Brightsurf Science News & Current Events

September 01, 2008
Value of direct-to-consumer drug advertising oversold, study finds
In the first-ever controlled study measuring the effectiveness of pharmaceutical direct-to-consumer advertising, researchers found only a modest effect on drug sales.

Issues on cholesterol: Diet, statins and genetics
Genetic lipoprotein disorders are frequently seen in patients with premature coronary artery disease.

Children of older fathers more likely to have bipolar disorder
Older age among fathers may be associated with an increased risk for bipolar disorder in their offspring, according to a report in the September issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

PET scans help identify mechanism underlying seasonal mood changes
Brain scans taken at different times of year suggest that the actions of the serotonin transporter -- involved in regulating the mood-altering neurotransmitter serotonin -- vary by season, according to a report in the September issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

Risks and benefits of antipsychotics in children and adolescents
At the 21st Congress of the ECNP 2008 in Barcelona, Dr.

Children's calorie expenditure, heart rate increase during active video games
Children burn more than four times as many calories per minute playing an active video game than playing a seated game, and their heart rate is also significantly higher with the active game, according to a report in the September issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

Fraunhofer in Korea -- trends for mega cities
Seoul, the capital of South Korea, is a typical mega city: vast, pulsating, noisy and full of exhaust fumes.

New discovery about growth factor can be breakthrough for cancer research
A research team at the Ludwig Institute and Uppsala University has discovered an entirely new signal path for a growth factor that is of crucial importance for the survival and growth of cancer cells.

New diagnostic tools and biomarkers
New biomarkers allow improved diagnosis of patients presenting shortness of breath.

Advances in the management of patients with diabetes mellitus: Triumphs and tragedies
Disappointing results of latest treatments of blood glucose which have not convincingly reduced problems, apart from sub-clinical micro-vascular disease.

Building bridges to the Far East
Korea is in the ascendant. Its economy is booming, and products made in Korea are available all over the world.

BioScience tip sheet, September 2008
The press release lists research articles that will be published in the September 2008 issue of BioScience and provides a brief description of each one.

Anti-angiogenic and anti-inflammatory drugs: Are they safe?
Since rofecoxib was withdrawn from the worldwide market based on the safety findings of the APPROVe study, the uncertainty around the cardiovascular safety of NSAIDs and COX-2 inhibitors remains and leaves practitioners with difficult management decisions for the hundreds of millions of patients worldwide who continue to require pain-relieving therapy to maintain an acceptable quality of life.

Impact of school-based programs
Childhood overweight and obesity are serious, large-scale, global, public health concerns and the number of children affected is still increasing every year.

Water: stressed-out and overheated
Water is the basis of all life on earth, yet freshwater animals and plants are being lost faster than in any other ecosystem.

Prehistoric funerary precinct excavated in northern Israel
Hebrew University excavations in the north of Israel have revealed a prehistoric funerary precinct dating back to 6,750-8,500 BCE.

Does treatment of depression improve prognosis after heart attack?
Depression and heart disease are the two leading disorders with the strongest contributions to the global burden of disease.

Family therapy helps relieve depression symptoms in bipolar teens
Family-focused therapy, when combined with medication, appears effective in stabilizing symptoms of depression among teens with bipolar disorder, according to a report in the September issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

Embargoed clinical news from Annals of Internal Medicine
This release contains information about three studies being published in the Sept.

American Chemical Society's Weekly PressPac -- Aug. 27, 2008
The American Chemical Society News Service Weekly Press Package contains reports from 36 major peer-reviewed journals on chemistry, health, medicine, energy, environment, food, nanotechnology and other hot topics.

Wolves would rather eat salmon
Although most people imagine wolves chasing deer and other hoofed animals, new research suggests that, when they can, wolves actually prefer fishing to hunting.

Global warming greatest in past decade
Researchers confirm that surface temperatures in the Northern Hemisphere were warmer over the last 10 years than any time during the last 1300 years, and, if the climate scientists include the somewhat controversial data derived from tree-ring records, the warming is anomalous for at least 1700 years.

Robotic navigation systems in electrophysiology
Catheter ablation is still associated with a substantial amount of complications, and more failure then sometimes reported.

Anastrozole does not impair cognition in postmenopausal women at risk of breast cancer
Daily anastrozole therapy given to postmenopausal women who are at high risk of breast cancer, with the intention of preventing breast cancer occurrence, does not cause impairment of cognitive performance after 24 months of treatment, concludes a substudy of the International Breast Intervention Study (IBIS II), published early online, and in the October edition of the Lancet Oncology.

Experts to share how research is tackling cancer
Cancer touches many people, but few have the chance to meet the researchers who have dedicated their lives to tackling the disease.

Scientists find second site for prostate cancer gene
Scientists at Wake Forest University School of Medicine and colleagues who are studying a prostate cancer gene called HNF1B have found a second independent site within the HNF1B gene on chromosome 17 (17q12) -- increasing the number of genetic variants that may contribute to risk of developing the disease.

Bowling alone because the team got downsized
The pain of downsizing extends far beyond laid off workers and the people who depend on their paychecks, according to a new UCLA-University of Michigan, Ann Arbor study.

Periodic limb movement during sleep is less common in African-Americans; associated with insomnia
A study in the Sept. 1 issue of the journal Sleep is the first to objectively determine the prevalence of periodic limb movements during sleep in a population-based sample, finding a lower prevalence of PLMS in African-Americans and a higher rate of insomnia complaints in people with PLMS.

Brain imaging links chronic insomnia to reversible cognitive deficits without changes in behavior
A neuroimaging study in the Sept. 1 issue of the journal Sleep is the first to find that cognitive processes related to verbal fluency are compromised in people with insomnia despite the absence of a behavioral deficit.

Noninvasive test accurately identifies advanced liver disease without biopsy
Noninvasively measuring liver stiffness with transient elastography accurately diagnoses patients with late-stage liver disease, reports a new study in Clinical Gastroenterology and Hepatology.

Study shows heavy snoring is an independent risk factor for carotid atherosclerosis
A study in the Sept. 1 issue of the journal Sleep shows that objectively measured heavy snoring is an independent risk factor for early carotid atherosclerosis, which may progress to be associated with stroke.

Study shows subjective sensitivity skin temperature change is decreased in older insomniac adults
A study in the Sept. 1 issue of the journal Sleep shows that the subjective interpretation of temperature change is decreased in older adults, particularly those who suffer from insomnia.

TGen and Washington University researchers discover new approach to treating endometrial cancer
Researchers at the Translational Genomics Research Institute today announced a new approach to treating endometrial cancer patients that not only stops the growth of tumors, but kills the cancer cells.

Survey: 'Tanorexia' common among university students
A new study conducted at a large university finds more than 25 percent of those surveyed reported symptoms of tanning dependence, including symptoms similar to alcohol and drug-addicted individuals.

Graphene pioneers follow in Nobel footsteps
Two physicists from the University of Manchester who discovered the world's thinnest material have scooped a major award for their work.

Biomarkers for ischaemia and necrosis -- simple blood tests to detect myocardial infarction
In conjunction with clinical assessment and the ECG, simple and rapid blood tests have become the standard for the detection of myocardial infarction.

Depression common among Rwandan youth who head households
More than half of orphaned youth age 12 to 24 who head households in rural Rwanda meet criteria for depression, according to a report in the August issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

The first autism disease genes
At the 21st Congress of the ECNP 2008 in Barcelona, professor Marion Leboyer, University of Paris, France, presented the compelling neurobiological story of discovering the first autism genes.

Playing, and even watching, sports improves brain function
Being an athlete or merely a fan improves language skills when it comes to discussing their sport because parts of the brain usually involved in playing sports are instead used to understand sport language, new research at the University of Chicago shows.

Thawing permafrost likely to boost global warming
A new assessment more than doubles previous estimates of the amount of carbon stored in permafrost, and indicates that carbon dioxide emissions from microbial decomposition of organic carbon in thawing permafrost could amount to roughly half those resulting from global land-use change during this century.

Transcatheter aortic valve replacement -- a new frontier in cardiovascular medicine
Replacing heart valves without the substantial trauma of opening the chest and the heart were little known concepts until the groundbreaking pulmonary and aortic transcatheter valve replacements performed during 2000 and 2002, respectively by Philipp Bonhoeffer and Alain Cribier.

Connolly tells Manchester conference: Tutankhamen fathered twins
Two fetuses found in the tomb of Tutankhamen may have been twins and were very likely to have been the children of the teenage Pharaoh, according to the anatomist who first studied the mummified remains of the young King in the 1960s.

Transapical aortic valve implantation
Transapical aortic valve implantation is a new therapeutic strategy, which has been implemented successfully into clinical practice in several hundred patients suffering symptomatic aortic stenosis and an increase perioperative risk during the past two years.

Biosensors DES demonstrates equivalent safety and efficacy to industry leading DES
Biosensors International Group, Ltd. today announced that a next-generation drug-eluting stent, developed by Biosensors, has demonstrated equal safety and efficacy as compared to Johnson & Johnson's industry leading drug-eluting stent, CYPHER SELECT, based upon nine-month clinical and angiographic follow-up data.

New biolimus stents, biodegradable polymer are as effective as sirolimus stents and durable polymer
Stents eluting biolimus from a biodegradable polymer represent a safe and effective alternative to a stent eluting sirolimus from a durable polymer in patients with chronic stable coronary artery disease or acute coronary syndromes.

More daytime sleeping predicts less recovery during rehabilitation for older adults
A study in the Sept. 1 issue of the journal Sleep shows that daytime sleeping during a rehabilitation stay predicts less functional recovery for older adults, with effects lasting as long as three months.

Higher anaphylaxis rates after HPV vaccination: CMAJ study
The estimated rate of anaphylaxis in young women after human papillomavirus (HPV) vaccination was significantly higher -- 5 to 20 fold -- than that identified in comparable school-based vaccination programs, according to a study published in CMAJ.

Study examines relationship between low birth weight and psychiatric problems in children
Low-birth-weight children appear to be at higher risk for psychiatric disturbances from childhood through high school than normal-birth-weight children, according to a report in the September issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

Hospitals provide formula sample packs while medical organizations encourage breastfeeding
A majority of US hospitals on the East coast distribute formula sample packs to new mothers, contrary to recommendations from most major medical organizations concerned about the potential for distributing these packs to reduce breastfeeding rates, according to a report in the September issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

Academic health centers should take lead in promoting the sharing of biomedical research data
Academic health centers have a critical role in enabling, encouraging and rewarding the sharing of biomedical research data, say a team of academics in this week's PLoS Medicine.

World Cancer Declaration sets ambitious targets for 2020
A summit of more than 60 high-level policymakers, leaders and health experts have adopted a global plan aimed at tackling the growing cancer crisis in developing countries.

BUSM researchers observes asymptomatic carotid plaque healing mechanisms
Researchers at Boston University School of Medicine have observed a noninvasive MR imaging a healing mechanism for plaque rupture, a potentially life-threatening event in the cardiovascular system that can result in a fatal heart attack or debilitating stroke.

How often do hip and knee replacements need revision?
A comprehensive study using nationwide data on hip and knee replacements in England has found that one in 75 patients require a revision of their joint replacement after three years.

Percutaneous mitral valve repair
The scope of percutaneous cardiac therapy has expanded from percutaneous coronary and peripheral intervention to percutaneous valve intervention, first used in the mid eighties.

Intima media thickness of the carotid artery
Both in the clinic and in the research area we look for a toll to identify subjects who will develop cardiovascular disease.
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