Brightsurf Science News & Current Events

August 31, 2008
Analysis of past glacial melting shows potential for increased Greenland ice melt and sea level rise
Researchers have yet to reach a consensus on how much and how quickly melting of the Greenland Ice Sheet will contribute to sea level rise.

New approach, old drug show promise against hepatitis C, Stanford research shows
Using a novel technique, medical and engineering researchers at Stanford University have discovered a vulnerable step in the virus' reproduction process that in lab testing could be effectively targeted with an obsolete antihistamine.

Ice Age lesson predicts a faster rise in sea level
If the lessons being learned by scientists about the demise of the last great North American ice sheet are correct, estimates of global sea level rise from a melting Greenland ice sheet may be seriously underestimated.

Telmisartan modestly reduces cardiovascular events in patients unable to tolerate ACE inhibitors
The angiotensin-receptor blocker telmisartan should be regarded as a potential treatment for vascular disease or high-risk diabetes, in the 20 percent of patients who are unable to tolerate the standard treatment of angiotensin-converting enzyme (ACE) inhibitors.

Genetic testing?
Sudden cardiac death is a major contributor to mortality in industrialized nations, affecting ~500,000 individuals annually in the Western world, and causing more deaths than AIDS, lung and breast cancer and stroke together.

Best use of drug-eluting stents
Compared with bare metal stents, drug-eluting stents substantially reduce the risk of angiographic and clinical recurrence but do not affect mortality or the short term or long term risk of myocardial infarction.

Sex hormones link to heart risk
New research led by University of Leicester into why men are more prone to heart disease.

Randomized trial shows omega-3 polyunsaturated fatty acids reduce mortality and hospital admission
A simple, safe, one-a-day capsule of omega-3 polyunsaturated fatty acids can reduce mortality and admission to hospital for cardiovascular reasons in patients with heart failure.

TIME-CHF trial: Elderly HF patients do not benefit from intensive medical therapy
Intensified, BNP-guided therapy was no more effective than a standard, symptom-guided approach in elderly heart failure patients in reducing the number of deaths and all-cause hospitalizations.

Who needs surgery?
Since 2000 the ratio of PCI: CABG has increased from 1:1 to almost 3:1.

Fluvastatin XL use is associated with improved cardiac outcome after major vascular surgery
The DECREASE III Study which took place in the Netherlands between June 2004 and April 2008, showed that patients treated with fluvastatin showed an improved cardiac outcome after surgery.

An international study led by Canadian researchers has found that telmisartan, a medication used to lower blood pressure, reduced the outcome of cardiovascular death, heart attack or stroke in people who are unable to tolerate a widely available and effective standard treatment.

DES in diabetic patients
Diabetes is increasingly viewed as a coronary artery disease equivalent.

Computed tomography provides anatomy -- we need ischemia!
CTA may facilitate management of symptomatic patients with low pre-test likelihood of CAD, in particular by conclusively showing absence of CAD.

Positive exercise testing in athletes: What does that mean?
In competitive athletes under 35 years of age with a high-risk profile for future cardiovascular events, an exercise test is mandatory to rule out/confirm the presence of underlying ischemic heart disease.

Sports-related sudden cardiac death is reduced by pre-participation cardiovascular screening
The introduction in Italy in 1982 of a nationwide pre participation screening program considerably reduced sudden cardiac death in young competitive athletes.

The future of non-invasive cardiac imaging
Imaging has gained attention in many areas of medicine but its relevance and importance in clinical cardiology cannot be underestimated.

Cardiac imaging in 2020
An emerging discipline of noninvasive cardiac imaging, molecular imaging, has evolved constantly in the last few years and is increasingly being translated from the preclinical to the clinical level.

Neurogenesis in the adult brain: The association with stress and depression
At the 21st Congress of the ECNP 2008 in Barcelona, Professor Fuchs from the Clinical Neurobiology Laboratory, German Primate Center in Goettingen, presented the latest findings on how brain cells can be adversely affected by stress and depression.

Landmark study opens door to new cancer, aging treatments
Researchers at the Wistar Institute have deciphered the structure of the active region of telomerase, an enzyme that plays a major role in the development of nearly all human cancers.

Researchers locate geographic origins from DNA
A study to be published online in Nature by an international team that included Cornell University and UCLA researchers describes the use of DNA to predict the geographic origins of individuals from a sample of Europeans, often within a few hundred kilometers of where they were born.

LEADERS (Limus Eluted from A Durable versus ERodable Stent coating)
In the first study of its kind, a drug-eluting stent with a biodegradable polymer applied only to the outer surface has been demonstrated as safe and effective as one of the most established and widely used types of DES with a durable polymer, in equivalent conditions to everyday clinical practice.

DES: New elements in the debate
Existing data indicate that there are important differences between various types of stents, with dissimilar mechanical and pharmacological properties and subsequent differences in clinical outcome.

The GISSI-HF trial
Researchers involved in the GISSI trial, concluded that simple, safe and cheap treatment with n-3 PUFA can provide a moderate beneficial advantage in terms of mortality and admission to hospital for cardiovascular reasons in patients with chronic heart failure, in a context of usual care.

New sensory devices will aid Parkinson's and stroke patients
People who have suffered a stroke or who have been diagnosed with Parkinson's disease, could benefit from new research at Queen's University Belfast.

The GISSI-HF trial: Effects of rosuvastatin in 4,574 patients with chronic heart failure
The GISSI-HF trial found rosuvastatin (10 mg daily) did not affect clinical outcomes in patients with chronic heart failure of any cause, in whom the drug seemed to be safe.

Global study shows telmisartan reduces outcome of cardiovascular death, heart attack or stroke
An international study led by Canadian researchers has found that telmisartan, a medication used to lower blood pressure, reduced the outcome of cardiovascular death, heart attack or stroke in people who are unable to tolerate a widely available and effective standard treatment.

The results of the much awaited BEAUTIFUL trial have shown that coronary artery disease patients with left ventricular dysfunction and a heart rate more than 70 bpm have a significantly higher risk of cardiovascular death and other cardiovascular events and in these patients (heart rate above 70 bpm) treatment with ivabradine further reduces the risk of the most important coronary events.

Cardiac ultrasound imaging goes to handheld
Non-invasive imaging has revolutionized the diagnosis of the most common cardiac diseases such as valve problems and coronary heart disease.

New master switch found in the brain that regulates appetite and reproduction
Body weight and fertility have long known to be related to each other -- women who are too thin, for example, can have trouble becoming pregnant.

Ivabradine reduces incidence of coronary artery disease outcomes in patients with high heart rate
Use of the heart-rate lowering drug ivabradine can reduce the incidence of cardiovascular disease and death in patients with coronary artery disease and a high heart rate.

New genes found for inflammatory bowel disease in children
Researchers have discovered two new genes that increase the risk of developing inflammatory bowel disease in childhood.

US union membership up substantially in 2008, study shows
Buoyed by a rising tide in California in general and Southern California in particular, US unionization levels rose substantially this year, defying a decades-long trend of decline, according to a report by UCLA's Institute for Research on Labor and Employment.

The ECNP consensus statement on bipolar depression
The highlights of the recently published ECNP consensus statement on bipolar depression were presented by the renowned British researcher Guy M.

Should we use echocardiography to screen young athletes?
Studies conducted in Italy suggest that a pre participation program, including echocardiography, is an efficient way to identify young athletes with cardiac disease. is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to