Brightsurf Science News & Current Events

August 01, 2008
Lab study shows methadone breaks resistance in untreatable forms of leukemia
Researchers in Germany have discovered that methadone, an agent used to break addiction to opioid drugs, has surprising killing power against leukemia cells, including treatment resistant forms of the cancer.

Highlights from the August 2008 Journal of the American Dietetic Association
The August 2008 issue of the Journal of the American Dietetic Association contains articles and research studies you may find of interest.

Immunotherapy in high-risk pediatric sarcomas shows promising response
Based on a pilot study in children with sarcoma, researchers at the National Institutes of Health believe that immunotherapy could prove beneficial in treating high-risk forms of this cancer.

Ties to war-dead are a predictor of likely presidential disapproval
Those who know someone who died in the Iraq War or 9/11 terrorist attacks are less likely to approve of President Bush's performance in office than people who have no such connections, according to new research from the University of California, Davis.

Immune system protein accurate predictor of survival in pediatric septic shock
A simple measure of an immune system protein within 24 hours of being admitted to the hospital for septic shock can predict survival in children, yielding a powerful tool for diagnostics and clinical trials of new septic shock therapies, according to a research team led by Cincinnati Children's Hospital Medical Center in the Aug.

When our protective armor shows weakness
In a large study on more than 3,000 school-children scientists of the Helmholtz Zentrum München and the Technische Universität München found that about 8 percent of the German population carry variations of the filaggrin gene, which raise the risk to develop atopic dermatitis more than threefold.

New male circumcision device for HIV prevention studied by NewYork-Presbyterian/Weill Cornell
With the recent endorsement by the World Health Organization and scientists worldwide of adult male circumcision as an important strategy for HIV prevention, there is increased urgency to develop safe and cost-effective circumcision services.

A mechanism for the development of obesity-associated conditions
Substances known as endocannabinoids have been implicated in the development of many effects of a high-fat diet, including risk factors for type 2 diabetes.

'Convenience' of screening mammography facilities plays major role in patient retention
Patients cite

Long work hours widen the gender gap
Working overtime has a disproportionate impact on women in dual-earner households, exacerbating gender inequality and supporting the

NIDDK publishes new resources about urologic and kidney disorders
The National Institute of Diabetes and Digestive and Kidney Diseases at the National Institutes of Health has published several new resources to help people learn more about urologic and kidney disorders.

Overcoming inhibitors of cell death improves cancer therapy efficacy
Individuals with one of the most aggressive types of brain tumor have an extremely poor prognosis.

Allergic-like reactions to iodinated contrast material treated safely with commonly used medications
Patients who have had acute allergic-like reactions to nonionic iodinated contrast material rarely develop any serious long-term problems and can be treated safely with commonly used medications according to a recent study conducted by researchers at the University of Michigan Hospitals in Ann Arbor.

Australian study shows that sleep apnea is an independent risk factor for mortality
Moderate to severe obstructive sleep apnea is an independent risk factor for all-cause mortality, represented by a fully adjusted hazard ratio of 6.24.

Study shows that people with sleep apnea have a high risk of death
Adults in the general population who have severe sleep apnea have three times the risk of dying due to any cause compared with people who do not have sleep apnea, and this risk increases when sleep apnea is untreated.

JDRF announces 2008 Scholar Award recipients
JDRF said today that it has recognized the work of two top diabetes researchers who are focused on accelerating the pace of science in understanding the autoimmune attack that causes type 1 diabetes, and on preventing or reversing the severe complications of this chronic and life-threatening disease.

Guilt on their hands: tiny 'tags' could help to solve and deter gun crime
Criminals who use firearms may find it much harder to evade justice in future, thanks to an ingenious new bullet tagging technology developed in the UK.

JCI online early table of contents: Aug. 1, 2008
This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, Aug.

In Vietnam, alongside progress, a battle for life
Behind the elegant French colonial-style exterior of the National Cancer Hospital in Hanoi, the capital of Vietnam, a battle is raging.

China becomes a physics powerhouse
Judged by the astonishing increase in journal papers written by scientists in China, there can be little doubt that China is finding its place as one of the world's scientific power houses.

Recurrence of group B strep high in subsequent pregnancies, say UT Houston obstetricians
A new study by researchers at the University of Texas Medical School at Houston could help experts better decide whether to continue the current practice of retesting women during their second pregnancies for a common bacterial infection if they had tested positive for the infection previously.

Disaster medicine ethical guidelines needed for US health-care professionals
A new invited article in the August 2008 edition of Otolaryngology - Head and Neck Surgery calls on the US medical community to develop a national consensus on ethical guidelines for physicians who care for patients, victims, and casualties of disasters such as hurricanes, tornadoes, floods or terrorist attacks.

Once-daily atazanavir/ritonavir as effective as lopinavir/ritonavir twice-daily in HIV patients
In treatment-naive patients with HIV, atazanavir/ritonavironce daily shows similar antiviral efficacy to twice daily.

Superfluid-superconductor relationship is detailed
Scientists have studied superconductors and superfluids for decades. Now, researchers at Washington University in St.

Penn researchers find a new role for a 'Foxy Old Gene'
Researchers at the University of Pennsylvania School of Medicine have discovered that a protein called FOXA2 controls genes that maintain the proper level of bile in the liver.

Chronic exposure to estrogen impairs some cognitive functions
Researchers report this week that chronic exposure to estradiol, the main estrogen in the body, diminishes some cognitive functions.

Highlights from the August 2008 issue of Ophthalmology
The August issue of Ophthalmology, the journal of the American Academy of Ophthalmology, includes surprising findings on Asian ethnicity and macular degeneration and on nearsightedness in school children, as well as a study of successful treatments for ocular surface cancer.

Nano sculptures in gold
Scientists in Berlin are using a new method to resolve the structure of uncharged gold nano particles.

Strategies to control TB outdated, inadequate
The standard regimens to treat tuberculosis are inadequate in countries with high rates of multi-drug resistant TB.

Spanish researchers discover significant leatherback turtle nesting beaches in the Caribbean
A scientific project funded by the BBVA Foundation and conducted by a team from CSIC explored 100 kilometers of practically uncharted Atlantic beach in the north of Colombia and south of Panama.

Disparities in prostate cancer treatment suggest ways to improve care
Quality of care varies greatly for the treatment of men with early-stage prostate cancer by region of the country and category of health care facility, suggesting the potential for improved patient outcomes with more standard treatment protocols, according to a new study that was published in the Aug.

No substitute for hard work: Creatine supplementation does not improve exercise outcomes in COPD
Creatine, a popular nutritional supplement renowned for enhancing athletic performance and muscle strength, does not improve exercise outcomes in patients with chronic obstructive pulmonary disease, according to a new study.

Many 'failing' schools aren't failing when measured on impact rather than achievement
Up to three-quarters of US schools deemed failing based on achievement test scores would receive passing grades if evaluated using a less biased measure, a new study suggests.

Survival of the fittest: even cancer cells follow the laws of evolution
Scientists discovered the underlying process in tumor formation is the same as for life itself --evolution.

2 years old -- a childhood obesity tipping point?
This study finds that obese children begin weight gain as infants, with more than half becoming obese before two years of age.

Combating secondary infections in clinics
Infections following treatment are a grave problem for patients, and resistant germs can be particularly devastating.

Turned-off cannabinoid receptor turns on colorectal tumor growth
New preclinical research shows that cannabinoid cell surface receptor CB1 plays a tumor-suppressing role in human colorectal cancer, scientists report in the Aug.

Cutting the brakes on the immune system
A new study by Patrick Gaffney, M.D., and Kathy Moser, Ph.D., of the Oklahoma Medical Research Foundation has found that variation of a particular gene -- known as TNFAIP3 -- may cause the immune system to lose its ability to shut off, leading to the autoimmune disease lupus.

Tracking down abrupt climate changes
Extremely fast climate change in Western Europe. This took place long before man-made changes in the atmosphere commenced.

NIDDK resource helps guide women with diabetes through healthy pregnancies
Pregnancy is a time of great excitement and anticipation. It also can be a time of anxiety, especially for women with type 1 or type 2 diabetes.

Sleep apnea linked to increased risk of death
Sleep-disordered breathing (also known as sleep apnea) is associated with an increased risk of death, according to new results from the Wisconsin Sleep Cohort, an 18-year observational study.

The emerging scientific discipline of aeroecology
Aeroecology is the emerging discipline for studying how airborne organisms -- birds, bats, arthropods and microbes -- depend on the support of the lower atmosphere that is closest to the Earth's surface.

'Office of the future' environment study
Mayo Clinic endocrinologist James Levine, M.D., Ph.D., has continued his research in environment-changing innovations with a six-month study of a real-life office that was re-engineered to increase daily physical activity or NEAT (non-exercise activity thermogenesis).

The brightest, sharpest, fastest X-ray holograms yet
An international group of scientists working at the Advanced Light Source (ALS) at DOE's Lawrence Berkeley National Laboratory, and at FLASH, the free-electron laser in Hamburg, Germany, has produced two of the brightest, sharpest x-ray holograms of microscopic objects ever made, thousands of times more efficiently than previous x-ray-holographic methods.

Size-specific cracking shakes
Certain sizes of nanostructures may be more susceptible to failure by fracture than others.

Innovative diabetes program in Bloomington-Normal, Ill., a success
Diabetes Checks & Balances, a unique program launched locally to help people manage the disease, helped decrease emergency room visits and hospital admissions among participants.

Higher HIV infection estimate shows need for routine screening, more funding for care
The Centers for Disease Control and Prevention is expected soon to increase the estimate of new HIV infections in the United States by 40 percent.

GKSS membranes reduce air pollution in Beijing
In China, new legal regulations prescribe the recovery of petrol vapour at filling stations (vent processing) in especially polluted regions like Beijing or Shanghai.

Multiple Sclerosis: new MRI contrast medium enables early diagnosis in animal model
In an animal model of multiple sclerosis, neuroradiologists and neurologists of the University hospitals of Heidelberg and Würzburg have been able to visualize inflammatory tissue damage, most of which had remained unrecognized up to now, with the aid of a new contrast medium, Gadofluorine M, in magnetic resonance imaging.
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