Brightsurf Science News & Current Events

August 26, 2012
Diagnostic test shows potential to noninvasively identify significant coronary artery disease
Among patients with suspected or known coronary artery disease, use of a method that applies computational fluid dynamics to derive certain data from computed tomographic (CT) angiography demonstrated improved diagnostic accuracy vs.

UCSF, Mayo team discovers genomic variant that increases risk of some brain tumors
People who carry a

Global study suggests need for strategies to combat unhealthy lifestyles among the poor and the rich
The Prospective Urban Rural Epidemiology study involving 154,000 individuals from 628 communities reported on the patterns of diet, physical activity and smoking.

Novel blood test predicts sudden death risk patients who would benefit from ICDs
A novel blood test that predicts sudden death risk in heart failure patients is set to help physicians decide which patients would benefit from implantable cardioverter defibrillators.

Study could lead to improved outcomes for heart attack survivors
Research published in The Lancet could lead to improved long-term outcomes for heart attack survivors.

OAD shoots for the stars
The International Astronomical Union's (IAU) Office of Astronomy for Development program is announcing a number of new partnerships that will assist with the IAU's decadal strategic plan, aimed at realising the societal benefits of astronomy.

Researchers develop method to grow artificial tissues with embedded nanoscale sensors
A multi-institutional research team has developed a method for embedding networks of biocompatible nanoscale wires within engineered tissues.

Anti-clotting drugs yield similar results
The first trial to study patients with acute coronary syndrome who do not undergo coronary stenting or bypass surgery found no significant difference between two anti-clotting drugs - prasugrel and clopidogrel - in preventing the first occurrence of death, heart attack or stroke, according to Duke University Medical Center cardiologists.

New wave of technologies possible after ground-breaking analysis tool developed
A revolutionary tool created by scientists at the University of Sheffield has enabled researchers to analyze nanometer-sized devices without destroying them for the first time, opening the door to a new wave of technologies.

Sudden death less likely in exercise related cardiac arrests
People who have a cardiac arrest during or shortly after exercise are three times more likely to survive than those who have a cardiac arrest that is not exercise related, according to research presented at the ESC Congress 2012 today, August 26.

ECG is a cost effective method for diagnosing cardiac abnormalities in young athletes
Cardiovascular screening with ECG in young athletes is a cost effective way of diagnosing cardiac abnormalities, at just 138 Swiss Francs (about €115) per athlete.

Female gender increases stroke risk in AF patients aged over 75 years by 20%
Female gender increases the risk of stroke in patients with atrial fibrillation (AF) aged >75 years by 20%, according to a study presented today at the ESC Congress 2012.

Manipulating the microbiome could help manage weight
Vaccines and antibiotics may someday join caloric restriction or bariatric surgery as a way to regulate weight gain, according to a new study focused on the interactions between diet, the bacteria that live in the bowel, and the immune system.

Mayo, UCSF team discovers genomic variant that increases risk of brain tumors
People who carry a

The TRILOGY ACS study
The first trial to study the effect of platelet inhibition in patients with acute coronary syndromes managed medically without revascularisation has found no significant difference between prasugrel and clopidogrel in the prevention of death, myocardial infarction or stroke.

Drug eluting stents used less often in women than men
Drug eluting stents are used less often in women treated with percutaneous coronary intervention (PCI) for coronary artery disease than men treated with PCI for the same condition, according to research presented today, August 25, at the ESC Congress 2012.

The Aldo-DHF study
Mineralocorticoid receptor antagonists should be considered as a treatment option in hypertensive patients with diastolic heart failure, said Professor Burkert Pieske presenting results today of the Aldosterone Receptor Blockade in Diastolic Heart Failure (Aldo-DHF) study at ESC Congress 2012.

How ocean currents affect global climate is a question oceanographer may be close to answering
Florida State University oceanographer Kevin Speer has a

Controlling gene expression: How chromatin remodelers block a histone pass
Two opposing teams battle it out to regulate gene expression on the DNA playing field.

The PARAMOUNT study
The novel angiotensin receptor neprilysin inhibitor, LCZ696, demonstrated beneficial effects in heart failure patients with preserved ejection fraction (HFpEF), according to results of the PARAMOUNT (Prospective comparison of ARNI with ARB on Management of heart failure with preserved ejection fraction) trial.

Electrical storm is a potent risk factor for mortality and morbidity
Electrical storm is a potent risk factor for mortality and morbidity, according to research presented today at the ESC Congress 2012 by Dr.

Compound discovered that boosts effect of vaccines against HIV and flu
Oxford University scientists have discovered a compound that greatly boosts the effect of vaccines against viruses like flu, HIV and herpes in mice.

Passive smoking increases platelet activation in healthy people
Passive smoking increases platelet activation in healthy people, according to research presented at the ESC Congress 2012 today, August 25, by Dr.

Obesity triggers AF in fertile women
Obesity triggers atrial fibrillation in fertile women, according to research presented today at the ESC Congress 2012 by Dr.

The DeFACTO study
Data presented today from the prospective Determination of Fractional Flow Reserve by Anatomic Computed Tomographic Angiography (DeFACTO) study show that, when compared to standard coronary angiography, the non-invasive assessment of fractional flow reserve by computed tomography provides a more accurate determination of which lesions require invasive evaluation.

Weighing molecules 1 at a time
A team led by scientists at the California Institute of Technology has made the first-ever mechanical device that can measure the mass of individual molecules one at a time.

New drug shows promising results for heart failure patients
A phase two trial of a first-in-class compound called LCZ696 has shown promising results which may lead to improved treatment for around half of all heart failure cases, according to research published in the Lancet.

Scientists identify new gene that influences survival in ALS
A team of scientists, including faculty at the University of Massachusetts Medical School, have discovered a gene that influences survival time in amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

A lesson in sleep learning
Associations formed in the brains of sleeping volunteers remained intact when the subjects were awake.

New device to remove stroke-causing blood clots proves better than standard tool
Stroke is the fourth leading cause of death and a common cause of long-term disability in the United States, but doctors have very few proven treatment methods.

The PURE study
Healthy foods such as fruits and vegetables, proteins and non-saturated fats are consumed more often by the wealthy while poorer people consume more carbohydrates, concludes a new study involving people from 17 countries.

Vitamin B12 deficiency: Tracking the genetic causes
Vitamin B12 is essential to human health. However, some people have inherited conditions that leave them unable to process vitamin B12.

Copeptin predicts prognosis in HF patients
Copeptin predicts prognosis in patients with heart failure, according to research presented at the ESC Congress today, August 25, by Professor Stefan Stork from Germany.

Continuous spinal cord stimulation improves heart function
Spinal cord stimulation improves heart function and could become a novel treatment option for heart failure, according to research presented at the ESC Congress 2012 today by Professor Hung-Fat Tse from Hong Kong.

Study: Clot removal devices successful tools for acute ischemic stroke treatment
Every 40 seconds, someone in the United States has a stroke, usually caused when a clot blocks an artery that supplies blood to the brain.

Compounds activate key cancer enzyme to interfere with tumor formation
Scientists have known for decades that cancer cells use more glucose than healthy cells, feeding the growth of some types of tumors.

Merging the biological and the electronic
Harvard scientists have, for the first, time created a type of

Next generation of mechanical flow restoration devices could offer improvements in treatment of stroke patients
Two innovative new devices could offer significant improvements in the treatment of stroke patients who aren't eligible for or fail to respond to drug treatment, according to two new controlled clinical trials published in the Lancet.

Novel anti-platelet therapy reduces risk of cardiac events in patients with history of heart attack
Adding vorapaxar, an investigational platelet blocker, to standard antiplatelet therapy significantly reduces the long-term risk of recurrent cardiovascular events beyond one year in patients with a history of a prior heart attack.

Pitt: Targeted oxidation-blocker prevents secondary damage after traumatic brain injury
Treatment with an agent that blocks the oxidation of an important component of the mitochondrial membrane prevented the secondary damage of severe traumatic brain injury and preserved function that would otherwise have been impaired, according to research team from the University of Pittsburgh School of Medicine, Graduate School of Public Health and Department of Chemistry in a report published online today in Nature Neuroscience.

Median follow-up results from the ALTITUDE study, stopped prematurely in December 2011
Preliminary results from the Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE) do not support administration of aliskiren on top of standard therapy with renin-angiotensin-aldosterone system blockade in type 2 diabetics at high risk of cardiovascular and renal events, according to Professor Hans-Henrik Parving from Rigshospitalet, University of Copenhagen, Denmark.

Women with acute heart failure have similar in-hospital mortality to men but are less treated
Women with acute heart failure have similar in-hospital mortality to men but are less treated in the real world, according to results from the global ALARM-HF registry presented today, Sunday, August 26, at the ESC Congress 2012.
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