Brightsurf Science News & Current Events

October 26, 2009
Study reveals possible link between IBD therapy and skin cancer
Findings from a new retrospective cohort study indicate that patients with Inflammatory Bowel Disease, especially those receiving the thiopurine class of medications to treat IBD, may be at risk for developing nonmelanoma skin cancer.

Wild pigs and deer do not spread GM corn via feces or accumulate transgenic residues in meat
The German Federal Agency for Nature Conservation funded a study to address two controversial questions: When wild boar and deer, traditional menu items in the fall, eat genetically modified corn, do transgenic residues accumulate in their meat?

Scientists identify a cellular pathway by which alcohol may promote cancer progression
Epithelial-mesenchymal transition (EMT) is essential for numerous developmental processes involving biological cells.

Latest analysis confirms suboptimal vitamin D levels in millions of US children
A new study appearing in the upcoming Pediatrics suggests that children between the ages of 1 and 11 may suffer from optimal levels of vitamin D, and black and Hispanic children are particularly at risk.

Engineering center to probe forces that cause cancer to spread
Researchers from the Johns Hopkins Institute for NanoBioTechnology have been awarded $14.8 million from the National Cancer Institute to launch a research center aimed at unraveling the physical underpinnings of the growth and spread of cancer.

Scientists discover gene that 'cancer-proofs' rodent's cells
Despite a 30-year lifespan that gives ample time for cells to grow cancerous, a small rodent species called a naked mole rat has never been found with tumors of any kind -- and now biologists at the University of Rochester think they know why.

Mayo Clinic study shows people with heart devices can 'digest' advanced diagnostic technology safely
A new Mayo Clinic study suggests that video capsule endoscopy, a procedure that uses wireless technology in diagnosing intestinal disease, is safe for patients with heart devices.

Combination antiretroviral therapy effective at reducing HIV resistance in mothers and babies following mother-to-child transmission
In a clinical trial investigating mother-to-child HIV transmission in South Africa published this week in PLoS Medicine, Neil Martinson and colleagues find that adding two other antiretroviral drugs to single dose nevirapine -- an antiretroviral drug given to women and newborn children during labor and delivery to prevent transmission -- is effective in reducing the drug resistance that nevirapine causes when used by itself.

AMD drug and IOP; getting good eyeglasses to those in need
A first-time finding of intraocular pressure increases in patients with no personal or family history of glaucoma following anti-VEGF treatment for wet age-related macular degeneration (AMD), and a report on a simple, low-cost method that could revolutionize vision screening and treatment in developing countries, are highlights of today's Scientific Program of the 2009 Joint Meeting of the American Academy of Ophthalmology and the Pan-American Association of Ophthalmology.

Examining genetic variations among the Huichol population of Mexico
Mexican researchers examined the polymorphisms of three enzymes -- alcohol dehydrogenase (ADH1B), aldehyde dehydrogenase (ALDH2) and cytochrome P4502E1 (CYP2E1) -- in the Mestizo and Huichol groups.

AGU Journal highlights -- Oct. 26, 2009
Featured in this release are research papers on the following topics:

Will genomics help prevent the next pandemic?
This week, the Public Library of Science, an open-access publisher, presents the

Physical scientists at Arizona State University will apply laws of physics in cancer fight
Instead of killing cancer cells, researchers at Arizona State University will use the laws of physics to figure out how to control them.

Blue light-filtering increases macular pigment, may protect against age-related vision loss
A new study shows that implantation of blue light-filtering intraocular lens at the time of cataract surgery increases a nutritional component of the eye, which may afford protection against the development and/or progression of age-related macular degeneration.

Weather patterns help predict dengue fever outbreaks
High temperatures, humidity and low wind speed are associated with high occurrence of dengue fever according to a study published in the open-access journal BMC Public Health.

NCI awards $15.2 million to create Princeton Physical Sciences -- Oncology Center
Princeton University physical scientists will partner with researchers at four other institutions to explore the driving forces behind the evolution of cancer under a five-year, $15.2 million award from the National Cancer Institute.

Holocaust survivors at higher risk for all cancers
Jewish survivors of World War II who were potentially exposed to the Holocaust are at a higher risk for cancer occurrence, according to a new study published online Oct.

Review of NASA's pilot safety survey
A new report from the National Research Council,

Emerging imaging modalities impact diagnosis of digestive disease
Several studies on new colonoscopic technologies reveal some imaging modalities fare better than others at improving detection of potentially pre-cancerous growths in the colon known as adenomas.

Exercise makes cigarettes less attractive to smokers
Exercise can help smokers quit because it makes cigarettes less attractive.

Novel findings shed light on how N-type channel function is modified by lipids
The November 2009 issue of the Journal of General Physiology contains two papers by the Rittenhouse laboratory that describe novel findings on how N-type voltage-gated calcium channel function is modified by lipids.

Researchers discover mechanism that prevents 2 species from reproducing
Cornell researchers have discovered a genetic mechanism in fruit flies that prevents two closely related species from reproducing, a finding that offers clues to how species evolve.

Increase in Down syndrome offset by better screening
The number of Down syndrome pregnancies has risen sharply over the last 20 years as women have opted to have children later, according to new research.

First evidence for a second breeding season among migratory songbirds
Biologists for the first time have documented a second breeding season during the annual cycle of five songbird species that spend summers in temperate North America and winters in tropical Central and South America.

Roth IRA conversion not a good fit for all, tax expert says
Starting next year, anyone can convert retirement savings into tax-advantaged Roth individual retirement accounts, but the much-touted switch isn't for everyone, a University of Illinois expert on tax and elder law warns.

Fighting sleep, Penn researchers reverse the cognitive impairment caused by sleep deprivation
A research collaboration led by biologists and neuroscientists at the University of Pennsylvania has found a molecular pathway in the brain that is the cause of cognitive impairment due to sleep deprivation.

Study shows unsedated colonoscopy for colorectal cancer screening well accepted by patients
Researchers from Taiwan report in a new study that unsedated colonoscopy for primary colorectal cancer screening is well accepted in a majority of patients.

Probiotic found to be effective treatment for colitis in mice
The probiotic, Bacillus polyfermenticus, can help mice recover from colitis.

Nepotism has its benefits when it comes to survival
While nepotism may have negative connotations in politics and the workplace, being surrounded by your relatives does lead to better group dynamics and more cooperation in some animals.

UB study explores how women make decisions about breast cancer surgery
For women just diagnosed with breast cancer, one of the important decisions confronting them is whether to have a lumpectomy or mastectomy.

Wolves lose their predatory edge in mid-life, new U of Minnesota study shows
Although most wolves in Yellowstone National Park live to be nearly six years old, their ability to kill prey peaks when they are two to three, according to a study led by Dan MacNulty and recently published online by Ecology Letters.

Wellcome Trust funds dengue fever research in Leuven
The Laboratory for Virology and Experimental Chemotherapy and the Centre for Drug Design and Discovery at K.U.Leuven will receive a total of 2.8 million euro from the British Wellcome Trust.

Plastic Surgery 2009 news briefs
Plastic Surgery 2009 news briefs are designed to keep you up-to-date on embargoed studies and other news being presented at the annual meeting of the ASPS held Oct.

Deadly stomach infection rising in community settings, Mayo Clinic study finds
Mayo Clinic researchers have found that a sometimes deadly stomach bug, Clostridium difficile, is on the rise in outpatient settings.

Partners in weight loss success may help African-Americans shed more pounds
Enrolling in a weight loss program with a family member or friend appears to enhance weight loss among African-Americans, but only if the involved partner attends sessions frequently or also loses weight, according to a report in the Oct.

Changing behavior helps patients take medication as prescribed
Researchers at the University of Missouri found that applying behavior changing strategies, such as using pill boxes or reducing the number of daily doses, can improve patients' abilities to take their medications as required.

Common weed could provide clues on aging and cancer
A common weed and human cancer cells could provide some very uncommon details about DNA structure and its relationship with telomeres and how they affect cellular aging and cancer, according to a team led by scientists from Texas A&M University and the University of Cincinnati.

NASA gets a 3-D look at Neki becoming extra-tropical
NASA's Aqua and Tropical Rainfall Measuring Mission satellites are watching Tropical Storm Neki become extra-tropical, and TRMM data was used to create a three-dimensional image of the storm.

Breast cancer incidence in Spain drops in early 2000s after decades of increasing rates
After a steady increase of invasive breast cancer cases in Spanish women during the 1980s and 1990s, incidence rates abruptly declined starting in 2001 -- a trend most likely explained by a period effect linked to screening saturation, according to a new study published online Oct.

Teacher talk strains voices, especially for women
Teachers tend to spend more time speaking than most professionals, putting them at a greater risk for hurting their voices -- they're 32 times more likely to experience voice problems, according to one study.

IRSF receives $1 million matching gift
IRSF announced a major fundraising initiative titled

2009 Pearl Meister Greengard Prize goes to pioneering geneticist
The recipient of the 2009 Pearl Meister Greengard Prize is Australian geneticist Suzanne Cory, professor and former director of the Walter and Eliza Hall Institute of Medical Research.

Canadian cardiology team clears the way for lifesaving breast cancer treatment
A team of Canadian cardiologists, in collaboration with oncologists, are playing an important role in the war against breast cancer.

M. D. Anderson redefines screening guidelines for breast, cervical and colorectal cancers
Drawing on years of experience in cancer research and patient care, the University of Texas M.

Henry Ford Hospital study: Diverticulosis not associated with higher incidence of polyps
A Henry Ford Hospital study questions the need for aggressive screening for colonic polyps in patients with diverticulosis.

Alcohol activates cellular changes that make tumor cells spread
Alcohol consumption has long been linked to cancer and its spread, but the underlying mechanism has never been clear.

Vast majority of physicians satisfied with hospital chaplain services
A national survey of physicians' experience with hospital chaplains found that the vast majority of doctors were satisfied with the spiritual services provided.

FASTSAT instruments shipped to NASA Marshall for tests and launch preparation
Three of the satellite instruments that will fly on an upcoming satellite mission called

Slipper-shaped blood cells
Physicists investigate the forces that deform red blood cells into asymmetric slipper shapes, and strive to learn how the deformation is important in blood flow and various blood flow-related diseases.

New 'schizophrenia gene' prompts researchers to test potential drug target
Johns Hopkins scientists report having used a commercially available drug to successfully

Surgeons at Boston Medical Center offering new procedure for acid reflux/GERD
Boston Medical Center surgeons are now offering patients an incisionless alternative to laparoscopic and traditional surgery for treatment of acid reflux or GERD.

Henry Ford study: Drug used for neuropathic pain relieves discomfort from abdominal adhesions
Pregabalin, FDA-approved for neuropathic pain (pain caused by shingles and peripheral neuropathy), effectively reduced abdominal pain and improved sleep in women with adhesions, according to a Henry Ford study.

A nervous system drug-by-design
Prof. Hagit Eldar-Finkelman of Tel Aviv University is

National hydrological measurement facility funded by NSF
As part of an $890,000 grant from the National Science Foundation, University of Nevada -- Reno researcher and faculty member Scott Tyler will be developing a national community-user facility for environmental sensing to make state-of-the-art fiber-optic distributed temperature instrumentation and equipment available to researchers throughout the country.

Location of body fat affects risk of blood clots in men, women
The risk of life-threatening blood clots increases with obesity, but may also depend on the location of excess body fat and gender.

Iowa State researchers study materials, combustion, cancer with new 'T-ray' instrument
Iowa State University researchers are beginning to work with a new $500,000 terahertz ray instrument that provides a new way to measure and characterize materials.

Ocean acidification may contribute to global shellfish decline
Relatively minor increases in ocean acidity brought about by high levels of carbon dioxide have significant detrimental effects on the growth, development, and survival of hard clams, bay scallops, and Eastern oysters, according to researchers at Stony Brook University's School of Marine and Atmospheric Sciences.

A solution to Darwin's 'mystery of the mysteries' emerges from the dark matter of the genome
Why do crosses between two species often yield sterile or inviable progeny (for instance, mules emerging from a cross between a horse and a donkey)?

Advances in screening have offset an increase in Down syndrome
The number of diagnoses of Down syndrome has increased by almost three quarters from 1989-90 to 2007-08, largely due to the considerable increase in the number of older mothers over this period.

Genes that drive you to drink (but don't make you an alcoholic)
Your genetic make up may predispose you to drink more but may not increase your genetic risk for alcoholism.

Simple measures can yield big greenhouse gas cuts, scientists say
New technologies and policies that save energy, remove atmospheric carbon and limit greenhouse gas emissions are needed to fight global climate change -- but face daunting technological, economic and political hurdles, a Michigan State University scientist said.

Hutchinson Center to build first US cancer clinic and training center in Africa
Building on the strengths of two institutions separated by nearly 9,000 miles over two continents -- both renowned in their work in the fight against cancer -- the United States Agency for International Development has awarded a $500,000 grant to Fred Hutchinson Cancer Research Center to aid in the construction of the first American cancer clinic and medical-training facility in Africa.

Growing threat of substandard, counterfeit medicines addressed by new USAID-USP agreement
With substandard and counterfeit versions of medicines intended to treat life-threatening diseases such as malaria, HIV/AIDS and tuberculosis posing a growing threat throughout the developing world, the US Agency for International Development and the US Pharmacopeial Convention will expand their joint efforts to combat this menace by launching a new program over the next five years.

Whales are polite conversationalists
What do a West African drummer and a sperm whale have in common?

Ancient 'monster' insect offers Halloween inspiration
Just in time for Halloween, researchers have announced the discovery of a new, real-world

Battling cancer with engineering: NCI funds new $13 million cancer research center led by Cornell
Adding potent research firepower and fresh physical perspectives to combat cancer, the National Cancer Institute has funded the new Center on the Microenvironment and Metastasis, which will be headquartered at Cornell University.

New studies explore connection between high stress jobs and GI disorders
In a six year study of World Trade Center workers, researchers probed the connection between the high frequencies of GERD and mental health disorders reported among exposed workers during the post 9/11 cleanup.

According to a thesis, diet and hydration of sportspeople improve during competition
The main goal of this research was to determine the composition of the ingestion of a group of volunteer skiers, participants in the XXX Andrés de Regil BBK Trophy Mountain Trek and correlate them with their anthropometric blood parameters, and with the time obtained in the trials.

Music makes you smarter
Regularly playing a musical instrument changes the anatomy and function of the brain and may be used in therapy to improve cognitive skills.

Chemosensitivity of cancer cells depends on their protein dependency
Two different anti-apoptotic proteins support cancer cell survival via an identical mechanism, yet differ in their sensitivity to chemotherapeutic drugs, report Brunelle et al. in the Nov.

Heart attacks become more common but less often fatal in women
Heart attacks appear to have become more common in middle-aged women over the past two decades, but all women and especially those younger than 55 have recently experienced a greater increase than men in their chances of survival following such a heart event, according to two reports in the Oct.

Protein critical for insulin secretion may be contributor to diabetes
A cellular protein from a family involved in several human diseases is crucial for the proper production and release of insulin, new research has found, suggesting that the protein might play a role in diabetes.

NSF grant supports Rutgers-Camden program for science majors
Contrary to a national trend, more and more students at Rutgers University-Camden are signing up to major in math and science.

Researchers evaluate new bowel prep approaches
In a pilot study to evaluate the safety and efficacy of polyethelne glycol plus ascorbic acid compared to magnesium citrate for bowel preparation before colonoscopy, researchers found that overall colon preparation was excellent or good for the vast majority of those receiving either solution.

Survival after heart attack improves in younger women
In recent years, women, particularly younger women, experienced larger improvements in hospital mortality after myocardial infarction than men, according to a study published in the Oct.

Professors receive $4.6 million to study impact of climate change on potential biofuel source
Researchers at the University of Texas at Austin have received a $4.6 million grant to explore how switchgrass, a native prairie grass and promising source of biofuel, will fare under future climate change.

The largest congress worldwide on ion therapy in Heidelberg
The largest congress worldwide on the topic of particle or ion therapy -- radiation with heavy ions and protons -- has taken place in the fall of 2009 in Heidelberg.

Higher risk of GI diseases may mean more vigilance, earlier screenings for minorities
A new study indicates that female patients are being diagnosed with more right-side, or proximal, colon cancers compared to the population in general.

Diagnoses of fatigue in primary care patients
Patients who visit their family doctors for fatigue have a wide range of diagnoses yet the prevalence of serious illness was low, according to a Dutch study in CMAJ.

Strategies to reduce HIV treatment dropout rates: cost-effective and improve survival chances
In a study published this week in PLoS Medicine, Elena Losina and colleagues predict that strategies to reduce dropout rates from HIV treatment programs in resource-poor settings would substantially improve patients' chances of survival and would be cost effective.

Safety study of capsule endoscopy in patients with implantable cardiac devices finds no interference
Performing capsule endoscopy, using a miniature capsule that is swallowed to record and transmit images of the small intestine, is safe in patients with implantable cardiac devices such as pacemakers and implantable defibrillators, a new study shows.

Study reveals high death rates and short life expectancy among the homeless and marginally housed
Homeless and marginally housed people have much higher mortality and shorter life expectancy than could be expected on the basis of low income alone, concludes a study from Canada published on bmj.com today.

American Academy of Ophthalmology President leads alliance work to rebuild health care in Iraq
Dr. Brennan leads a team of dedicated American physicians working with Iraqi physicians to provide improved care as the country recovers from the traumas of war.

Volcanoes played pivotal role in ancient ice age, mass extinction
Researchers here have discovered the pivotal role that volcanoes played in a deadly ice age 450 million years ago.

Scientists discover, patent, sell waste-water tech
Sam Houston State University has applied for six federal patents, three of which have already been awarded, to protect the technology and engineering associated with a

DOE grant launches Carnegie Mellon initiative to automate discovery of astrophysical phenomena
Automated methods for discovering astrophysical phenomena by sifting through massive amounts of cosmological data are being developed by researchers at Carnegie Mellon University, Johns Hopkins University and the University of Washington under a new three-year, $1.6 million grant from the US Department of Energy.

Science at the petascale: Roadrunner results unveiled
The world's fastest supercomputer, Roadrunner, at Los Alamos National Laboratory has completed its initial

Bold, transformational energy research projects win $151 million in funding
The Department of Energy today announced major funding for 37 ambitious research projects.

Increased stroke risk from birth control pills
Birth control pills nearly double the risk of stroke, according to a review article in MedLink Neurology.

Third sector still innovating despite hard times
Despite the recession, charities, social enterprises and voluntary organizations (the third sector) are still innovating, according to a publication out today from the Economic and Social Research Council.

Barrett's esophagus patients have same survival rates as general population
New Mayo Clinic research has found that survival rates of patients with Barrett's esophagus, which can be a precursor for esophageal cancer, are no different than the survival rates for the general population.

Do drug therapies raise risk of bladder cancer?
In her most recent study of possible triggers of cancer among northern New England residents, Dartmouth epidemiologist Margaret R.

Angina in the legs? Time to alert patients and physicians
Heart and Stroke Foundation researcher recommends that people over age 40 be screened for peripheral artery disease, which puts people at high risk for serious medical complications including heart disease, stroke and possible lower limb amputation.

LX211 highlighted as potential disease modifying therapy for noninfectious uveitis
LX211 (LUVENIQ; oral voclosporin) may become the first approved oral treatment capable of modifying the course of uveitis, otherwise inevitably associated with severe vision loss or substantial morbidity from steroid use.

New study reveals first ever method to genetically identify all 8 tuna species
A new paper published Oct. 27 in PLoS ONE, the online, open-access scientific journal, unveils for the first time a method to accurately distinguish between all eight tuna species from any kind of processed tissue using genetic sequencing.

Losing while cruising to the store
Contrary to what you might believe, living near a variety of restaurants, convenience stores, supermarkets and even fast food outlets actually lowers your risk for obesity, according to a new study from the University of Utah.

Faulty 'wiring' in the brain triggers onset of schizophrenia
A new study by researchers at the Institute of Psychiatry, King's College London, has discovered abnormalities in the white matter of the brain that seem to be critical for the timing of schizophrenia.

Changes in brain chemicals mark shifts in infant learning
When do you first leave the nest? Early in development infants of many species experience important transitions -- such as learning when to leave the mother's protection to start exploring the world.

A polymorphism of the μ-opioid receptor is linked to alcohol misuse among adolescents
A genetic study has examined the association between a polymorphism of the μ-opioid receptor (OPRM1) gene and alcohol misuse among adolescents.

Surveys for major neglected tropical diseases in sub-Saharan Africa can be integrated
It is possible to simultaneously survey a number of neglected tropical diseases in the challenging environment of Southern Sudan, according a new study.

Moderate amounts of protein per meal found best for building muscle
A recent study by UTMB metabolism researchers shows that only about the first 30 grams (just over one ounce) of dietary protein consumed in a meal actually produce muscle.

In combat zone, gastroenterologists put skills to test
Gastroenterologists working in Joint Base Balad, Iraq, present special cases that put their endoscopic skills to test while on deployment to diagnose and treat military dogs that provide vital protective roles in security and munitions detection.

The pain of torture can make the innocent seem guilty
Psychologists at Harvard University have found that the more a person appears to suffer when tortured, the guiltier they are perceived to be.

First national and evidence-based guidelines for brain cancer released
The first national treatment guidelines for brain metastases, which account for nearly 500,000 new cancers annually in the United States, were released today at the Congress of Neurological Surgeons in New Orleans.

Packages of care for alcohol use disorders in low- and middle-income countries
In the latest article in PLoS Medicine's series proposing the delivery of

For big athletes: Possible future risk
New primary research comparing the signs of metabolic syndrome in professional baseball and football players, reveals that the larger professional athletes -- football linemen in particular -- may encounter future health problems despite their rigorous exercise routines.

The Plant Cell launches 'Teaching Tools in Plant Biology'
The American Society of Plant Biologists announces the launch of

LA BioMed researcher to be honored
Rajnish Mehrotra, M.D., a LA BioMed investigator, will receive one of India's highest honors, the Hind Rattan Award.

Weekly and biweekly vitamin D2 prevents vitamin D deficiency
Boston University School of Medicine researchers have found that 50,000 International Units of vitamin D2, given weekly for eight weeks, effectively treats vitamin D deficiency.

New combination therapy looks promising against ulcer bacteria
Results of a new study reveal that a seven-day course of LOAD therapy is superior to LAC at eliminating the H. pylori bacterium in patients with gastritis and peptic ulcers.

Study finds delay in follow-up among African-American women receiving abnormal breast finding
A new analysis has identified a significant delay in follow-up times among African-American women after the finding of a suspicious breast abnormality.

Alternatively spliced tissue factor identified as promising new biomarker for aggressive cancers
A recently discovered form of the protein that triggers blood clotting may play a key role in the molecular mechanisms leading to the growth of certain metastatic cancers, according to new research reported by an international team of scientists.

A 2-for-1 for NASA's Aqua satellite: Lupit and 23W in Western Pacific
It seems like a common occurrence this season that there are two tropical cyclones spinning in the Western Pacific Ocean and this week, Lupit and newly formed 23W are proof.

Animals now picking up bugs from people, study shows
Globalization and industrialization are causing diseases to spread from humans to animals, a study has shown.

UCLA historian attempts to revive reputation of Union general, Reconstruction president
In a new book that combines biography of Ulysses S.

New center to open up new directions in cancer research
Northwestern University has been awarded a $13.6 million five-year grant from the National Cancer Institute to establish an interdisciplinary research center for the study of genes and their role in cancer.

UC Davis researchers identify dominant chemical that attracts mosquitoes to humans
Scientists at the University of California, Davis, have identified the dominant odor naturally produced in humans and birds that attracts the blood-feeding Culex mosquitoes, which transmits West Nile virus and other life-threatening diseases.

BIDMC transplant scientist Leo Otterbein, Ph.D., awarded NIH EUREKA grant
Leo Otterbein, Ph.D., a scientist in the Division of Transplantation at Beth Israel Deaconess Medical Center whose novel research has revealed medical applications for carbon monoxide gas, has been awarded a $1.4 million, four-year EUREKA grant from the National Institutes of Health.

Modified crops reveal hidden cost of resistance
Genetically modified squash plants that are resistant to a debilitating viral disease become more vulnerable to a fatal bacterial infection, according to biologists.

Mushrooms, water-repellants more similar than you might think
The same phenomenon that occurs when it's time for certain mushrooms to eject spores also occurs when dew droplets skitter across a surface that is highly water repellant.

Fitness levels decline with age, especially after 45
Men and women become gradually less fit with age, with declines accelerating after age 45, according to a report in the October 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Disappearing vowels 'caught' on tape in US midwest
Try to pronounce the words

Sperm may play leading role in spreading HIV
Sperm, and not just the fluid it bathes in, can transmit HIV to macrophages, T cells and dendritic cells (DCs), report a team led by Ana Ceballos at the University of Buenos Aires.

Fixing the flaw in emergency planning
Emergency response plans must include knowledge from the people who need to be protected if these plans are to help communities respond effectively to threats, write Drs.

Scientists use world's fastest supercomputer to model origins of the unseen universe
The model is one of the largest simulations of the distribution of matter in the universe, and aims to look at galaxy-scale mass concentrations above and beyond quantities seen in state-of-the-art sky surveys.

Rethinking the antibody-dependent enhancement dengue hemorrhagic fever model
Research published this week in PLoS Medicine challenges the dogma of the antibody-dependent enhancement model for the development of dengue hemorrhagic fever.
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