Brightsurf Science News & Current Events

January 14, 2006
Tool developed to silence genes in specific tissues using RNAi
Researchers at The University of Texas M. D. Anderson Cancer Center say they have jumped a significant hurdle in the use of RNA interference (RNAi), believed by many to be the ultimate tool to both decode the function of individual genes in the human genome and to treat disease.

WT1, male fertility and tumorigenesis
Dr. Miles Wilkinson and colleagues use a new tissue-specific RNAi approach they developed to identify a novel postnatal role for the Wilms' tumor 1 (WT1) tumor suppressor in spermatogenesis.

Translational control by RINGO/Spy
Dr. Joel Richter's laboratory at UMASS Medical School has identified a critical role for the RINGO/Spy protein in the control of cytoplasmic polyadenylation.
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