Brightsurf Science News & Current Events

April 15, 2007
Novel antigen-cloning technique may boost efforts to develop a melanoma vaccine
Experimental vaccines to help the immune system fight tumors have rarely been designed to directly stimulate helper T cells, one of the body's most critical immune responders, because of the difficult process required to isolate and clone antigens for vaccine development.

MicroRNAs as tumor suppressors
In an upcoming Genes & Development paper, Drs. Yong Sun Lee and Anindya Dutta (UVA) reveal that microRNAs can function as tumor suppressors in vitro.

'Night owls' report more insomnia-related symptoms
Those persons who are labeled a

Mayo Clinic Cancer Center researcher finds mold by-product kills multiple myeloma
Mayo Clinic Cancer Center researchers have found that chaetocin, a by-product of a common wood mold, has promise as a new anti-myeloma agent.

Health disparities -- Genetics, society and race play an important role in access to healthcare
Minority individuals are much more likely to develop and die from cancer than the general US population.

Diseased brain cells more involved in ALS-associated motor neuron death
Two papers by Columbia and Harvard researchers report for the first time that astrocytes -- the most abundant non-neuronal cells in the central nervous system, which carry a mutated gene known to cause some cases of amyotrophic lateral sclerosis (ALS/Lou Gehrig's disease) -- induce motor neuron death.

Enhancing chemotherapy's efficacy: New agent has synergistic effect with standard drugs
Integrating the use of drugs targeted to specific cancer proteins into current chemotherapy regimens to improve the efficacy of systemic treatment is an important clinical goal.

Scientists find new genes for Crohn's disease
A consortium of US and Canadian researchers is reporting in today's online issue of Nature Genetics that they have discovered several more genetic variations that are strongly linked to an increased risk for the disease.

Mailman School of Public Health researchers report blood DNA can be early predictor of liver cancer
Researchers at Columbia University's Mailman School of Public Health have discovered a means for early detection of liver cancer.

Research team identifies additional genetic risk factors for Crohn's disease
An international research team has identified several novel genetic variations associated with the risk of Crohn's disease.

Diet and lifestyle -- In the cancer fight, eating well is the best revenge
We all know that eating fruits, vegetables and soy products provides essential nutrition for a healthy lifestyle, while obesity leads to the opposite.

Scientists find major susceptibility gene for Crohn's disease
Using a novel approach, researchers identified that the PHOX2B, NCF4 and ATG16L1 genes constitute genetic risk factors for Crohn's disease.

Researchers use smallest pipette to reveal freezing 'dance' of nanoscale drops
Using what is thought to be the world's smallest pipette, two researchers at the US Department of Energy's Brookhaven National Laboratory have shown that tiny droplets of liquid metal freeze much differently than their larger counterparts.

New imaging method shows whether treatment for advanced prostate cancer is working
Researchers at the University of Michigan Comprehensive Cancer Center have identified a new imaging technique that can measure the effectiveness of treatment for prostate cancer that has spread to the bones.

USC study identifies factors attributed to later stage cancer diagnosis
Researchers from the Keck School of Medicine of the University of Southern California found that patients who received a later stage cancer diagnosis were likely to be living in an unsafe neighborhood, using public transportation and traveling at least 45 minutes to get to a doctor's office.

New diagnostic technologies offer non-invasive means
Molecular messages and signals circulating in blood or contained in cells lining the airway can identify early stage cancer, according to research reported today at the 2007 Annual Meeting of the American Association for Cancer Research.

Men who habitually consume alcohol more likely to have a sleep-related breathing disorder
Increased usual alcohol consumption among men is associated with an increased risk of a mild or worse sleep-related breathing disorder (SRBD).

Progress toward a targeted therapy for a specific form of leukemia
Leukemia strikes some 700 Belgians each year. Scientists are still searching for the cause of many forms of leukemia, including T cell acute lymphoblastic leukemia, or T-ALL.

Study links breast cancer risk to epigenetic changes related to race, smoking and birth size
Women can encounter environmental factors that increase their risk of breast cancer at various periods of their physical development, beginning before birth and extending until menopause.
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