Brightsurf Science News & Current Events

March 10, 2013
Early detection of MS treatment complication may improve survival
The drug natalizumab is effective for treating multiple sclerosis, but it increases the risk of a rare but potentially fatal brain infection called progressive multifocal leukoencephalopathy (PML).

Validated pre-procedure risk score reduces bleeding complications and can shorten stays
A clinical decision support tool helped physicians identify patients at high risk of bleeding complications prior to undergoing a coronary intervention procedure and helped guide the use of bleeding avoidance strategies, leading to less complications and a shorter hospital stay, according to a study being presented March 10 at the American College of Cardiology Scientific Sessions.

New biolimus stent equal to everolimus stent at 1 year
In a match-up of Japan's top drug-releasing stent and a new device featuring a biodegradable coating, the newcomer delivered statistically comparable one-year results, according to data from the NEXT trial presented today at the American College of Cardiology's 62nd Annual Scientific Session.

Amplified greenhouse effect shaping North into South
An international team has published a study in the journal Natural Climate Change showing that, as the cover of snow and ice in the northern latitudes has diminished in recent years, the temperature over the northern land mass has increased at different rates during the four seasons, causing a reduction in temperature and vegetation seasonality in this area.

A new drug reduces heart damage
A single dose of an investigational anti-inflammatory drug called inclacumab considerably reduces damage to heart muscle during angioplasty (the opening of a blocked artery.)

Mummy CT scans show preindustrial hunter gatherers had clogged arteries
Like nearly 4.6 million Americans, ancient hunter-gatherers also suffered from clogged arteries, revealing that the plaque build-up causing blood clots, heart attacks and strokes is not just a result of fatty diets or couch potato habits.

Significant reduction in temperature and vegetation seasonality over northern latitudes
An international team of authors from 17 institutions in seven countries, published a study in the journal Nature Climate Change on March 10, 2013.

Entomology meeting in Lancaster
Thousands of insects and a swarm of entomologists will converge on Lancaster for the 84th Annual Meeting of the Entomological Society of America's Eastern Branch, which will include a free public program for kids and parents called

Sudden death in young athletes: Important causes not identified by the screening process
Even though young athletes are required to receive health screens to be cleared to play sports, those tests failed to detect important cardiovascular abnormalities in cleared players, and many were allowed to play despite suspicions of dangerous cardiovascular conditions, according to a large registry study of patients who died from sudden death, being presented March 10 by Kevin Harris, M.D., research cardiologist at the Minneapolis Heart Institute Foundation.

Mummies study reveals that hardening of the arteries may have been a global problem in the ancient world
A study of 137 mummies from four different geographical regions, spanning 4000 years of human history, has revealed that atherosclerosis, or hardening and narrowing of the arteries -- the disease that causes heart attacks and strokes -- may have been much more common among ancient peoples than previously thought.

Fewer adverse events with 'double kissing' crush stent than culotte
Patients with a type of coronary lesion linked with poor prognosis fared significantly better with the stent technique known as double kissing crush than with culotte stenting, according to data from the DKCRUSH-III trial presented today at the American College of Cardiology's 62nd Annual Scientific Session.

Drug protects against kidney injury from imaging dye in ACS patients
High doses of a popular cholesterol-lowering drug significantly reduced the rate of acute kidney injury caused by dye used in imaging in acute coronary syndrome patients who underwent a coronary procedure, according to research presented today at the American College of Cardiology's 62nd Annual Scientific Session.

Encouraging early results for redesigned Sapien valve
The new Sapien XT aortic valve showed a non-significantly lower rate of death and strokes at 30 days than the original model, and both valves demonstrated notably better short-term outcomes than seen with the Sapien system in PARTNER I, according to the first results from the PARTNER II study presented today at the American College of Cardiology's 62nd Annual Scientific Session.

Selectively manipulating protein modifications
Protein activity is strictly regulated. Incorrect or poor protein regulation can lead to uncontrolled growth and thus cancer or chronic inflammation.

Are tropical forests resilient to global warming?
Tropical forests are less likely to lose biomass -- plants and plant material -- in response to greenhouse gas emissions over the twenty-first century than may previously have been thought, suggests a study published online this week in Nature Geoscience.

New anti-clotting drug more effective than current treatment
A new and experimental anti-clotting drug, cangrelor, proved better than the commonly used clopidogrel and was significantly more effective at preventing blood clots in a large trial of patients who underwent coronary stent procedures.

Results released for first multicenter study of hybrid revascularization
The first multicenter study of hybrid revascularization shows that the emerging procedure for treating coronary artery disease has a similar rate of major adverse events in the first year, compared with percutaneous intervention (stenting).

Store donated blood for more than 3 weeks? Say NO (nitric oxide)
Transfusion of donated blood more than three weeks old results in impaired blood vessel function, a new study of hospital patients shows.

Can hormone help treat multiple sclerosis long-term?
A new study suggests that treatment with adrenocorticotropic hormone may be helpful for people whose multiple sclerosis is not well-controlled through their regular treatment.

Study: Diabetic medication may protect patients from developing heart failure
A class of medications commonly prescribed to lower blood sugar in diabetic patients appears to protect them from developing heart failure, according to a study at Henry Ford Hospital in Detroit.

Cleveland Clinic research shows anemia drug does not improve health of anemic heart failure patients
Researchers from Cleveland Clinic and Sweden-based Sahlgrenska University Hospital have found that a commonly used drug to treat anemia in heart failure patients -- darbepoetin alfa -- does not improve patients' health, nor does it reduce their risk of death from heart failure.

Cangrelor superior to clopidogrel in CHAMPION PHOENIX trial
The experimental anti-clotting drug cangrelor solidly outperformed commonly used clopidogrel in a large global trial of patients who underwent coronary stent procedures, according to data from the phase III CHAMPION PHOENIX study presented today at the American College of Cardiology's 62nd Annual Scientific Session.

ECG screening for competitive athletes would not prevent sudden death
The risk of cardiovascular sudden death was very small and only about 30 percent of the incidence were due to diseases that could be reliably detected by pre-participation screening, even with 12-lead ECGs, according to research in a US high school athlete population presented March 10 at the American College of Cardiology Scientific Sessions.
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