Brightsurf Science News & Current Events

June 02, 2013
RET rearrangement a new oncogene and potential target in lung cancer
In results presented at ASCO 2013, a University of Colorado Cancer Center study provides important details for a recently identified driver and target in lung adenocarcinoma: Rearrangement of the gene RET.

Study links workplace daylight exposure to sleep, activity and quality of life
A new study demonstrates a strong relationship between workplace daylight exposure and office workers' sleep, activity and quality of life.

Therapy that heats and destroys bone tumors eases patients' pain
Patients with cancer that has spread to their bones are often treated with radiation therapy to reduce pain.

New cancer drug shows promise for treating advanced melanoma
Results from the first clinical trial of lambrolizumab in patients with advanced melanoma shows significant anti-tumor activity with very manageable side effects in patients with advanced melanoma, the deadliest form of skin cancer.

Study suggests that night work may impair glucose tolerance
A new study suggests that night work may impair glucose tolerance, supporting a causal role of night work in the increased risk of type 2 diabetes among shift workers.

Test helps target glioblastoma patients most likely to benefit from bevacizumab
A new test may help identify newly diagnosed glioblastoma patients more likely to benefit from bevacizumab (Avastin), according to new research from the University of Texas MD Anderson Cancer Center.

Researchers document acceleration of ocean denitrification during deglaciation
As ice sheets melted during the deglaciation of the last ice age and global oceans warmed, oceanic oxygen levels decreased and

Update on determination of death: Experts call for international consensus
The criteria used to diagnose both circulatory and brain death in a patient are subject to variability and as such can be controversial.

Bevacizumab offers no benefit for newly diagnosed glioblastoma, M.D. Anderson-led study finds
Bevacizumab (Avastin) failed to increase overall survival or statistically significant progression-free survival for glioblastoma patients in the frontline setting.

Combination of drugs produces dramatic tumor responses in advanced melanoma patients
The combination of the immunotherapy drug ipilimumab and the investigational antibody drug nivolumab led to long-lasting tumor shrinkage in more than half of patients with metastatic melanoma, according to new research from Memorial Sloan-Kettering Cancer Center.

Printing innovations provide 10-fold improvement in organic electronics
SLAC and Stanford researchers have developed a new, printing process for organic thin-film electronics that results in films of strikingly higher quality.

US oncologists report high career satisfaction, yet many suffer symptoms of burnout
Even though a majority of US oncologists report satisfaction with their careers, many say they have experienced at least one symptom of burnout, a Mayo Clinic-led study has found.

A step closer to artificial livers
Researchers identify compounds that help liver cells grow outside the body.

Some patients with treatment-resistant colorectal cancers may have a new option
A subset of colorectal cancers responds to anti-epidermal growth factor receptor (anti-EGFR) therapies, but develops resistance within months.

New method of mass-producing high-quality DNA molecules
A new method of manufacturing short, single-stranded DNA molecules can solve many of the problems associated with current production methods.

Europe needs to engage and invest in national R&D budgets
In June's edition of Physics World Portugal's former science and technology minister, José Mariano Gago, calls for more investment in, and engagement with, national science budgets in light of the European Union's stagnated investment.

Growth factor responsible for triggering hair follicle generation during wound healing identified
Penn researchers have determined the role of a key growth factor, found in skin cells of limited quantities in humans, which helps hair follicles form and regenerate during the wound healing process.

Genome hints at markers for higher-producing, better-tasting chocolate
The freshly sequenced genome of the most commonly cultivated cacao plant in the world is revealed in the open access journal Genome Biology this week.

Abnormalities in HER2 gene found in wide variety of advanced cancers
The HER2 growth-factor gene is known to be over-active in breast and gastro-esophageal cancers.

Addition of bevacizumab to initial treatment for brain tumors does not extend patients' lives
Results of a randomized Phase III clinical trial conducted by the Radiation Therapy Oncology Group determined that adding bevacizumab to initial treatment for glioblastoma did not improve patient overall survival or progression-free survival,.

Narcolepsy study finds surprising increase in neurons that produce histamine
A new study provides surprising evidence that people with narcolepsy have an increased number of neurons that produce histamine, suggesting that histamine signaling may be a novel therapeutic target for this potentially disabling sleep disorder.

Targeted therapy sorafenib shows success in advanced differentiated thyroid cancer patients
The kidney and liver cancer drug sorafenib holds metastatic thyroid cancer at bay for nearly twice as long as a placebo, according to results of a randomized phase III trial, which will be presented today by a researcher from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania in a plenary session during the American Society of Clinical Oncology's annual meeting.
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