Brightsurf Science News & Current Events

December 20, 2005
Investigational boosted protease inhibitor, TMC114, works better with FUZEON
Exciting interim data presented at the annual ICAAC conference show that adding FUZEON (enfuvirtide) to the investigational boosted protease inhibitor (PI), TMC114/r, more than doubles the proportion of patients reaching undetectable levels of the virus.

Also in the December 21 Journal of the National Cancer Institute
Other highlights in the December 21 JNCI include two studies of methodology for investigating biomarkers for cancer, a study that examines the origins of secondary lesions in the female genital tract, and a study examining a receptor associated with poor survival in esophageal cancer.

Getting a handle on minimal surfaces
A twisted soap bubble with a handle? Experts had thought for more than 200 years that such a structure was not even mathematically possible.

Genetic testing still smart choice, despite uncertainties
Preimplantation genetic diagnosis has been used for more than a decade to screen embryos for hereditary diseases such as Down syndrome and other abnormalities.

Depression is not good for your heart
According to a large-scale study in Sweden, people who have been diagnosed with depression, especially younger patients between 25 and 50 years of age, are at increased risk of developing coronary heart disease (CHD) later in life.

Patient outcomes linked to biomarker levels by quantitative technology
Researchers in the Department of Pathology at Yale University School of Medicine report that when using current pathology methods of biomarker detection, the concentration of antibodies used dramatically alters the apparent relationship of biomarker level to clinical outcome.

Health care plans for Medicare beneficiaries are not all alike
If you are a Medicare beneficiary, should it matter whether your health care plan is for-profit or not-for-profit?

Mom and dad are key to how we handle stress
Our relationship with our parents affects how we cope.

Screening chest x-ray detects early-stage lung cancers at high rates, study results show
Almost half of lung cancers detected by a chest x-ray were early-stage cancers, according to baseline results of a large, randomized clinical trial that is testing the efficacy of a chest x-ray as a screening test for lung cancer.

Researchers show how air pollution can cause heart disease
Animal study reveals tiny particles in the air are even more damaging when coupled with a high-fat diet.

Clinical trial to test stem cell approach for children with brain injury
FDA-approved clinical trial will be the first of its kind to evaluate a stem cell therapy for traumatic brain injury.

Poor health of female flight attendants linked to sexual harassment
Female flight attendants who have been sexually harassed by passengers are almost three times as likely to rate their health as only fair or poor, reveals research in the Journal of Occupational and Environmental Medicine.

Tooth loss and heart disease linked, even among nonsmokers
There is a strong, progressive association between tooth loss and heart disease, researchers report in a study published in the latest issue of American Journal of Preventive Medicine.

Ultraviolet B light exposure associated with increased risk of skin cancer
A decreased ability to repair chromosomal damage caused by exposure to ultraviolet B (UV-B) radiation in test tubes may be associated with an increased risk of the common skin cancers basal cell carcinoma and squamous cell carcinoma, but not of melanoma, according to a study in the December 21 issue of the Journal of the National Cancer Institute.

Pall blood filtration technology removes prions that can cause TSEs
A newly published study in the December issue of Transfusion shows a Pall Corporation (NYSE: PLL) filtration technology is effective in removing prions from blood.

DMSO raises a stink at sewage treatment plants
Researchers believe they've found the source of a stinking problem that has plagued areas surrounding sewage treatment plants for decades.

Combating depression in women with nursing interventions
Low-income women at risk of depression can be helped through the use of cognitive-behavioral interventions including affirmation and thought stopping, recent research shows.

Men with erectile dysfunction have increased risk for cardiovascular events
Men with erectile dysfunction have a higher risk of subsequent cardiovascular events such as heart attack, stroke, and angina, according to a study in the December 21 issue of JAMA.

Visualization techniques can help smokers quit
A new study supports previous research done that used guided health imagery to help smokers quit.

Virtual microscopy project wins educational technology award
The annual Educational Technology Award of the University of Helsinki has been granted to the project: Virtual microscopy as a teaching aid.

Poor fitness common in teens and adults, with associated rise in cardiovascular disease risk factors
Approximately one-third of adolescents and 14 percent of adults (aged 20 to 49 years) in the US have poor cardiorespiratory fitness, with an associated increased prevalence of cardiovascular disease risk factors such as higher total cholesterol and blood pressure levels, according to a study in the December 21 issue of JAMA.

New UK guidelines significantly widen criteria for heart disease and stroke prevention
New joint guidelines published by six professional societies today in Heart significantly widen the criteria for prevention of heart disease and stroke in primary care, and are set to boost the numbers of patients targeted for screening and preventive treatment.

Researchers demonstrate single molecule absorption spectroscopy
A powerful new tool for probing molecular structure on surfaces has been developed by researchers at the University of Illinois at Urbana-Champaign.

Researchers provide study of early heart development and underlying cause of congenital heart defects
Researchers at the Burnham Institute for Medical Research have provided detailed insights into the early formation of the heart.

Heart burn medication a risk factor for community-acquired C. difficile
Researchers have discovered that drugs, such as heart burn medications, which reduce gastric acidity, are potential risk factors for Clostridium difficile infection outside of hospitals.

Poor cardiovascular fitness raises heart disease risk in teens, adults
Poor cardiorespiratory fitness affects one of five persons aged 12 to 49 years in the United States, with a disproportionate impact on adolescents, adult females and non-white minorities.

Brain research wins $1 million
One of Australia's leading neuroscience researchers has been awarded $1 million dollars to fund his ongoing cutting-edge Australian research into brain disorders.

Mining biotech's data mother lode
A EU-sponsored project has developed a suite of tools that will enable biotech companies to mine through vast quantities of data created by modern life-science labs to find the nuggets of genetic gold that lie within.

Dover decision is good for long-term economic and scientific strength
The following is a statement from Alan I. Leshner, CEO of the American Association for the Advancement of Science (AAAS) and executive publisher of the journal Science, in response to the decision by the US District Court for the Middle District of Pennsylvania in Kitzmiller, et al. v.

New approach for genetic screening for syndrome linked to cardiac irregularities and sudden death
Italian researchers have developed a novel approach for genetic screening for long QT syndrome (LQTS), an inherited disease that predisposes young individuals to cardiac arrhythmias and sudden death, according to a study in the December 21 issue of JAMA.

New NASA satellites shipped to launch site
NASA 's Space Technology 5 (ST5) micro-satellites have arrived at the Vandenberg Air Force Base, Calif., launch site and are in the beginning stages of final launch preparation.

Adults also suffer from cyclical vomiting syndrome
Migraines and panic attacks may be the triggers for cyclical vomiting syndrome in adults, according a small study published today in the open access journal BMC Medicine.

Celebrity voice-overs: That unfamiliar voice could be selling you something
B-list celebrities whose voices are used in television commercials are more likely to positively influence consumers because they're less recognizable.

MSG-2 will advance long-term monitoring of Earth's energy balance
This week's launch of MSG-2 will ensure that satellite images continue to be available to European weather forecasters well into the next decade.

White women with skin cancer history more likely to develop melanoma
Older white women with a history of non-melanoma skin cancer are at greater risk for developing melanoma, regardless of the amount of sun they have been exposed to, finds a study the online journal Cancer.

File compression can expand mammography's power
Digitized mammograms are actually interpreted more accurately by radiologists once they have been

US citizens hail court ruling
Scientists and nonscientists alike applauded a US district court decision ruling that a school board violated the Constitution by requiring high school science students to learn about

Adults with lazy eye can improve
An abstract exercise delivers concrete results for young subjects with an

Successful treatment for acute heart failure remains elusive
In recent years, cardiologists have begun to view acute heart failure syndrome (AHFS) as a distinct condition.

Melanoma risk only partially associated vith exposure to UVB from sunlight
Researchers at The University of Texas M. D. Anderson Cancer Center have found that the risk of developing melanoma, the most deadly form of skin cancer, is only partially associated with exposure to ultraviolet B (UVB) radiation, the rays in sunlight that increase in summer and cause sunburn.

Arterial leg disease may be more common in blacks
African-Americans are more likely to have problems with circulation in their legs due to hardening of the arteries, or atherosclerosis, according to a national study of more than 15,000 adults.

Transplanted stem cells show promise for mending broken hearts
Working with heart attack-stricken mice, a team of University of Wisconsin-Madison scientists has shown that embryonic stem cells may one day live up to their clinical promise.

Blocking the nerve receptor EP1 in mouse models reduces brain damage caused by stroke
Researchers at Johns Hopkins have discovered how to block a molecular switch that triggers brain damage caused by the lack of oxygen during a stroke.

UCI wins $2.4 million grant to study how brain understands language
A UC Irvine cognitive neuroscientist has been awarded a National Institutes of Health grant for $2.4 million over five years to unlock the secrets of how the brain translates sound waves into meaningful language.
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