Brightsurf Science News & Current Events

May 14, 2005
Study shows doctors and patients think differently about clinical trials
A survey of patients and physicians regarding clinical trials shows that doctors don't recognize the importance of side effects as a barrier for their patients in deciding about whether to undergo experimental therapy.

Mayo Clinic researchers use pharmacogenetic test prior to chemotherapy to reduce toxic side effects
Mayo Clinic researchers report that using a genetic screening blood test prior to the start of chemotherapy can decrease the toxicity of a three-drug chemotherapy regimen, thus helping patients tolerate markedly different amounts of each of the three drugs.

Eye candy: Transcriptional control of vertebrate eye development
Published in the May 15th issue of G&D, Dr. Greg Lemke and colleagues have determined that two ventral anterior homeobox (Vax) genes act as intracellular effectors of Shh signaling in the developing eye field and are required for proper optic nerve formation.

Drug combination boosts survival rate in head and neck cancers
Adding a third drug to a standard chemotherapy combination can dramatically improve the survival of patients with advanced head and neck cancer, according to a study led by researchers at Dana-Farber.

Location, location, location: Effect of nuclear organization on transcriptional status
Published in the May 15th issue of G&D, Dr. Pamela Silver and colleagues have taken a systems approach to address the correlation between a gene's location in the nucleus and its transcriptional activity.

New kidney cancer drug response rate is more than double that of standard treatment
Recent studies of a new anticancer drug show continued response for patients with late-stage kidney cancer.

Surgery to treat vocal-cord spasms shows high success rate
The first large, long-term study of patients who had surgery to control vocal-cord spasms showed excellent results in the majority of cases, reports new UCLA research presented May 14 at the 126th Annual Meeting of the American Laryngological Association.

Counting cells in blood samples may predict cancer treatment's effectiveness
Counting the amount of a type of normal cell circulating in the blood of people with cancer could predict whether a tumor progresses or responds to therapy, a new study led by the University of Michigan Comprehensive Cancer Center has found.

Study finds Herceptin may have role in bladder cancer treatment
A targeted drug shown to improve the outcome of certain breast cancer patients may be of use in the treatment of advanced cases of bladder cancer, according to new research led by the University of Michigan Comprehensive Cancer Center.
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