Brightsurf Science News & Current Events

April 01, 2011
'SKIP'-ing splicing forces tumor cells to undergo programmed cell death
When cells find themselves in a tight spot, the cell cycle regulator p21 halts the cell cycle, buying cells time to repair the damage, or if all else fails, to initiate programmed cell death.

From science fiction to research breakthrough
Focusing on interdisciplinary research is now leading to breakthroughs in bio nanotechnology research.

JCI online early table of contents: April 1, 2011
This press release contains summaries and links to articles that will appear in the April 1 online edition of the Journal of Clinical Investigation, including: Cat's out of the bag: PUMA contributes to ulcerative colitis, Gag order: how DNA silencing can promote cancer, New insight into the development of insulin resistance, and others.

First vaccine for viral hepatitis C could become a reality
Early data from phase I trials of an HCV vaccine presented today at the International Liver Congress show encouraging results, with high immunogenicity and good safety profile.

New studies provide beneficial insights expanding the pool of liver grafts and transplants
Findings from two new studies presented today at the International Liver Congress confirm that there are options for clinicians to expand the pool of liver grafts for use in patients with liver disease.

Green industry knowledge center introduced
A web-based knowledge center has premiered to help nursery and greenhouse growers and allied industries stay informed, improve production practices, protect the environment, and maintain profitability.

The Population Bomb: How we survived it
World population will reach 7 billion this year, prompting new concerns about whether the world will soon face a major population crisis.

Soy increases radiation's ability to kill lung cancer cells, study shows
A component in soybeans increases radiation's ability to kill lung cancer cells, according to a study published in the April issue of the Journal of Thoracic Oncology, the official monthly journal of the International Association for the Study of Lung Cancer.

A national survey: The value of otolaryngologists' services in America
In recent years reimbursement for surgical services has declined, failing to keep up with inflation and economic growth.

Research on satellite imagery aims to advance sustainable agriculture
Scientists evaluated the potential of multispectral reflectance and seven vegetation indices in the visible and near-infrared spectral range for discriminating and classifying bare soil and several horticultural irrigated crops.

In vivo RNAi screening identifies new regulators of liver regeneration
This study establishes a unique system to perform in vivo RNAi screens for genetically dissecting the cellular signaling networks that regulate hepatocyte proliferation during chronic liver damage.

Progress toward the clinical application of autologous induced pluripotent stem cells and gene repair therapy for treatment of familial hypercholesterolemia
Study shows, for the first time, the successful reprogramming of diseased human hepatocytes into induced pluripotent stem cells.

Breast health global initiative offers unprecedented tools for developing nations
A landmark breast health care publication reveals a multitude of barriers that keep women of developing nations from being screened and treated for breast cancer -- but offers tools to help countries improve their breast care programs.

Fratricide of HBV-specific CD8 T cells by NK cells mediated through the TRAIL pathway
A new study presented today at the International Liver Congress shows a novel pathway where activated natural killer cells expressing death ligands may excessively down-modulate the antiviral immune response in chronic HBV patients.

ORNL's Pennycook named Materials Research Society Fellow
Stephen Pennycook of the Department of Energy's Oak Ridge National Laboratory has been elected to the class of 2011 fellows of the Materials Research Society.

'Good cholesterol' nanoparticles seek and destroy cancer cells
High-density lipoprotein's hauls excess cholesterol to the liver for disposal, but new research suggests

Recovery Act-funded jobs program helps high school grads who have ASD
JobTIPS, a free, Web-based program unveiled today, aims to help youth with autism spectrum disorder (ASD) or other disabilities develop and maintain skills needed for successful employment.

TGen and PBS-Bio presents 2 abstracts at AACR conference
Predictive Biomarker Sciences (PBS-Bio) decodes the workings of drugs made by two private firms in abstracts presented this week at the 102nd annual conference of the American Association for Cancer Research.

When food is scarce, hungry female spiders alter mating preferences
Weather and environmental change can bring alterations -- and scarcity -- in food resources.

Many US women have children by more than one man
The first national study of the prevalence of multiple partner fertility shows that 28 percent of all US women with two or more children have children by more than one man.

Office of Naval Research Supports Exercise at Arctic Test Range
From collecting data on the environment to testing undersea communications, Ice Exercise 2011 (ICEX 2011), which runs March 15 through April 2, includes several Office of Naval Research (ONR) projects designed to improve naval operations in the Arctic.

Department of Psychiatry and Health Behavior well represented at international meeting
The Georgia Health Sciences University Department of Psychiatry and Health Behavior will have unprecedented representation at the International Congress on Schizophrenia Research for the second time.

New lung cancer staging system (TNM 7) better predicts local/regional recurrence, study shows
The new TNM 7 lung cancer staging system seems to be a better predictor of local or regional recurrence of lung cancer following surgery, according to a study published in the April issue of the Journal of Thoracic Oncology.

Oil prices affect inflation in Spain more than in the euro zone
Economists from the Bank of Spain's Research Department have published a study on the direct, indirect and 'second time around' effects of oil prices on the economies of Spain and those of the European Monetary Union (EMU).

The future looks bright for HCV patients who have failed to respond to current treatments
Highly anticipated data from a number of clinical trials presented for the first time at the International Liver Congress confirmed that a range of new proteases inhibitors will help treat patients who have previously failed therapy for the treatment of chronic hepatitis C.

Skywalker ensures optimal communication between neurons
Leuven - Patrik Verstreken (VIB/K.U.Leuven) has discovered the mechanism that ensures neurons can continue to send the right signals for long consecutive periods - a process that is disrupted in neurological diseases such as Parkinson's.

A new experimental diagnostic test able to quickly distinguish infection from tuberculosis disease
A potential new experimental diagnostic test able to quickly distinguish individuals with active tuberculosis (TB) from those with latent TB infection has been developed.

New geological field guide ranges from eastern Ohio through Pennsylvania to the Central Appalachian Valley and Ridge, USA
This new book from the Geological Society of America (GSA) features detailed descriptions of eight geological field trips offered during the March 2011 Joint Meeting of GSA's Northeastern and North-Central Sections in Pittsburgh, Pennsylvania.

Penn study suggests another avenue for detecting Alzheimer's disease
Researchers have determined that a well-known chemical process called acetylation has a previously unrecognized association with one of the biological processes associated with Alzheimer's disease and related disorders.

Short rotation energy crops could help meet UK's renewable energy targets
Planting short rotation energy crops on England's unused agricultural land could produce enough biomass to meet renewable energy targets without disrupting the food industry or the environment, according to research led by Professor Gail Taylor from the University of Southampton.

Gag order: how DNA silencing can promote cancer
Methylation of genes effectively silences them, and excess DNA methylation, particularly of cell cycle genes, promotes cancer formation.

When washing becomes a compulsion
Obsessive-compulsive disorder is often diagnosed too late in children and adolescents.

Sugar-grain sized meteorites rocked the climates of early Earth and Mars, according to new study
Bombardments of

Calculations with 14 quantum bits
Quantum physicists from the University of Innsbruck have set another world record: They have achieved controlled entanglement of 14 quantum bits (qubits) and, thus, realized the largest quantum register that has ever been produced.

Insulin could be Alzheimer's therapy
A low dose of insulin has been found to suppress the expression in the blood of four precursor proteins involved in the pathogenesis of Alzheimer's disease, according to new clinical research by University at Buffalo endocrinologists.

Got a craving for fast food? Skip the coffee, study says
A University of Guelph study has revealed not only that a healthy person's blood sugar levels spike after eating a high-fat meal, but that the spike doubles after having both a fatty meal and caffeinated coffee -- jumping to levels similar to those of people at risk for diabetes.

Children's health is focus of annual meeting of Pediatric Academic Societies
The latest scientific discoveries in children's health will be presented in Denver April 30-May 3, as part of the annual meeting of the Pediatric Academic Societies (PAS).

E. coli an unlikely contaminant of plant vascular systems
A technique developed by US Department of Agriculture (USDA) scientists for tracking pathogens has helped confirm that Escherichia coli is not likely to contaminate the internal vascular structure of field-grown leafy greens and thus increase the incidence of foodborne illness.

US CDC issues updated bloodstream infection prevention guidelines
New guidelines, released by the Centers for Disease Control and Prevention (CDC) and the Healthcare Infection Control Practices Advisory Committee (HICPAC) outline steps to eliminate bloodstream infections in patients with intravenous catheters, which are among the most deadly and costly healthcare-associated infections (HAIs).

EMMA milestone beams its way to a world first
A brand new technology that promises a range of applications from treating cancer to powering safer nuclear reactors has reached another world first in its development.

Manage biological invasions like natural disasters, biologists say
Biological invasions are often more economically damaging than natural disasters and warrant correspondingly large investments in preparedness and response planning, according to biologists writing in the April issue of BioScience.

April 2011 Geosphere highlights
The April 2011 Geosphere includes three articles designated for the latest Geosphere theme: Exploring the Deep Sea and Beyond.

New tool allows for an alternate method of prostate cancer diagnosis
Researchers have found that it may not be necessary to look for tumors directly in patients with prostate cancer -- analyzing non-tumor tissue may be an effective option, according to study results published in Cancer Research, a journal of the American Association for Cancer Research.

Internet program reduces infant and toddler sleep problems, helps moms sleep better too
A study in the April 1 issue of the journal SLEEP demonstrates that an Internet-based intervention was effective at reducing infant and toddler sleep disturbances, as well as providing positive, indirect benefits for maternal sleep, mood and confidence.

Writing assignments boost critical thinking skills for landscape design students
Higher-order thinking skills and the ability to integrate technical knowledge with practical applications are vital for employees, especially in today's challenging job market.

Why breast cancer is so poorly managed in developing countries
Breast cancer is on the rise in developing countries and mortality is high.

UGA studies explain spread of invasive ladybugs
A University of Georgia researcher studying invasive ladybugs has developed new models that help explain how these insects have spread so quickly and their potential impacts on native species.

Could maple syrup from Canada be the next champion food?
There's more good news about pure maple syrup from the University of Rhode Island (URI).

Surprising finding from smoke inhalation study
An award-winning Loyola University Health System study includes some unexpected findings about the immune systems of smoke-inhalation patients.

Advance in microchannel manufacturing opens new industry applications
Engineers at Oregon State University have invented a new way to use surface-mount adhesives in the production of low-temperature, microchannel heat exchangers--an advance that will make this promising technology much less expensive for many commercial applications--including next-generation computers, lasers, consumer electronics, automobile cooling systems, fuel processors, miniature heat pumps and more.

New opportunities for covalent drugs published by Avila scientists
Avila Therapeutics published a scientific article in Nature Reviews Drug Discovery titled

ORNL, industry collaboration puts spotlight on solar
Four manufacturers of solar energy components are working with the Department of Energy's Oak Ridge National Laboratory to address some of their biggest challenges.

Risk of death is high in older adults with sleep apnea and daytime sleepiness
A study in the April 1 issue of the journal Sleep suggests that the risk of death is more than two times higher in older adults who have sleep apnea and report struggling with excessive daytime sleepiness.

U-M experts: Parents trust doctors most when it comes to information about vaccine safety
Most parents get their information about vaccines from their children's doctors, but some also consider public health officials, other parents, friends and family members and even celebrities as sources of vaccine information.

Sleeping through danger: the dormouse approach to survival
Amid the general rejoicing over the first signs of spring, spare a thought for the humble dormouse, which is about to embark on the most dangerous period of its life.

Cat's out of the bag: PUMA contributes to ulcerative colitis
In this paper, Lin Zhang and colleagues found that in mice, a protein called PUMA (p53 upregulated modulator of apoptosis) was responsible for inducing apoptosis in the intestinal epithelium in response to inflammation; the absence of PUMA inhibited the inflammation-induced death of intestinal epithelial cells and development of colitis.

Jan-Åke Gustafsson leads team with $5.2M for prostate cancer research
University of Houston researchers will begin work to develop new methods for treating the most severe form of prostate cancer thanks to $5.2 million in grants awarded by the Cancer Prevention and Research Institute of Texas. is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to