Brightsurf Science News & Current Events

January 15, 2007
Researchers from the CIMA have discovered a possible cause of thrombosis
A team of researchers from the CIMA of the University of Navarra has discovered a possible cause of thrombosis, and has developed a new diagnostic test for this disease.

U of MN adult stem cell research shows promise for transplant therapies
University of Minnesota stem cell researchers, together with collaborators at Stanford University, have successfully used adult stem cells to replace the immune system and bone marrow of mice, offering the promise of new therapies for people in the future.

Dual enzymatic activity of RECQ1 explained by different quaternary structures
RecQ helicases can either unwind or anneal strands of DNA.

40,000-year-old skull shows both modern human and Neandertal traits
Humans continued to evolve significantly long after they were established in Europe, and interbred with Neandertals as they settled across the continent, according to new research published this week in the Proceedings of the National Academy of Sciences.

Researchers discover genetic cause for word-finding disease
Northwestern University researchers have discovered a genetic cause of a mysterious neurological disease in which people have trouble recalling and using words.

Lab research may one day lead to cancer treatment using patient's own immune cells
Julian A. Kim, M.D., chief of surgical oncology at University Hospitals Ireland Cancer Center, has received a $660,000 grant from the National Institutes of Health for a five-year study that hopes to lead to new treatments using a set of immune cells, called T cells, to fight skin cancer (melanoma) and breast cancer.

Dual gene therapy suppresses lung cancer in preclinical test
Combination gene therapy delivered in lipid-based nanoparticles drastically reduces the number and size of human non-small cell lung cancer tumors in mice, researchers at The University of Texas M.

Why are lions not as big as elephants?
A simple theoretical model provides a framework to understand carnivore energy budgets and reveals insights into the evolution of body size in mammalian carnivores.

Selective marker found to indicate aggressive form of breast cancer
Researchers have linked a structural protein called nestin to a particularly deadly form of breast cancer, identifying a new biomarker that could lead to earlier detection and better treatment.

One-time melanoma screening of older adults appears to be cost-effective
One-time melanoma screening of adults age 50 or older appears to be as cost-effective as other nationally recommended cancer screening programs, according to an article in the January issue of Archives of Dermatology, one of the JAMA/Archives journals.

Researchers discover surprising drug that blocks malaria
Northwestern University researchers have uncovered how malaria parasites break into red blood cells and how to block the invading parasites with a commonly prescribed high-blood pressure medication.

Queen's discovery provides new hope for people with advanced breast cancer
A surprising discovery by Queen's University researchers that happened when their work took an unexpected turn may help women with advanced breast cancer respond better to conventional drug treatments.

Tip sheet: Annals of Internal Medicine, Jan. 16, 2007, issue
The following articles are featured in the Jan. 16, 2007, issue of Annals of Internal Medicine tip sheet:

ACS News Service Weekly PressPac -- January 10, 2007
The American Chemical Society News Service Weekly Press Package with reports from 35 major peer-reviewed journals on chemistry, health, medicine, energy, environment, food, nanotechnology and other hot topics.

Early life family structure and microbially induced cancer risk and more
In a 28-year study of 261 Japanese-American men who carried Helicobacter pylori belonging to a large family or being born later in the family was associated with a significantly increased risk of developing gastric adenocarcinoma late in life.

Nanotechnology shows promise as next wrinkle fighter
The next big idea in preventing wrinkles is very, very small.

Ghost authorship of industry funded drug trials is common
Ghost authorship is the failure to name, as an author, an individual who has made a substantial contribution to a scientific article.

All in the family
Being a member of a large family may not be best for your health.

Study suggests hip fractures not caused by benzodiazepine use after all
Benzodiazepine use was not shown to be associated with hip fractures after all, according to a new study from the Department of Ambulatory Care and Prevention (of Harvard Medical School and Harvard Pilgrim Health Care).

Some patients dissatisfied following closed reduction of nasal fractures
In a small series of patients who underwent closed reduction, the standard procedure to repair a broken nose, nearly one-third reported dissatisfaction with the outcome and about one-third said they would consider further surgery to correct their nasal deformities, according to a report in the January/February issue of Archives of Facial Plastic Surgery, one of the JAMA/Archives journals.

Patients with amnesia 'live in the present'
Scientists at the Wellcome Trust Center for Neuroimaging, University College London, have shown that people with damage to the hippocampus, the area of the brain that plays a crucial role in learning and memory, not only have trouble remembering the past but also in imagining new and future experiences.

Review study finds association between tobacco smoking and increased risk of tuberculosis
Researchers from the Harvard School of Public Health (HSPH) found consistent evidence that smoking is associated with an increased risk of TB.

Combination therapy reduces exacerbations in severe COPD
For patients with severe chronic obstructive pulmonary disease (COPD), combining a long-acting bronchodilator with an inhaled corticosteroid reduced the number of exacerbations by 35 percent.

Should HIV-positive mothers breastfeed?
A new study conducted by Renaud Becquet and colleagues in Abidjan, Côte d'Ivoire, and reported in PLoS Medicine shows that if HIV-positive mothers are well supported, either of the two feeding options currently recommended (formula-only feed, or short-term breastfeeding) are likely to be equivalent in terms of the baby's chances for survival and health.

Outcomes comparable for younger and older children with surgically implanted hearing aids
Outcomes following surgically implanted hearing aids that are anchored to bone appear comparable for children younger than five years and those older than five years, according to a report in the January issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.

Low-dose aspirin offers lower chance of asthma
In a large, randomized, placebo-controlled study of 22,071 healthy male physicians, taking a low-dose of aspirin every other day lowered the risk of receiving an initial asthma diagnosis by 22 percent.

Cloudy apple juice four times healthier than clear
Cloudy apple juice has four times the concentration of polyphenols (chemicals reported to have anti-cancer activity) than clear.

Putting a face on the earliest modern Europeans
The earliest modern humans in Europe were not completely

New proteomic method to detect inflammation in amniotic fluid
A score that measures the proteomic profile of amniotic fluid may predict inflammation before delivery.

Common blood test can help distinguish between mononucleosis and tonsillitis
Measuring a patient's ratio of white blood cell types may help physicians accurately distinguish between the similar conditions infectious mononucleosis and bacterial tonsillitis, potentially guiding treatment decisions, according to an article in the January issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.

Association of tuberculosis with smoking and indoor air pollution
Smokers have an increased risk of tuberculosis (TB) infection, TB disease and of dying from TB compared to people who do not smoke.

Worried about prostate cancer? Tomato-broccoli combo shown to be effective
A new University of Illinois study shows that tomatoes and broccoli -- two vegetables known for their cancer-fighting qualities -- are better at shrinking prostate tumors when both are part of the daily diet than when they're eaten alone.

Study profiles rural individuals most likely to have recurrent trauma center admissions
About 3.4 percent of patients treated in rural trauma centers appear to be recidivists, meaning that they have visited the facility more than once for separate injuries, according to a report in the January issue of Archives of Surgery, one of the JAMA/Archives journals.

Webb scope looks out of this world
The James Webb Space Telescope (JWST), the orbiting infrared observatory designed to succeed the Hubble Space Telescope, is set to enable fundamental breakthroughs in our understanding of the formation and evolution of galaxies, stars and planetary systems.

Learning with a partner improves skin cancer self-examination practices
Individuals who received instruction on skin self-examination with their partners may be more likely to engage in this cancer prevention behavior, according to a report in the January issue of Archives of Dermatology, one of the JAMA/Archives journals.

Fewer patients undergoing stroke prevention surgery for wrong reasons
A new study has found a drop in the number of patients undergoing the most commonly used stroke prevention surgery, carotid endarterectomy, for inappropriate reasons.

Relationship between delirium and dementia
For the most part, dementia and delirium have been viewed as separate and distinct conditions.

Producing medicines in plant seeds
Using plants to produce useful proteins could be an inexpensive alternative to current medicine production methods.

Growth hormone is not the anti-aging bullet for healthy adults
A review of published data on use of human growth hormone by healthy elderly people found that the synthetic hormone was associated with small changes in body composition but not in body weight or other clinically important outcomes.

Microtubule protein interactions visualized en masse
Previously unknown interactions between different microtubule- associated proteins (MAPs) are identified via a new technique, termed visual immunoprecipitation.

Risk of death increases with combined heart and stroke prevention surgery
Patients who undergo combined heart bypass surgery and carotid endarterectomy, the most commonly used stroke prevention surgery, significantly increase their chances of death or stroke, according to a study published in the January 16, 2007, issue of Neurology®, the scientific journal of the American Academy of Neurology.

$2.9M NIH grant expands successful parenting education program of Rush University
A record $2.9 million grant will help Rush University College of Nursing faculty to reach out to parents struggling with their children's behavior problems.

No proof that growth hormone therapy makes you live longer, Stanford study finds
Surveyors of anti-aging elixirs tout human growth hormone as a remedy for all things sagging-from skin to libidos -- and claim it can even prevent or reverse aging.

New study to test statin-Parkinson's link
Results of a recent study linking low LDL cholesterol to Parkinson's provide the strongest evidence to date that it could be real, because statins work by reducing LDL cholesterol.
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