followed 34,428 U.S. men for more than a decade.

Research reveals emotional trauma parents face when a child is diagnosed with diabetes
Discovering a child has diabetes can be a traumatic and life-changing event for parents - and researchers doubt whether many of them ever come to terms with it.

Combination of Lipitor® and Celecoxib
Combinations of Lipitor® and Celebrex® (celecoxib) at lower doses proved more effective at limiting colon cancer than higher doses of the drugs when given alone, according to research reported at the 96th Annual Meeting of the American Association for Cancer Research here today.

Oceanographers collect 1.5 million year record of climate change in Africa
Oceanographers have probed the ancient sediments beneath Lake Malawi in East Africa and recovered sediment samples that provide up to 1.5 million years of information about how climate in Africa has changed - the longest continuous record of such data ever collected from that continent.

NSAIDs cut risk of oral cancer among smokers
People who chose to light up cigarettes may want to take nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin or ibuprofen as well, according to research reported here at the 96th Annual Meeting of the American Association for Cancer Research today.

Multiple-drug resistant gene expression pattern predicts treatment outcome for pediatric leukemia
A new study is providing scientists with a better understanding of why some pediatric acute lymphoblastic leukemia (ALL) patients fail to respond to treatment even when existing clinical predictive criteria point towards a positive treatment outcome.

To sea or not to sea: When it comes to salmon sex, size sometimes doesn't matter
The ones that stay and the ones that stray are biological puzzles among Pacific salmon, of whom the vast majority - but not all - travel thousands of miles to sea and back to the streams where they hatched.

Taking the piste out of Alpine vegetation
According to new research published today in the British Ecological Society's Journal of Applied Ecology, machine grading and artificial snow production is causing significant changes in the number and type of plant species in the European Alps.

NSAIDs provoke a specific portfolio
Taking celecoxib, a COX-2 inhibitor better known as Celebrex, has been found to alter a specific

Gene therapy completely corrects hemophilia in laboratory animals
Newborn mice and dogs with hemophilia A were restored to normal health through gene therapy developed by researchers at Washington University School of Medicine in St.

Starting salaries remain 'depressed' for 2004 chemistry grads
When adjusted for inflation, median salaries for 2004 bachelor's, master's and Ph.D. chemistry graduates were about 10 percent below the salaries received by chemists who graduated three or four years earlier, reports Chemical & Engineering News in its April 18 issue.

Scientist works to reduce side effects of radiation therapy
A Wake Forest University Baptist Medical Center researcher has received a $1.5 million grant to study whether the same drugs that fight obesity and diabetes may be able to also prevent a common side effect of cancer treatment - the cognitive problems that can follow whole-brain radiation.

RHIC scientists serve up 'perfect' liquid
Simultaneous peer-reviewed publications by the four detector groups conducting research at the Relativistic Heavy Ion Collider (RHIC) say the giant atom

Melbourne researchers develop safer and more effective 'aspirin'
Monash University and Cerylid Biosciences Ltd have discovered and developed a new class of anti-clotting drugs that appears to be more effective than aspirin at preventing disease-causing blood clots with fewer side effects.

University of Nevada, Reno professor showcases 'mini' ion accelerator
Particle accelerators are a key research tool in a high energy physicist's arsenal, but they take up a lot of space - miles and miles of it.

Children on school buses may face increased exposure to diesel pollution
Diesel particle pollution inside urban school buses may be worse than levels found in the surrounding roadway air, according to a study by scientists at the University of California.

NIAID begins clinical trial of West Nile virus vaccine
A small trial testing the safety of an experimental vaccine targeting West Nile virus (WNV) opened today at the National Institutes of Health's (NIH) Clinical Center in Bethesda, MD.

A trusting boss is a successful boss
'Everyone only does as much as they absolutely have to,' is a key tenet of Economics.

Obesity adds risk of cardiovascular disease in siblings in families with a history of heart problems
A Johns Hopkins study finds that people who have a family history of heart disease have more reason than most to keep their weight down.

Ice-covered Baltic Sea proves ideal setting for final pre-launch CryoSat validation
The northernmost part of the Baltic Sea, between Finland and Sweden, recently provided an ideal location for scientists to successfully address critical issues relating to sea ice validation before CryoSat is launched in September.

NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
In mouse models of intestinal cancer, use of an anti-inflammatory drug eliminated all of the cancer-causing risks produced by a high-fat Western-style diet − even when several genetic brakes to cancer formation were missing in the animals, say researchers from the Albert Einstein Cancer Center.

Water research initiatives at UW-Madison
Reporters looking for fresh environmental research angles for Earth Day (April 22) - or for environmental coverage throughout the year - can find scores of newsworthy projects at UW-Madison related to water resources, from groundwater to the Great Lakes.

Drugs targeted at muscle cells
Now scientists at Karolinska Institutet have established that a type of drug targeted at receptors in the muscle cells increases the metabolism and absorption of glucose, making it a potential tool in the treatment of diabetes.

Tea may help prevent diabetes and cataracts
Add another line to the list of benefits from drinking tea: New research in animals suggests that tea may be a simple, inexpensive means of preventing diabetes and its ensuing complications, including cataracts.

Penn researchers determine structure of binding site of colon-cancer drug and its protein target
Researchers at the University of Pennsylvania School of Medicine have determined the precise molecular details of how Erbitux, a recently approved colorectal cancer drug, binds to its target on cancer cells.

Protective effect of calcium in reducing colon cancer polyps lasts for years
Long term use of calcium supplements provides a protective effect that lasts for years against development of potentially precancerous colon polyps, researchers at Dartmouth Medical School say.

Nitrogen fertilization of soil puts rare plant species at risk, nationwide study determines
Rare plant species are six times more likely than abundant species to be lost due to nitrogen fertilization of soil, UC Irvine biologist Katharine Suding and colleagues have found through experiments conducted across nine ecosystems in North America.

Sex, age and sun exposure linked to frequency of sunburns
In Danish volunteers, sunburn was typically associated with female sex, younger age, high risk behaviors like sunbathing, and long hours exposed to the sun, according to an article in the April issue of Archives of Dermatology, one of the JAMA/Archives journals.

Dermatologists use knowledge of patterns to recognize melanoma
Dermatologists depend on overall pattern recognition and comparison rather than specific analytic criteria to distinguish melanoma lesions (malignant skin cancer) from harmless skin moles, according to an article in the April issue of Archives of Dermatology, one of the JAMA/Archives journals.

New approach to cancer treatment shown to be highly effective
Lpath Therapeutics Inc, has developed a monoclonal antibody against sphingosine-1-phosphate (S1P) and has validated S1P as a therapeutic target for cancer.

Annals of Internal Medicine, tip sheet, April 19, 2005
Highlights include: Vaccination plus antibiotics best strategy after anthrax attack, study finds; Metformin and lifestyle changes slow metabolic syndrome; and Primary care is endangered in US.

Mesotherapy not proven as a safe alternative to liposuction
The allure of shedding unwanted pockets of fat with a series of simple injections, known as mesotherapy, sounds too good to be true - and it just might be.

Sensorial evaluation of the freshness of fish
AZTI has drawn up some 40 tables for freshness specific for the most important commercial species in southern Europe, including fish and shellfish.

Surgery for children with sleep apnea improves quality of life
Children with obstructive sleep apnea (OSA) have improvements in their quality of life as well as their sleep disorder after surgical removal of the tonsils and adenoid tissue, according to an article in the April issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.

Patients' lives at risk from substandard drugs say heart specialists
Global action is needed to counter the dangers of substandard life-saving drugs that are putting patients' lives and health at risk, according to heart specialists writing in the new (19 April) issue of Europe's leading cardiology journal, the European Heart Journal.

Virus-host interactions at sea effect global photosynthesis
In a study published in the freely-available online journal PLoS Biology, an analysis of the genome sequences of three phages capable of infecting marine unicellular cyanobacteria Prochlorococcus reveals they are genetically complex with intriguing adaptations related to their oceanic environment.

Friendly bacteria in humans may protect against HIV
Scientists have identified good bacteria already living in some humans that target and trap HIV and may protect against infection.

Cornell graduate student named 2005 AIBS Emerging Public Policy Leader
The American Institute of Biological Sciences, a Washington-based nonprofit scientific association, has named Cornell University PhD candidate Karen Deen Laughlin as its 2005 Emerging Public Policy Leader.

Elephant seal pups suffer from ocean warming
Ocean warming has a negative impact on the condition of elephant seals, reveals a study published in the Open Access journal BMC Biology.

Five giant impact basins reveal the ancient equator of Mars
A Canadian researcher has calculated the location of Mars' ancient poles, based upon the location of five giant impact basins on the planet's surface.

Fox Chase Cancer Center researchers look for 'silenced' genes to monitor kidney cancer patients
Researchers at Fox Chase Cancer Center in Philadelphia say looking for genes that have been turned off by cancer cells may become a reliable and noninvasive way to detect and monitor cancer in the kidney.

Long term outcomes for children who undergo ear tube placement surgery
Infants and young children who undergo surgery to insert ventilation tubes in their ears as a treatment for ear infections have hearing levels comparable to normal children 14 years later, although children with more serious disease may require repeat procedures or other ear surgery, according to two studies in the April issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.

New research reveals working mothers do not adversely impact on children's diets
A new study from the University of Glasgow that analyses information from 11 year old children and their parents reveals that maternal employment is associated with better diets.The research challenges the streotype of working mothers who regularly dish out ready made meals, to reveal that children of parents who work may be fed more healthily.

Compounds in plastic packaging act as environmental estrogens altering breast genes
Compounds found in plastic products used to wrap or contain food and beverages have aroused concerns as possible cancer-causing agents because they can sometimes leach out of the plastic and migrate into the food.

Surgery season and vitamin D intake may predict successful lung cancer surgery
Successful outcomes for surgery to treat early stage lung cancer appear to depend on the level of vitamin D present in a patient − a calculation that includes food sources, supplements, as well as the season of the year during which the operation is performed, according to researchers at Harvard School of Public Health and Harvard Medical School.

Columbia study shows women benefit from drug-eluting stents as much as men
Doctors generally believe that women do not respond as well to drug eluting stent treatments, but a Columbia University Medical Center study shows that drug eluting stents are just as effective and safe in women as they are in men.

Activating ATR
As published in the May 1 issue of G&D, Dr.

NCI's Patient Navigator Research Program: Questions and answers
NCI is addressing unequal patterns of access to standard care by conducting a NCI-sponsored Patient Navigation Research Program at multiple sites.

Gastric bypass patients fare better as surgical programs' experience increases
Risk of serious complications and death following gastric bypass surgery for morbid obesity may be reduced substantially when the surgery is performed at high volume centers and the surgeons have reached the 100 case experience, according to an article in the April issue of Archives of Surgery, one of the JAMA/Archives journals.

Undesirable expatriates: Preventing the spread of invasive animals
Reconsider relocating aquarium fish into your backyard pond. Restrain yourself from ordering exotic pets off the Internet, no matter how interesting they might look in the pictures.

B-15A collides with Antarctic ice tongue
Maps of Antarctica need to be amended. The long-awaited collision between the vast B-15A iceberg and the landfast Drygalski ice tongue has taken place.

Anthrax treatments' cost effectiveness shown in Stanford study
Study from the Veterans Affairs Palo Alto Health Care System, Stanford University School of Medicine and University of Toronto has found that the timely use of both antibiotics and vaccination is the most cost-effective way to treat people potentially exposed to anthrax.

The Neurosciences and Music in Leipzig: Registration boom and over 140 posters
The second international conference dedicated to the neurosciences and music and their interactions, organized by the Fondazione Mariani Onlus in Leipzig from the 5th to the 8th of May 2005.The conference has been organized primarily in partnership with the Max Planck Institute for Human Cognitive and Brain Sciences of Leipzig and in cooperation with the New York Academy of Sciences.

Georgia Tech research reveals how biomaterial properties control cellular responses
New Georgia Tech research reveals how cells

More evidence suggests statins help cut risk for advanced prostate cancer
In a 10-year study of more than 30,000 health professionals, researchers at Johns Hopkins and Harvard found that the longer men take cholesterol-lowering drugs such as statins, the far less likely they are to develop advanced prostate cancer.

Variant in gene associated with telomeres predicts longer survival of deadly brain tumor
An exceptionally large study of patients with glioblastoma multiforme has found an association between a genetic variation and a doubling of survival rate - the strongest link ever established between genetic variation and outcome in this deadliest form of brain cancer, according to researchers at The University of Texas M.

Study reveals dramatic difference between breast cancers in US and Africa
A study comparing, for the first time, breast cancers from Nigeria, Senegal and North America has found that women of African ancestry are more likely to be diagnosed with a more virulent form of the disease than women of European ancestry.

Child magazine editor addresses region's first annual women's and children's health care conference
Karen Cicero, a senior editor at Child magazine, will be among the keynote speakers this Thursday, April 21st at the first annual women's and children's health care conference,

Hawaiian soils reveal clues to cultural history
The emergence of warriors, priests and rulers in Hawaii before the Europeans arrived in 1778 ultimately depended upon the quality of soil available for cultivation.

First matter
When the first matter came into being right after the big bang, what was it like?

Learning software developed by Rutgers-Newark scientist helps 450,000 students with reading
About 450,000 American schoolchildren all have used educational Fast ForWord software products developed from research that began in the lab of Rutgers-Newark professor of neuroscience Paula Tallal.

Gene expression pattern predicts multiple drug resistance, treatment failure in pediatric leukemia
The discovery of a specific pattern of gene expression linked to multiple-drug resistance of leukemic cells is giving researchers crucial information into why standard therapies fail to cure some children with acute lymphoblastic leukemia (ALL).

Virtual colonoscopy: Virtually promising
In an April 19 Annals of Internal Medicine editorial, Indiana University School of Medicine gastroenterologist Thomas Imperiale, M.D., says virtual colonoscopy may become one of the most valuable assessment tools available for colorectal cancer screening.

American Society of Travel Agents urges healthy travel for consumers
As the 2005 travel season swings into high gear, the American Society of Travel Agents (ASTA) announced today that in a recent survey, 56 percent of U.S. travelers plan their itinerary for their vacation while just 19 percent seek travel health advice from a healthcare professional prior to departure.

Observations of distant galaxies show fundamental constant unchanged in 7 billion years
A fundamental constant of nature, called the fine structure constant, is central to all equations describing light and its interactions with matter.

Duke theorists play role in search for superhot 'quark-gluon plasma'
Duke University theoreticians said their predictions helped guide the efforts of experimenters using Brookhaven National Laboratory's Relativistic Heavy Ion Collider (RHIC) atom smasher to create an almost perfectly flowing fluid of hot, dense matter.

Newborn's first week may be critical period for developing obesity in adulthood
Babies who gain weight rapidly during their very first week of life may be more likely to be overweight as young adults, according to a new study.

PNAS highlights for the week of April 18 - 22
This week's highlights include research on happiness and biological function, Chinese herbal medicine and cancer, and the evolution of altruistic punishment.

Neural activity reveals continuity between infant and adult sleep
Research published in the premier open-access online journal PLoS Biology reveals that unexpectedly, the anatomy and neurophysiology of brainstem areas associated with sleep in the neonatal rat are strikingly similar to the adult.

Putting ecology back into river restoration
An ambitious plan is under way in the ecological community to agree a set of standards for ecologically successful river restoration.

Alternate view for pathology of AD
A paper challenges the classic theory that the nerve tangles seen in the brains of Alzheimer's disease victims are the cause of the disease, but rather proposes that they are a protective response to the disease.

Can money grow on trees? Win-win strategies for 'sustainable bioprospecting'
'Biodiverse' developing countries have yet to cash-in on their 'green gold.' And with more pharmaceutical companies turning to exploring other new technologies as sources for new drugs, it is becoming increasingly clear that poor countries might never realize the full benefits of their genetic endowments.

UNH water treatment researchers win AAEE Grand Prize for Research
A UNH professor was awarded the Grand Prize for Research by the American Association of Environmental Engineers at the National Press Club April 14.

A little stress gives beneficial oomph! to immune system
New research in mice provides more evidence that a brief bout of stress can give the immune system a beneficial boost - under certain conditions.
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